Research and Reviews : A Journal of Biotechnology
Volume 5, Issue 3 (2015)
Published
Table of contents
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A Comparative Study on the Expression of Various Housekeeping Genes in the Organs of Different Mice Strains
Abstract: The expression of housekeeping genes significantly varies between organs and between strains. Therefore, it is highly required to find out the housekeeping gene that can be the most useful and reliable one, where inter-organ comparative studies on gene expression need to be performed. Keeping this issue in consideration, a comparative study of different housekeeping genes using organs of four different strains of mice was performed. Different organs, i.e., liver, kidney, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 3, 2015 · pp. 1–10 Read article
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Estimation of Genetic Diversity in Some Species of Meliaceae Family through RAPD Technique
Abstract: Random amplified polymorphic DNA (RAPD) analysis has proved to be useful in determining genetic relationship and variation in many plant species, result of RAPD analysis can be used to determine genetic distances and relatedness within or among species, which can then be utilized in construction of phytogenetic. RAPD analysis could also provide useful insights into the phylogenetic relationship. RAPD is a polymerase chain reaction (PCR), which is based on dominant …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 3, 2015 · pp. 11–17 Read article
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3D-QSAR and Molecular Docking Studies of Triazol-Cycloalkanol Derivatives Used as Potent 3-Dehydroquinase II Inhibitors Against Mycobacterium tuberculosis
Abstract: Tuberculosis is a life threatening infectious disease caused by gram positive bacteria mycobacterium tuberculosis. Emergence of drug resistance, multi drug resistance and extensively drug resistance strain of mycobacterium make the situation more worst. It increases the mortality rate of tuberculosis patient, time duration and cost of treatment. Various inhibitors and drug molecules are designed to combat this fatal disease. Enzymes of shikimate pathway are responsible for production of essential amino …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 3, 2015 · pp. 18–28 Read article
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3D-QSAR Studies, Molecular Docking and ADME Property Prediction of 3, 4-dihydroxy Pyrrolidine Derivatives Used as A Potent Glycosidase Inhibitors Against Shiga Toxin
Abstract: Diarrhea is usually brought on by gastrointestinal infection caused by bacteria. The symptoms may range from mild abdominal discomfort to full blown dysentery, characterized by cramps, diarrhea, fever, vomiting, blood, pus, or mucus in stools. The Shiga toxin—a single 30 KDa A-subunit and 7 KDa B-subunit, binding to GB3 on target eukaryotic cells, the stx-receptor complex is internalized and locates with endosomes. In this study, four potent novel glycosidase inhibitors …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 3, 2015 · pp. 29–34 Read article
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Natural Products: A Prospective Tactic to Unite Nature and Disease
Abstract: The most primitive and effective method from pre-historic time to heal injuries, cure disease and relieve suffering; is treatment with the help of plants extract. Resistance to anti microbial agents has lead to treatment failure and the shift of medical care from orthodox to herbal medicine. Most of the herbal medicines in use await validation of their claimed effects and possibly the development of novel antimicrobial drugs from them. Every …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 3, 2015 · pp. 35–38 Read article
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Pharmacognostical and Physicochemical Studies of Elytraria acaulis (L.F.) Lindau
Abstract: Nature has bestowed on us a very rich botanical wealth and a large number of diverse types of plants grow in different parts of the country. Herbal medicine is still the main stay of about 75–80% of the whole population, and the major part of traditional therapy involves the use of plant extract and their active constituents. In recent years there has been rapid increase in the standardization of selected …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 3, 2015 · pp. 39–43 Read article