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8 articles for “serotype”
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Molecular Docking of Compounds against Dengue Virus Serotype 2 and Prediction of ADME Properties Using Computational Approaches.
Abstract: Objective: Human lives are now seriously threatened by dengue fever, which is brought on by the dengue virus (DENV). It is well known that phytochemicals have a great deal of promise for curing human viral, bacterial, and fungal diseases. The purpose of this research was to develop drugs against the nonstructural protein (NS5) of dengue virus 2 (DENV2).Methods: Five phytochemicals from various medicinal plants were chosen for this research. The …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 1, 2023 · pp. 1–11 Read article
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Global Prevalence of Salmonella-Mediated Gastroenteritis: A Brief Review
Abstract: Salmonella-mediated gastroenteritis, which has a large impact on morbidity and mortality worldwide is a serious public health issue. Millions of instances of gastroenteritis are linked to Salmonella each year, making it the major cause of foodborne sickness worldwide. Salmonella belongs to the Enterobacteriaceae family and is classified as a Gram-negative bacterium. It was named afterAmerican veterinary surgeon Daniel Elmer Salmon (1850–1914). In 2010, the World Health Organisation reported high case …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 10, Issue 1, 2023 · pp. 18–22 Read article
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Assessment of antibody titer distribution against Salmonella enterica among suspected enteric fever patients.
Abstract: Typhoid fever is a global health problem, causing millions of deaths each year. It is an endemic problem in many developing countries including Nepal. Development of exceptional mechanisms for persistence in its host supports its survival and transmission. However, due to a lack of sophisticated labs and adequate funds, difficulties in the estimation of worldwide impact are often encountered. The Widal test is a diagnostic technique extensively employed to identify …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 2, 2023 · pp. 26–33 Read article
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Typhoid Fever: Etiology, Clinical Manifestations, Diagnosis, and Management
Abstract: Typhoid fever is a systemic and potentially life-threatening infectious disease caused by Salmonella enterica serotype Typhi, which primarily spreads through the fecal-oral route via ingestion of contaminated food and water. It continues to be a major global public health concern, particularly in developing and low-resource countries where poor sanitation, inadequate personal hygiene, and unsafe water supplies prevail. The disease is characterized by prolonged high-grade fever, abdominal discomfort, headache, loss of …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 1–4 Read article
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Seroprevalence and Immunity to Dengue Virus Among Women in Punjab: A Public Health Concern
Abstract: Dengue virus (DENV) infection continues to be a public health concern in Punjab, India, where women are at higher risk because of socioeconomic factors. This cross-sectional study sought to assess the DENV seroprevalence, their neutralizing antibody profiles, and the risk factors associated with DENV among a sample of 1,200 women (aged 18–50 years) in Punjab. Serum samples were processed by IgG/IgM ELISA, and plaque reduction neutralization tests (PRNT90) were done …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 1, 2026 · pp. 6–10 Read article
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Assessment of Animal Trials Conducted on Protectivity of Potential Sub-unit and Recombinant Vaccines against Pasteurella multocida B:2
Abstract: Haemorrhagic septicaemia, caused by Pasteurella multocida serotypes B:2 and E:2, is an acute, fatal and septicaemic disease of bovines occurring as catastrophic epizootics in most tropical regions of Asia and Africa. As chemotherapeutic treatment of P. multocida infections is expensive and ineffective, prevention of disease outbreaks following immunization is the most potent tool. Although, various vaccine formulations as alum precipitated, oil adjuvant, multiple emulsion and live attenuated vaccines are currently …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 2, 2016 · pp. 1–12 Read article
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Seroprevalence of Dengue Viral Infection in Patients Attending To a Tertiary Care Hospital in Kota, South–East Rajasthan, India
Abstract: Background: Dengue virus (DENV) is the most important cause of mosquito-borne viral disease in humans world-wide. Dengue fever is caused by four serotypes of dengue virus (DENV)-DENV1, DENV2, DENV3 and DENV4 .Infections is transmitted mainly by Aedes aegypti. In India, a dengue virus infection has been frequently encountered in epidemic proportions in several states. Objectives: This study was conducted to report the seroprevalence of Dengue virus infection in South-East Rajasthan. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 10, Issue 1, 2020 · pp. 1–9 Read article
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The Detection of Virulence Associated Genes of E. coli O157:H7 by Multiplex PCR
Abstract: An easy and quick system is desirable to detect toxin-producing strains in view of the importance E. coli serotype O157:H7 in human diseases. We report standardization of a multiplex polymerase chain reaction (mPCR) test for simultaneous identification of four significant genes related with the life form E. coli O157:H7 viz, stx 1, stx 2, eae A, hly. An alongside an internal amplification control (IAC). The mPCR technique created in the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 3, 2019 · pp. 21–25 Read article