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6 articles for “paclitaxel”
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Ethanolic Root Extract of Jatropha curcas L. Ameliorates Paclitaxel-Induced Neuropathic Pain in Rats
Abstract: Jatropha curcas is a plant used in various parts of the world as food, medicine for pain and biofuel. The present study investigated the potential analgesic properties of ethanolic root extract of J. curcas on paclitaxel-induced neuropathic pain in rats. Neuropathic pain was induced in rats with paclitaxel. Cold allodynia was measured with cold water at 4.5 °C. Mechanical hyperalgesia was measured in the Randall-Sellito test and thermal hyperalgesia evaluated …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 2, 2013 · pp. 10–15 Read article
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Neuropathic Potential of Cabazitaxel Comparative to Paclitaxel and Ameliorative Effect of Capsaicin
Abstract: Paclitaxel and cabazitaxel both are the cytotoxic anticancer drugs having microtubule damaging property. The study aims at comparative neuropathic potential evaluation of cabazitaxel against paclitaxel and to assess the efficacy level of intraperitoneally applied capsaicin isolated from Capsicum annuum seed against both paclitaxel and cabazitaxel-induced neuropathy. Neuropathy was evaluated of heat hyperalgesia, cold allodynia, tactile mechanical hyperalgesia and extent of motor incoordination and motor impairment development on mice. Alternate day …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 5, Issue 2, 2018 · pp. 25–38 Read article
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Sequence analysis, DNA Methylation and Molecular therapy of Oral cancer caused by Human Papilloma Virus
Abstract: DNA methylations with oral cancer are been associated with high-risk Human Papillomavirus (HPV) and Epstein-Barr Virus (EBV) onco-proteins interactions may cooperate to increase disease severity. The work focused on human papillomavirus strain 16, a high-risk, sexually transmitted responsible for 95% of all cervical cancers and a large portion of oropharyngeal cancers. The prediction of genes from has shown seven genes from HPV16 strain. Based on gene identification studies, Human papilloma …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 · pp. 1–9 Read article
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Targeted Delivery of Nanoparticle Based Taxanes for Breast Cancer Treatment: A Review
Abstract: The most common type of cancers in women is breast cancer. In United States, it is the second common cause of death in women. Metastatic cancer is the advanced stage of breast cancer, which is related to the distribution of cancerous cells from breast tissues to different areas of the body. Over the past numerous years, taxanes are bound to perform a huge role in the management and treatment of …
Published in Trends in Drug Delivery · Vol. 6, Issue 3, 2019 · pp. 36–51 Read article
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A Comprehensive Review of Ethnobotanical Studies on Traditional Indian Herbal Plants for Lung Cancer Management
Abstract: Lung cancer is a leading cause of cancer-related deaths in the world. Current therapies for lung cancer are often limited by many side effects. This review compiles and evaluates ethnobotanical evidence and modern scientific findings of Indian herbal plants traditionally used for respiratory and tumor-related disorders, with a focus on their relevance to lung cancer management. Herbal phytochemicals and how they show their potent activities were also listed in this …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 1, 2026 · pp. 1–7 Read article
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Carbon Nano Tubes: New Techniques for Cancer Treatment
Abstract: Carbon Nano tubes (CNTs) have been recently introduced as a novel carrier system in the biomedical field and produce small and large therapeutic molecules. CNTs have attracted increasing attention for their versatile applications. Based on layers of CNTs, CNTs are generally divided into two categories: single-walled carbon Nano tubes (SWCNTs), multi-walled carbon Nano tubes (MWCNTs). It shows the unique properties and cylindrical shape structure. It shows a greater advantage in …
Published in Trends in Drug Delivery · Vol. 5, Issue 1, 2018 · pp. 28–39 Read article