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35 articles for “pharmacology”
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A Review on Phytochemistry and Pharmacology of Macaranga peltata
Abstract: Macaranga peltata, categorized within the Euphorbiaceae family, represents a prevalent pioneer arboreal species across Southeast Asia, specifically in regions such as India and Sri Lanka. This review scrutinizes the phytochemical properties and pharmacological profiles of Macaranga peltata, underscoring both its historical medicinal applications and prospective therapeutic roles. The plant exhibits a rich composition of secondary metabolites, encompassing flavonoids, stilbenes, tannins, and terpenes, with the majority of these compounds being extracted …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 50–59 Read article
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Pharmacological evaluation of Hepatoprotective activity of Indian medicinal plants Cordia Myxa and Canscora diffusa on wistar albino rats
Abstract: Two plants (Cordia myxa and Canscora diffusa), which were claimed to possess hepatoprotective activity, were selected. The Selected plants were authenticated by an expert botanist. In the current study, herbal extraction involving solvents of decreasing polarity (petroleum ether, ethyl acetate, and hydroalcoholic) was used to extract bioactive compounds from the plants of Cordia Myxa and Canscora diffusa in polyherbal preparations. A phytochemical evaluation was performed, including an acute toxicity study …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 31–44 Read article
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What Nurses Should Know About New Ways to Treat Muscle Pain
Abstract: Muscle discomfort is a common clinical concern that can significantly limit mobility, functional ability, and overall quality of life. Recent advancements in assessment and management strategies have enabled nurses to deliver more precise, evidence-based care for patients experiencing muscular pain. Emerging diagnostic approaches now include enhanced screening scales that offer greater sensitivity in identifying pain patterns, as well as digital monitoring tools that allow continuous evaluation of symptoms across care …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 12–17 Read article
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Exploring the properties and extraction of neem leaves
Abstract: Neem (Azadirachta indica) is a versatile medicinal plant, for its diverse therapeutic properties. This abstract provides a comprehensive overview of recent research focusing on phytochemical analysis, biochemical characterization, and antimicrobial susceptibility testing of Neem extracts. Utilizing the different from of chemical used in it, phytochemical analysis identified a plethora of secondary metabolites within Neem, including alkaloids, flavonoids, terpenoids, steroids, saponin, tannins, quinone, and phenolic compounds, indicative of its complex chemical …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 32–39 Read article
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The Role of Natural Products in Antiviral Drug Discovery: Insights into Mechanisms and Therapeutic Potential
Abstract: Drug discovery has always relied heavily on natural sources, especially when it comes to creating antiviral medications. This review explores the therapeutic potential of various natural products, including plant extracts, marine compounds, and microbial metabolites, in the fight against viral infections. We examine the mechanisms of action by which these natural compounds exert their antiviral effects, including direct inhibition of viral replication, modulation of host immune responses, and interference with …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 36–47 Read article
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A Comprehensive review on phytomedicinal activity of chirchita (Achyranthes aspera): an Indian Rural Medicinal Plant
Abstract: Because it is used to treat many types of diseases. Native to India, Achyranthes aspera (Chirchita) has been used in rural medicine for generations.This review explores the phytomedicinal significance of Achyranthes aspera, focusing on its bioactive compounds and the pharmacological activities that support its use in treating various ailments. This plant is a useful tool in traditional and alternative medicine. Because it has anti-inflammatory properties Antioxidants Antibacterial, anticancer and liver …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 74–85 Read article
