antibiotics
13 articles · search the full text for this term
-
The Global and Regional Challenge of Pan-Antibiotic Resistance: A Review of Emerging Threats and Mechanisms
Abstract: Antimicrobial resistance (AMR) is one of the major and most intricate threats to the health of the 21st century as it is core to the undermined expertise of the common clinical practice and public health security worldwide. The problem is characterized by the extensive development of bacterial pathogens into extremely drug-resistant (XDR) and pan-drug-resistant (PDR) so- called superbugs faster than it can be done with therapeutics. It is a synthesis …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
-
Antimicrobial Resistance: - A Growing Serious Threat for Global Public Health
Abstract: Antibiotics, among the most significant discoveries of the 20th century, have prevented infectious diseases from claiming millions of lives. However, their widespread use and misuse have created strong selection pressure, enabling microbes to develop antimicrobial resistance (AMR) to many drugs. Over time, AMR has spread primarily through human-to-human contact, both within healthcare settings and in the community. It is driven by a complex interplay of healthcare and agricultural factors, including …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
-
Synthesis, Antibacterial Evaluation and Antifungal Study of New Biochemical Derivatives
Abstract: Bacterial and fungal infections have become widespread recently due to the spread of epidemics, diseases, and bacterial infections. As a result, infection rates have increased, prompting many researchers to develop new antibiotics to reduce the spread of these prevalent diseases. Researchers have prepared biochemical compounds similar in structure to drugs that eliminate infections and reduce their spread. One such derivative is imidazole; a well-known compound used in many medications for …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 19–28 Read article
-
A study of The impact of Antibiotic Pollution and The types of Environmental Pollution It causes
Abstract: Antibiotics are essential biological drugs for human health and are the cornerstone of treating infections caused by various bacteria and viruses. However, they also pose a significant risk if misused, as each antibiotic is designed for a specific type of bacteria. Sometimes, due to the evolution of bacteria, many antibiotics have become ineffective and resistant to contamination and infection. Therefore, they can have the opposite effect, polluting the environment instead …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 41–46 Read article
-
A study on Antibiotic Resistance: An Analysis of Molecular Mechanisms and Therapeutic Implications
Abstract: Antibiotic resistance (AR) represents one of the most critical existential threats to global public health, rapidly eroding the efficacy of established antimicrobial therapies and portending a return to the pre-antibiotic era. This analysis explores the intricate molecular landscape defining this crisis, focusing specifically on the primary mechanisms of action (MoA) utilized by major antibiotic classes—including cell wall inhibitors, protein synthesis inhibitors, and nucleic acid synthesis inhibitors—and the corresponding, diverse mechanisms …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 9–21 Read article
-
Evaluating the Effects of Self-Care Practices on Dermatology Patients at Sharda University Hospital
Abstract: Self-care is the ability of individuals, families and communities to promote their own health, prevent disease, maintain health, and to cope with illness with or without the support of a health or care worker." (WHO, 2020) This study looked into the demographics and self-care activities of patients who visited the Dermatology Department at Sharda Hospital. A descriptive survey design was used, with 50 participants aged 18-45 years selected using convenience …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 2, 2025 Read article
-
Extended-spectrum beta-lactamases (ESBLs) and Metallo-beta-lactamases (MBLs): A Review
Abstract: Gram-negative bacteria produce extended-spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs), enzymes that play a crucial role in antibiotic resistance. These enzymes enable the bacteria to withstand a wide array of beta-lactam antibiotics, including penicillins, cephalosporins, and carbapenems. The production of these enzymes, particularly by organisms, such as Escherichia coli and Klebsiella pneumoniae, complicates treatment options for severe infections, leading to increased morbidity and mortality in clinical settings. ESBLs are primarily responsible …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 8–19 Read article
-
Antibiotic Resistance in Microbes: History, Mechanisms, Therapeutic Approaches, and Strategies for Mitigation
Abstract: The global emergence of clinically significant antibiotic resistance is increasingly linked to the environment. Antimicrobials, metals, and biocides are just a few of the substances that are released into the environment through paths that are regulated by environmental regulators. Consequently, environmental regulators ought to be heavily involved in developing national and international antimicrobial resistance (AMR) measures. Antimicrobial compounds from pharmaceutical waste, agricultural runoff, and wastewater discharge contribute to the spread …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–11 Read article
-
Bacteriophage Therapy in Dairy Farming: A Potential Alternative to Antibiotics
Abstract: The widespread use of antibiotics in dairy farming to control bacterial infections has led to significant challenges, including the emergence of antibiotic-resistant bacteria and concerns over antibiotic residues in milk. Consequently, there is an increasing demand for alternative approaches to control bacterial infections in dairy cattle. One promising solution is bacteriophage therapy, which uses viruses that selectively infect and destroy bacteria. As a result, the need for new strategies to …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 2, 2024 · pp. 1–5 Read article
-
Antibiotic Resistance Profiles of Salmonella Isolated from Al-Gharraf River and Iraqi Sewage
Abstract: Salmonella is a Gram-negative bacterium belonging to the Enterobacteriaceae family. It has a rod-shaped (bacillus) structure. Salmonella is a prominent contributor to gastrointestinal sickness worldwide. In addition, it is the causative agent of more systemic severe disorders such as typhoid and paratyphoid fevers. Salmonella is primarily recognized as pathogens transmitted by water and food to people and animals. Salmonella is often found in water-related epidemics, even though it is routinely …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
-
Meta-Analysis on Antibiotic Resistance and Its Irrational Use in India: Need of Antibiotic Stewardship Program Implementation
Abstract: Antibiotic resistance is a major health issue in developing countries. This issue is increasing exponentially due to increased consumption, easy availability of medicine and higher incidence of inappropriate use. Moreover, India stands as one among the highest infectious disease burdened country in the world. This study aims to conduct a statistical analysis to find the association between antibiotic resistance and its irrational use in India. Thereby, emphasizing the need for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 6–14 Read article
-
Patient Profile and Antimicrobial Susceptibility Testing of Clinically Isolates In E. coli
Abstract: Escherichia coli, commonly known as E. coli, is a prevalent bacterium capable of causing infections in humans. The development of antimicrobial resistance in E. coli poses a significant public health issue. This study aimed to determine the patient profile and antimicrobial susceptibility patterns of clinically isolated E. coli. A retrospective study was carried out on E. coli samples collected from clinical specimens within a hospital environment. Patient profiles, including age, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 1, 2024 · pp. 32–47 Read article
-
Antibiotic Resistance: Molecular Mechanisms of Resistance
Abstract: Antibiotics are called as ‘Wonder Drugs’, the miracles of modern sciences. They help combat bacteria and prevent their growth. But due to unmonitored and uncontrolled consumption of these antibiotics, there is an emergence of antibiotic resistance. This has led to a series of downfall in the therapeutic potency and efficacy of many drugs. More and more bacteria are becoming Multi-Drug Resistant (MDR); such highly resistant strains of certain bacteria are …
Published in Research and Reviews: A Journal of Microbiology and Virology Read article