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12 articles for “sequence alignment”
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Tools and Techniques for Whole-Genome Alignments
Abstract: The prediction of evolutionary relationships between two or more genomes at the nucleotide level is known as whole-genome alignment (WGA). It possesses characteristics of both gene orthology prediction and collinear sequence alignment. WGAs are useful for genome-wide analyses like phylogenetic inference, genome annotation, and function prediction. So many solutions have been developed despite the fact that this problem is difficult. This article provides an overview of the approaches used to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 2, 2022 · pp. 36–38 Read article
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Leucoanthocyanidin Reductase (LAR) Gene Analysisin Reductase
Abstract: Leucoanthocyanidin reductase (LAR) catalyzes the synthesis of catechin that is first step in PA biosynthesis. LAR involved in production of the flavan-3-ol. LAR gene is involved in proanthocyanidine production in several plants. Proanthocyanidins are plant secondary metabolites and occur in a wide range of plants and play an important role in defense against herbivores. The analysis of 50 proteins by global alignment of EF148325 with other ortholog sequences which have …
Published in Research and Reviews : A Journal of Immunology · Vol. 3, Issue 2, 2013 · pp. 15–27 Read article
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Performance Analysis of DNA Sequencing Using Smith-Waterman Algorithm on FPGA
Abstract: The Smith-Waterman algorithm is the most accurate and optimal alignment algorithm for DNA sequencing. It is utilized to locate the ideal local alignment between two sequences. While looking sequence databases that may contain billions of sequences, this algorithm turns out to be computationally costly and tedious. Smith-Waterman algorithm needs additional memory space and this constrains the extent of a sequence to be aligned. In this study we will implement the …
Published in Journal of VLSI Design Tools and Technology · Vol. 9, Issue 2, 2019 · pp. 8–12 Read article
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Genetic Authentication of Acacia Senegal (L.) Wild
Abstract: A study was carried out to ascertain the taxonomic identity and phylogenetic lineage of three presumed Acacia senegalensis using molecular markers. Three (3) varieties of seeds presumed to belong to Acacia spp. were collected from the Rubber Research Institute of Nigeria (RRIN) Benin City and three BP haplotypes (A, B, and C) was used as control for the analysis. These seeds were processed at the Applied Biotech International Laboratory Nigeria …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 33–39 Read article
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To Find the Nucleotide and Protein Sequence of AMYLASE in Homo Sapiens in FASTA Format
Abstract: Comprehensive analysis of current enzymes with α-amylase activity (AAMY) belonging to family 13 of glycoside hydrolases (arrangements of 144 archaea, bacteria, and eukaryotes from different species of GH13; 87). Offers. This study aims to deepen our knowledge of the evolutionary molecular relationships between the sequences of the A and B domains, with a particular focus on the correlation between what is observed in structure and the evolution of proteins. A-domain …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 3, 2021 · pp. 13–15 Read article
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Differential Gene Expression Analysis of Human Atrial Fibroblasts Reveals Dysregulation of RNA Metabolism and Translational Machinery in Atrial Fibrillation
Abstract: Atrial fibrillation (AF) is a complex cardiac arrhythmia characterized by extensive structural remodeling and the activation of atrial fibroblasts, which drive the progression of fibrosis. To identify the underlying transcriptomic alterations, we analyzed six human atrial fibroblast RNA-Seq datasets (three control and three AF) retrieved from the Sequence Read Archive. After performing rigorous quality control and adapter trimming, we aligned the reads to the GRCh38 human reference genome using a …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 · pp. 15–25 Read article
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Electromagnetic Propulsion Train for Future Transportation
Abstract: The Electromagnetic Propulsion Train project focuses on the development and analysis of a prototype system that achieves linear motion through the application of controlled electromagnetic forces. Unlike conventional railway systems that rely primarily on mechanical drive mechanisms such as wheels, axles, and traction motors, this project explores an alternative propulsion approach based on electromagnetic interaction. In this system, a sequence of electromagnets is strategically positioned along the track to generate …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 2, 2025 · pp. 25–31 Read article
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Veterinary Mycology: Fungal Infections in Livestock and Companion Animals
Abstract: Fungal infections represent a significant yet often underestimated challenge in veterinary medicine, affecting both livestock and companion animals. Veterinary mycology encompasses a diverse group of pathogens, including yeasts, molds, dimorphic fungi, and dermatophytes, that can cause localized or systemic diseases with substantial health, economic, and zoonotic implications. In livestock species, such as cattle, sheep, goats, poultry, pigs, horses, and camels, fungal infections manifest as dermatophytosis, mycotic mastitis, aspergillosis, keratomycosis, and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 3, 2025 · pp. 44–51 Read article
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Communication Pathways and Project Success: Analyzing Stakeholder Coordination Impacts on Construction Outcomes
Abstract: It is very critical to have effective communication and coordination among stakeholders for the successful delivery of the projects. Effective communication keeps stakeholders well-informed about project progress, promoting transparency, trust, and collaboration. Coordination ensures that responsibilities and resources are efficiently allocated, reducing the risk of misunderstandings and enhancing decision-making processes. Inadequate stakeholder engagement can lead to confusion, delays, rework, and the failure to meet key project milestones. The impact of …
Published in Journal of Construction Engineering, Technology & Management · Vol. 15, Issue 3, 2025 · pp. 104–126 Read article
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Sequence analysis, DNA Methylation and Molecular therapy of Oral cancer caused by Human Papilloma Virus
Abstract: DNA methylations with oral cancer are been associated with high-risk Human Papillomavirus (HPV) and Epstein-Barr Virus (EBV) onco-proteins interactions may cooperate to increase disease severity. The work focused on human papillomavirus strain 16, a high-risk, sexually transmitted responsible for 95% of all cervical cancers and a large portion of oropharyngeal cancers. The prediction of genes from has shown seven genes from HPV16 strain. Based on gene identification studies, Human papilloma …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 · pp. 1–9 Read article
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Unveiling Actionable Pathogenic Genes for Precision Oncology in Brain Cancers: Glioblastoma and Astrocytoma
Abstract: Glioblastoma (GBM) and astrocytoma are aggressive primary brain tumors characterized by significant molecular heterogeneity, complicating effective treatment. This study employed targeted next-generation sequencing of 529 cancer-associated genes on matched tumor-normal pairs from GBM and astrocytoma patients. Somatic variants were identified using a rigorous bioinformatic pipeline adhering to GATK Best Practices, with variant allele frequencies (VAF) calculated to assess clonal dominance. Functional annotation and driver mutation classification were performed using Ensemble …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 2, 2026 · pp. 43–59 Read article
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Harnessing Deep Learning to Explore Microbial Community Structure and Carbon Storage Capacity in Mangrove Ecosystems: A Framework for Computationally
Abstract: Mangrove ecosystems represent one of the most efficient natural carbon sinks on Earth, functioning as critical blue carbon habitats that sustain diverse microbial communities responsible for biogeochemical cycling and long-term carbon storage. Despite their global ecological significance, accurately quantifying and predicting carbon sequestration in mangrove systems remains challenging due to the complex interactions between microbial diversity, sediment chemistry, and environmental drivers. This study presents a comprehensive and sustainable artificial intelligence …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 · pp. 41–49 Read article