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Integrating Horticultural Techniques for the Propagation of Ethnomedicinal Pteridophytes in the Himalayan Region
Abstract: The Doon Valley, including the regions of Dehradun, Mussoorie, and Chakrata in Uttarakhand, India, is rich in ecological and medicinal plant diversity. This study focuses on the geographical distribution, habitats, and medicinal applications of 28 pteridophyte species found in these regions. Detailed field observations and data collection from various scientific journals, databases, and publications have contributed to understanding the traditional and pharmacological uses of these plants. The results show that …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 2, 2024 · pp. 1–19 Read article
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Risk & Opportunities in Development of new Drugs: A New Perspective
Abstract: The procedures of drug discovery and development are briefly described in this article. Our goal is to assist researchers whose work may be pertinent to the discovery and/or development of new drugs in framing their research reports in a way that appropriately situates their findings within the drug discovery and development process and supports the efficient translation of preclinical research to humans. One overarching theme of our article is the …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 19–28 Read article
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Molecular Docking studies of Benzodiazepine Derivatives With GABA(B) Receptor
Abstract: Benzodiazepines (BZDs) are pharmacologically significant compounds that act by binding to GABA A neurotransmitter receptors, subsequently augmenting GABA-induced chloride ion flux, consequently inducing neuronal hyperpolarization. Benzodiazepines are commonly used in the treatment of sleep disorders, anxiety, muscle spasms, seizure disorders, and some forms of depression. The primary inhibitory neurotransmitter, GABA, functions on two types of receptors: the ligand-gated GABA A/C receptors and the G protein-coupled GABA B receptors. These neurotransmitters …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 1–14 Read article
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A Factualistic Study of Phytomedicinal Activity of Curcuma longa (Haldi): Plant That Infuses Life
Abstract: Curcuma longa, commonly known as turmeric, is a plant of remarkable medicinal significance that has been utilized for centuries in traditional medicine and has garnered considerable attention in modern scientific research. This review explores its extensive phytomedicinal potential, focusing on the plant's bioactive compounds, particularly curcumin, which is recognized as the primary agent responsible for its therapeutic properties. Turmeric contains an array of chemical constituents, including curcuminoids, volatile oils, and …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 14–24 Read article
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A Comprehensive Review of Alternative Medicine: Biological Plausibility, Testability, Repeatability, and Effectiveness
Abstract: Alternative medicine, encompassing practices, such as acupuncture, herbal remedies, homeopathy, chiropractic care, Ayurveda, and Traditional Chinese Medicine (TCM), has gained global popularity as patients seek non-conventional healthcare solutions. Despite its widespread use, scientific evaluation of its biological plausibility, testability, repeatability, and effectiveness remains a significant challenge. This review critically examines these four criteria to assess the validity and reliability of alternative therapies. Acupuncture demonstrates partial plausibility, with evidence suggesting its …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 32–46 Read article
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“Review Article on Tridax Procurmbens Herbal Antibacterial Cream”
Abstract: Abstract Tridax procumbens (L.), also referred to as coat buttons or tridax daisy, is a common plant in the Asteraceae family that is well-known for its exceptional pharmacological and therapeutic properties. This plant has long been utilized as an anticoagulant, antifungal, insect repellent, wound healer, and hepatoprotective agent in Indian Ayurveda. With a focus on its medicinal and formulation features, the current study offers a thorough summary of its botanical …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 1, 2026 · pp. 21–29 Read article
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The Hidden Struggle: Premenstrual Depression its Impact on Women’s Health and Management Strategies: A Narrative Review.
