direct compression

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• Published Subscription Original Research 11 Oct 2025

  Development and Optimization of Orally Disintegrating Tablets (ODTs) Containing Standardized Curcumin Extract for Enhanced Bioavailability and Patient Compliance

  By Rupesh Kumar Pandey, Kamalesh Mistry, Dhananjay Mistry, Shivam Rongpi, Pratyush Kumar Brahma, Mitul Bhoi

  Abstract: This research centers on creating and perfecting orally disintegrating tablets with standardized curcumin extract to both increase its bioavailability and promote better patient adherence. Although curcumin has numerous therapeutic applications. It remains clinically ineffective due to its poor aqueous solubility and bioavailability constraints. The development of orally disintegrating tablets involved direct compression with various levels of superdisintegrants including sodium starch glycolate and cross povidone to address existing challenges. Research teams …

  Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 1–06 Read article →