Antibiotic Resistance: Molecular Mechanisms of Resistance

Sandip Zine; Parth Mehta; Ankita Rai; Sayli Sawant

Abstract

Antibiotics are called as ‘Wonder Drugs’, the miracles of modern sciences. They help combat bacteria and prevent their growth. But due to unmonitored and uncontrolled consumption of these antibiotics, there is an emergence of antibiotic resistance. This has led to a series of downfall in the therapeutic potency and efficacy of many drugs. More and more bacteria are becoming Multi-Drug Resistant (MDR); such highly resistant strains of certain bacteria are called Superbugs. The misuse and overconsumption of many antibiotics, has led to a steep rise in the number of antibiotic-resistant strains at a global level, thus elevating global mortality and morbidity rates. This prompted World health Organisation in 2011 to coin a slogan “No action today, no cure tomorrow”. This review gives a piece of detailed information on the origin, molecular mechanisms of antibiotic resistance, supported by factual data and case studies.

Abstract

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