Abstract: Background: Premenstrual depression, including Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD), represents a significant yet underrecognized contributor to women’s mental health burden. Hormonal fluctuations during the luteal phase interact with neurotransmitter systems, particularly serotonin and GABA, leading to affective and somatic symptoms that impair daily functioning. Objective: This systematic review synthesizes evidence on the prevalence, pathophysiology, psychological impact, and management strategies of premenstrual depression among reproductive-aged women, with particular …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 · pp. 21–32 Read article
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Unveiling the Role of Lead Molecules in CADD: A Systematic Review
Abstract: The word "medicate plan" alludes to the objective creation of modern drugs. Arbitrary screening of engineered compounds, engineered of organically dynamic compounds based on actually happening drugs, amalgamation of basic analogs of actually happening lead particles, and usage of the bioisosteric hypothesis are a few of the strategies that have been utilized. As a result, the most recent drift in medicate plan is to either completely enhance a lead or …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article
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A Review of Different Polymer and Plasticizers
Abstract: Plasticizer and polymer are essential components in the pharmaceutical industry, especially when creating both cutting-edge and conventional drug delivery systems. The differences between synthetic, semi-synthetic, and all-natural polymers are examined in this review to highlight their diverse qualities and uses. When designing drug delivery systems to target areas, the choice of polymer is crucial. Because of their repeatability and adaptability, synthetic polymers are widely used in the creation of precision …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 1–7 Read article
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Diversity of Agaricaceae (Basidiomycota: Agaricales) in Dharampur and Kaprada Taluka, Valsad District: A Taxonomic Study
Abstract: The fungal diversity of Dharampur and Kaprada Taluka in Valsad District, Gujarat, India, particularly within the Agaricaceae family, has been extensively studied. According to a standard reference text, the Agaricaceae contains 85 genera and 1340 species. Agaricaceae fungi, categorized as macrofungi, are prevalent in this region and are notably utilized by local tribal communities for culinary purposes due to their edibility. The life cycle of Agaricus is cyclic beginning with …
Published in International Journal of Fungi · Vol. 1, Issue 1, 2024 · pp. 51–62 Read article
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InSilico Analysis and Homology Modeling of Tetrahydroprotoberberine Oxide involved in the Berberine Biosynthesis
Abstract: Objective: Berberine, a bioactive compound found in various plant species, exhibits diverse pharmacological properties with potential applications in pharmaceutical research. The biosynthesis of berberine involves several enzymatic steps, with (S)-tetrahydroprotoberberine oxidase playing a pivotal role. This study aimed to elucidate the structural and functional characteristics of (S)-tetrahydroprotoberberine oxidase to better understand its role in berberine biosynthesis and its potential biotechnological applications. Methods: Using bioinformatics tools and computational methods, the physicochemical …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 7–26 Read article
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Aquatic Ecosystems: A Review on Prospecting of Anticancer Molecules from Fungi & Other Microbes
Abstract: Marine biota; namely, actinomycetes, bacteria, fungi, microalgae, green algae, oceanic weeds, mangroves, and other extremophiles constitute about 90% of the oceanic biomass. The organisms are taxonomically diverse, biologically productive/active, and biochemically unique. These unique biochemiques may act as a great source for the discovery of new bioactive molecules, including anticancer drugs. The marines produce medicinally potent biochemicals; namely, sulfated saccharides, polyphenols, and, sterols. Only a few of these alkaloids have …
Published in International Journal of Fungi · Vol. 1, Issue 2, 2024 · pp. 1–22 Read article
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Flaxseed and Diabetes Management: A Comprehensive Review of Recent Studies and Potential Mechanisms
Abstract: Diabetes mellitus, a condition characterized by chronic hyperglycemia, has become a significant global health challenge, leading to substantial morbidity and mortality rates. Dietary techniques are crucial for the effective control of diabetes, including both pharmaceutical and non-pharmacological therapies. Flaxseed (Linum usitatissimum) is one of the functional foods that has attracted a lot of interest because of its abundance of bioactive components, including lignans, dietary fiber, and alpha-linolenic acid (ALA). The …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 24–32 Read article
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Investigating the Impact of Viral Infections on Pharmacokinetics and Pharmacodynamics of Antiviral Drugs
Abstract: The emergence and re-emergence of viral infections pose significant challenges to public health, necessitating a comprehensive understanding of how these infections impact the pharmacokinetics and pharmacodynamics of antiviral drugs. This review explores the intricate interactions between viral pathophysiology and the pharmacological effects of antiviral agents. Factors such as viral replication dynamics, host immune responses, and the genetic variability of both viruses and hosts significantly influence drug absorption, distribution, metabolism, and …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 23–30 Read article