Biodegradable polymer matrix

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• Published Subscription Original Research Special issue 20 Mar 2026

  Development of Biodegradable Poly (Lactic-Co-Glycolic Acid) (PLGA) Nanoparticles for Sustained Release of Insulin

  By Amit Kumar Singh, Anuradha Singh, Raosaheb Y. Ghegade, Shubham Sharma, Chetna Devkar, Kavitha C, Manisha S Nangude, Anagha Amit Sarvadnya, Mrinal Kanti Bhoumik

  Abstract: This research outlines the creation of biodegradable composite nanoparticles made from poly (lactic-co-glycolic acid) (PLGA) designed for the sustained release of insulin. The emphasis is on the interactions between the polymer and the drug at the interface, along with the dynamics of the release matrix. The in vitro release kinetics, surface morphology, encapsulation efficiency, particle size, and polydispersity of insulin-loaded PLGA nanoparticles were analyzed following their production via a double …

  Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1690–1699 Read article →