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409 articles for “phytochemicals”
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Exploring Potential Phytochemicals for Myasthenia Gravis Treatment: A Molecular Docking and ADME Analysis Approach
Abstract: Objective: Muscle feebleness and exhaustion derived from a disruption in neuromuscular transference are hallmarks of the crippling autoimmune disease myasthenia gravis (MG). The drawbacks of the current MG therapy options are frequently partial efficacy and adverse effects. To investigate the potential of phytochemicals in MG control, in this work we integrated molecular docking with ADME (absorption, distribution, metabolism, and excretion) analysis using a computer method. We identified molecules exhibiting favorable …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 1–13 Read article
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Comparative Analysis of Bioactive Phytochemical Profiles of Moringa Oleifera and Aegle Marmelos Grown in Bundelkhand
Abstract: A comparative analysis of the bioactive phytochemical profiles of Moringa oleifera and Aegle marmelos grown in the Bundelkhand region was conducted to explore their potential health benefits. These properties make healing plants valuable in herbal medicine, supporting various aspects of health and well-being. The study aimed to determine the differences in the concentrations of bioactive compounds such as phenolic, flavonoids, alkaloids, and vitamins C and E in the leaves and …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 14–24 Read article
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Phytochemical and Pharmacological Importance of Turmeric (Curcuma longa): A Review
Abstract: Curcuma longa L. is a member of the ginger family (Zingiberaceae) and used widely by the traditional medical practitioners for the treatment of various ailments. Due to high curcumin content Indian turmeric is very popular as compared to other countries. Rhizomes derived from Curcuma longa is commonly known as Haldi or Turmeric. Rhizomes are horizontal underground stems that send out shoot as well as roots. Turmeric constitutes of fat-soluble, polyphenolic …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 1, 2019 · pp. 16–23 Read article
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Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article
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Therapeutic Potential of Plant-Derived Phytochemicals in Targeting Receptor Pathways Related to Non-Enzymatic Glycation: A Meta-Analysis
Abstract: Background: Non-enzymatic glycation, where reducing sugars react with proteins, lipids, and nucleic acids, contributes to various pathological conditions, such as diabetic complications and cardiovascular diseases. This process is facilitated by the receptor for advanced glycation end-products (RAGE), which is pivotal in driving inflammation and causing tissue damage. Objective: This meta-analysis evaluates the effects of plant-derived phytochemicals on RAGE expression and associated signaling pathways, assessing their therapeutic potential in glycation-related diseases. …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 60–73 Read article
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Extraction of Phytochemicals from Leaves of Hibiscus rosa sinensis
Abstract: Hibiscus rosasinensis is medicinal and ornamental plant species belongs to Malvaceae family. It contains various phytochemical constituents like phenolic compounds, flavonoids, tannins, alkaloids, saponins etc. Hundreds of chemical compounds are synthesised in different parts of the plant including flowers, stems, roots and leaves etc. that have numerous medical and pharmacological applications. Leaves are used to treat blood vessel hypertension, fatigue, depression and skin problems. It shows various medicinal properties like …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 10, Issue 3, 2020 · pp. 9–11 Read article
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Allelopathy Effect of Phytochemicals in Laticiferous Species Sarcostemma brunonianum Wight & Arn and Ficus tsjakela Burm. f on Vegetative Growth of Sorghum bicolor (L.) Moench
Abstract: The present experimental work was focused out to determine phytochemicals of two medicinal laticifers Sarcostemma brunonianum and Ficus tsjakela and to check the allelopathy potential on Sorghum bicolor under in vitro conditions. Allelochemicals are phytocompounds excreted during the process of secondary metabolism. Chemical components may occur in leaves, stem, root, latex, rhizomes, flowers, fruits, seeds and even in pollen grains. Plant latex supports defense in milk yielding plant species. The …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 43–50 Read article
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Screening of Phytochemicals and Antibacterial Potential of Dicranopteris linearis (Burm.f.) Underw.
Abstract: The present study deals with screening of phytochemical and antibacterial potential of terrestrial fern Dicranopteris linearis (Burm.f.) Underw. collected from Marthandam region of Kanyakumari district of Tamil Nadu, India. The fresh plant material was collected and shade dried for a week and powdered. The powdered material was subjected to gradient extraction with Soxhlet apparatus with two different solvents (acetone and chloroform) and screened for its phytochemical and antibacterial potential. Phytochemical …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 10, Issue 3, 2020 · pp. 1–5 Read article
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A Review on Phytochemical, Pharmacological and Unani Medicinal uses of mur (Commiphora myrrha)
Abstract: In the last few decades the use of plant products in medicines is getting popularized as the herbal medicines are usually cheap, easily available and have higher safety margins and lesser or no side effects due to natural origin. In Unani system of medicine mur (Commiphora myrrha) is mentioned as plant having medicinal properties on various system of human body. Various alkaloids have been identified in phytochemical analysis as well …
Published in Research & Reviews : Journal of Herbal Science · Vol. 9, Issue 1, 2020 Read article
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Preliminary Phytochemical and Acute Toxicity Studies of Different Extracts of Guiera Senegalensis
Abstract: The leaf of Guiera senegalensis is used in the management of many diseases in Nigeria and many African countries, but the medial lethal doses (LD50) of its different extracts are not widely investigated. To evaluate the phytochemical constituents and acute toxicity indexes of aqueous, hexane, dichloromethane and methanol leaf extracts of G. senegalensis, basic phytochemical screening methods were applied. While up and down procedure and Lorke’s method was used for …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 6, Issue 3, 2019 · pp. 11–16 Read article
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Pharmacognostical and Phytochemical Study ofAdhahapushpi (Trichodesma Indicum Linn. R. Br.)
