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321 articles for “system biology”
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Pathophysiology Reimagined: Integrating Systems Biology and AI for Disease Understanding
Abstract: Pathophysiology, the study of disease mechanisms at molecular, cellular, and systemic levels, has traditionally relied on reductionist approaches that often fail to capture the complex, dynamic, and interconnected nature of biological systems. Diseases such as cancer, neurodegenerative disorders, and infectious diseases arise from intricate interactions among genetic, epigenetic, metabolic, and environmental factors, necessitating integrative, data-driven methodologies for a deeper understanding. Systems biology has emerged as a powerful approach by leveraging …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 63–71 Read article
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Advances in Biological Systems Modeling for Predicting Drug Effects in Chronic Disease
Abstract: Biological systems modeling has emerged as a promising tool for understanding and predicting the effects of drugs in the treatment of chronic diseases. Chronic diseases, such as diabetes, cardiovascular diseases, and neurodegenerative disorders pose significant challenges to traditional drug development due to their complex, multifactorial nature. Systems biology approaches, which integrate computational modeling with experimental data, provide a holistic view of disease mechanisms and treatment responses. This review explores recent …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 17–22 Read article
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Introduction to Biological Networks and their Contributions to Systems Biology
Abstract: Biological networks provide a conceptual framework to represent and analyze the intricate interconnections among the numerous components that make up living systems. This review paper elucidates the foundational principles of networks and their diverse applications in systems biology, highlighting their crucial role in understanding the inherent complexity of biological processes. Utilizing graph theory, these networks represent entities like genes, proteins, and metabolites as nodes, with their interactions depicted as edges. …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 53–70 Read article
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Advancing Asthma Management: The Synergy of Systems Biology, Artificial Intelligence, and Next-Generation Therapeutics
Abstract: Asthma is an inflammatory disorder of the respiratory tract that is chronic and heterogeneous in nature and has various effects on millions of people. Being a chronic inflammatory disease, asthma remains incurable and the major conventional treatments offer limited success due to the mask nature of its pathophysiology. Systems biology/(AI), and next-generation has greatly enhanced knowledge and the management of asthma. The approaches based on gene, transcript, protein, and metabolite …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 1–12 Read article
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The Rise of Fractional Calculus: Novel Applications in Engineering and Biological Systems
Abstract: Fractional calculus (FC) is an advanced mathematical framework that generalizes the classical concepts of differentiation and integration to non-integer, or fractional, orders. This extension of traditional calculus allows for the modeling of complex dynamic systems that exhibit behavior not easily captured by integer-order differential equations. Over the last few decades, fractional calculus has seen a rapid rise in popularity, particularly in applied mathematics, engineering, and biological sciences, due to its …
Published in Recent Trends in Mathematics · Vol. 1, Issue 2, 2024 · pp. 7–11 Read article
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Electromagnetic Field Effects on Biological Systems and Safety Evaluation of Microwave Exposure
Abstract: The increasing use of wireless communication systems, radar technologies, and microwave- based devices has raised growing concerns regarding the potential biological effects of electromagnetic fields (EMFs) on living systems. This review paper investigates the interaction between electromagnetic field exposure, particularly in the microwave frequency range, and biological tissues, with a focus on safety implications and risk assessment. Microwave radiation, commonly emitted from mobile phones, Wi-Fi routers, and industrial equipment, can …
Published in Journal of Microwave Engineering and Technologies · Vol. 13, Issue 1, 2026 · pp. 26–33 Read article
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An Overview of Bioinformatics
Abstract: What is bioinformatics? Biology and computer science? How are they related to each other? This question, I believe, could have been raised even in the nineteenth century, when computer and biological technologies were just emerging. The great Louis Pasteur (1822–1895) was researching the relationship between the presence of a particular microorganism and alcohol fermentation in a particular French city. Ada Lovelace, a mathematician who shared Charles Babbage’s vision, was attempting …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 2, 2022 · pp. 8–11 Read article
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From Photoreceptors to Photoelectrodes: Integrating Biological Light-Harvesting Mechanisms with Nanostructured Photoelectrochemical Systems
Abstract: The efficient conversion of solar energy into electrical and chemical energy is a major scientific challenge of the twenty-first century. Natural photoreceptors provide valuable models for addressing this challenge because they have evolved highly efficient mechanisms for capturing and converting light energy. Biological systems such as rhodopsins, bacteriorhodopsins, proteorhodopsins, cryptochromes, phototropins, and phytochromes employ chromophore-driven photoinduced electron and proton transfer processes to initiate a wide range of physiological responses, including …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 2, 2026 · pp. 25–33 Read article
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Biohybrid Machines: Integrating Organic Systems with Robotics for Enhanced Mobility and Function
Abstract: Biohybrid machines are an innovative frontier at the intersection of biological systems and robotics. This research field explores the integration of living organisms with machines, combining the advantageous characteristics of both synthetic materials and biological components. Through the integration of organic cells, tissues, and even entire organisms with robotics, biohybrid machines possess unique capabilities such as self-healing, adaptability, and energy efficiency, making them more suitable for tasks that require flexibility …
Published in Trends in Machine design · Vol. 12, Issue 1, 2025 · pp. 30–37 Read article
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Digital Frontiers in Life Sciences: The Transformative Role of Computing in Modern Biology
Abstract: The integration of computers in the biological sciences has revolutionized research and experimentation, facilitating advancements in areas such as genomics, bioinformatics, systems biology, and ecological modeling. The ability to process vast amounts of biological data efficiently has transformed how scientists study complex biological systems and phenomena. Computational tools enable the analysis of DNA sequences, protein structures, metabolic pathways, and ecological dynamics, which were previously beyond the reach of traditional laboratory …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 1, 2026 Read article