Abstract: Objective: To carry out pharmacognostical and phytochemical studies on each part of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) belonging to the family Boraginaceae. Methods: The root, leaf, stem, flower and fruits of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) were assessed for pharmacognostical studies such as macroscopic, microscopy, powder study, and quantitative microscopy. The powder was assessed for proximate analysis like ash value, extracting value, moisture content, elemental analysis, and preliminary …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 8, Issue 4, 2021 · pp. 28–44 Read article
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Molecular Docking Studies of Wildtype P53 with Damnacanthal and Scopoletin- Phytochemicals Derived from Morinda Citrifolia
Abstract: Cancer is a prominent cause of mortality globally, and it has the potential to impact any region of the body. The tumor suppressor protein P53 plays a significant role in inhibiting tumor growth by regulating DNA repair, inducing cell cycle arrest, promoting senescence, and triggering apoptosis when confronted with genotoxic stress. P53 is found mutated in 50% of cancers where it loses its tumor suppressive properties and gains oncogenic properties …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 20–31 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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In-silico screening of phytochemicals for identification of an alternative therapy for thyroid cancer
Abstract: Thyroid cancer remains a significant health concern globally, necessitating the exploration of novel therapeutic alternatives to improve treatment outcomes. This study targets COT kinase (Cancer Osaka Thyroid Kinase), a protein implicated in the progression of thyroid cancer, using molecular docking methods with various phytochemicals to identify potential therapeutic compounds. PyRx and Discovery Studio were employed to evaluate the interactions and binding affinities of a diverse set of natural compounds with …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 31–55 Read article
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Comprehending Ancient Wisdom of Ayurveda: Unveiling Phytochemistry and Molecular Mechanisms of Rasayana Medicine
Abstract: Rasayana medicine is an integral part of ancient medical system of India. In Sanskrit ‘rasayana’ refers to “path of essence” and serves as one of the eight clinical specialties of classical Ayurveda. Rasayana focuses on restoring health by replenishing vital fluids of human body. According to Ayurveda, our physical body constitutes of seven dhatus called ‘Sapthdhatu’, sapth-seven and dhatu-tissues or microchannels. These channels are the pathway through which vital nutrients …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 59–67 Read article
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Phytotherapeutic Potential of Melaleuca: An Integrative Review of Phytochemistry and Antimicrobial, Antifungal, Antioxidant, and Antiviral Mechanisms
Abstract: Melaleuca alternifolia and other species of the Melaleuca genus stand out for the broad spectrum of pharmacological properties attributed to their bioactive compounds, such as monoterpenes, sesquiterpenes, flavonoids, and polyphenols. This study aimed to critically review and analyze scientific evidence produced between 2005 and 2025 regarding the antimicrobial, antifungal, antioxidant, and antiviral activities of Melaleuca, correlating its phytochemistry with molecular mechanisms of action. For this purpose, an integrative literature review …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 · pp. 16–30 Read article
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Pharmacognostical and Phytochemical Study of- Adhahapushpi (Trichodesma Indicum Linn. R. Br.)
Abstract: Objective: : To carry out pharmacognostical and phytochemical studies on each parts of of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) belonging to the family Boraginaceae. Methods: : The root, leaf, stem, flower and fruits of of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) were assessed for pharmacognostical studies such as macroscopic, microscopy, powder study, and quantitative microscopy. The powder was assessed for proximate analysis like ash value, extracting value, moisture content, …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 8, Issue 2, 2021 · pp. 21–37 Read article
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Studies on Phytochemical analysis of Citrus sinensis
Abstract: Citrus sinensis, also known as sweet orange, is an extensively grown fruit with extensive nutritional and medicinal significance. The present study focussed on the phytochemical analysis of C. sinensis, aiming to identify and quantify the bioactive compounds present in its various plant parts. The investigation encompassed the extraction, isolation, and characterization of secondary metabolites, including flavonoids, alkaloids, terpenoids, phenolic compounds, and essential oils. The research employed a combination of classical …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 13, Issue 3, 2023 · pp. 9–14 Read article
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Phytochemical Screening and the Effect of Temperature Treatment on the Extraction Yield of Phenolic Compounds and the Antioxidative Activities of Two Medicinal Species Growing in Algeria: Ammi visnaga and Mentha pulegium
Abstract: The aims of this investigation are the identification of molecules of secondary metabolism and study the impact of two extraction techniques (extraction by boiling water under reflux and maceration in 70% hydroethanolic solution at ambient temperature) on the yield of phenolic compounds and the antioxidative activity on two species widely used in Algeria as medicinal plants; Ammi visnaga and Mentha pulegium. The results show that phytochemical screening indicates the presence …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 5, Issue 3, 2018 · pp. 18–25 Read article
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Phytochemical Profile & Therapeutic Potential of Clematis Terniflora: A Comprehensive Review
Abstract: Clematis terniflora is a plant comes under the family Ranunculaceae, which is folk medicinal plant which is found widely in China, according to the Chinese medical system, Clematis terniflora is a widely distributed folk remedy that is used to cure rheumatoid arthritis, asthma, syphilis, gout, malaria, dysentery and used as analgesic, antitumor, anti-inflammatory, diuretic, antibacterial, antioxidants and anti-inflammatory etc. It is distributed around the world like China, Japan, Korea, Mongolia, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 16–24 Read article