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Photoreceptor Dynamics: Light Sensing and Cellular Responses for Photochemistry
Abstract: Photoreceptor dynamics represent a fundamental aspect of photochemistry, encompassing the mechanisms by which biological systems detect and respond to light stimuli. Photoreceptors are specialized proteins that undergo structural and functional changes upon photon absorption, initiating a cascade of molecular events that translate light signals into cellular responses. These proteins are ubiquitous across life forms, including microbial rhodopsins, plant phytochromes, and animal opsins, each finely tuned to specific wavelengths and light …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 2, 2025 · pp. 28–32 Read article
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Harnessing Bacteria for Next-Generation Data Storage Technologies – A Review
Abstract: The exponential increase in global digital information has created a pressing need for storage technologies that are more durable, compact, and sustainable than conventional electronic media. While hard drives, solid-state drives, and cloud-based systems have transformed information management, they face severe limitations related to storage density, energy consumption, maintenance costs, and long-term preservation. Researchers have, therefore, begun exploring biological systems as alternative information storage platforms. Among these, bacteria have emerged …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article
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A Study on Security Requirements of IOT
Abstract: In terms of speed, internet technologies have surpassed traditional technologies. Although the Internet's explosive growth has allowed it to reach its full potential, there are several security dangers associated with it. Many consumer-grade IoT devices are not designed with robust authentication protocols, making them easy targets for hackers. To address this, stronger multi-factor authentication (MFA) methods and certificate-based authentication should be implemented to ensure that only legitimate devices gain access …
Published in International Journal of Radio Frequency Innovations · Vol. 3, Issue 1, 2025 · pp. 24–28 Read article
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Monoclonal Antibodies in Next Generation Animal Nutrition: Mapping Nutrient Immune Interaction Networks in Livestock Systems
Abstract: Sustainable livestock production is increasingly constrained by disease pressure, antimicrobial resistance, and declining feed efficiency under intensifying environmental stressors. Conventional nutritional strategies, while essential, remain insufficient to precisely regulate immune function and metabolic resilience. This review explores the emerging role of Monoclonal antibodies as advanced biologics in next generation animal nutrition, with a focus on mapping nutrient immune interaction networks in livestock systems. It synthesizes current knowledge on how nutrients …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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The Intersection of Bioinformatics and Cellular Function in Disease Modeling
Abstract: The integration of bioinformatics and cellular biology has revolutionized our understanding of disease mechanisms, offering unprecedented opportunities to model complex biological systems. Bioinformatics is an interdisciplinary field that merges biology, computer science, and statistics, offering advanced tools to analyze vast biological datasets. Cellular functions, including gene expression, protein interactions, and metabolic pathways, form the foundation of physiological and pathological states. Disruptions in these processes can result in diseases like cancer, …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
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Artificial intelligence-integrated nanobiotechnology for precision medicine, smart diagnostics, and sustainable environmental applications
Abstract: Background: Nanobiotechnology integrates nanoscale materials with biological systems, enabling breakthroughs in drug delivery, biosensing, and environmental monitoring. However, the complexity of biological interactions and the vast parameter space of nano‑bio interfaces limit conventional design. Artificial intelligence (AI) offers powerful tools for modelling, predicting, and optimising these systems.Objective: This review provides a systematic, STM‑compliant overview of AI‑integrated nanobiotechnology across three domains: precision medicine (AI‑optimised nanocarriers, personalised therapeutics), smart diagnostics (AI‑powered nano‑biosensors, …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 2, 2025 Read article
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Organic Farming
Abstract: Organic farming is an agricultural production management system that excludes all synthetic off-farm inputs and instead relies on on-farm agronomic, biological, and mechanical practices. This sustainable approach focuses on methods such as crop rotations, the use of crop residues, animal manures, off-farm organic waste, and mineral-grade rock additives to maintain soil fertility and health. Organic farming also employs biological systems for nutrient mobilization and plant protection, reducing or eliminating the …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 14, Issue 1, 2025 · pp. 1–8 Read article
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Biomaterials and its Role in Dentistry–A Review
Abstract: Increasing success through modern techniques in implantology brought a new transformation in dentistry field to successfully replace missing teeth. To inflate the success rate, regular and continuous attempts are done to improve the materials, techniques for comprehensive understanding of implant behavior to the biological system. Biomaterials used for implants and brought in contact with the biological environment play the most symbolic role in the success of treatment modality. This has …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 339–352 Read article
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Bio-Inspired Membranes in Oral Drug Delivery: A Pathway to Enhanced Permeability and Targeted Therapy
Abstract: Bio-inspired membranes in oral drug delivery represent a significant advancement in pharmaceutical technology, harnessing principles of natural biological systems to improve drug permeability, bioavailability, and targeted release. This review discusses the design, materials, and fabrication techniques used in bio-inspired membranes, with a focus on materials like chitosan, silk fibroin, and synthetic polymers that mimic biological structures. By exploring the mechanisms of drug permeation, such as mucoadhesion and selective permeability, bio-inspired …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 39–52 Read article
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Self Healing Material: An Introduction
Abstract: Self-healing materials have emerged as a transformative innovation for sustainable infrastructure and advanced applications such as wearable electronics and smart transportation systems. These materials possess the intrinsic ability to repair damage autonomously or with minimal external intervention, thereby extending service life and reducing maintenance costs. Inspired by biological systems, self-healing mechanisms are broadly classified into extrinsic approaches, such as microcapsule and vascular networks based healing, and intrinsic mechanisms involving reversible …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 604–611 Read article