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1000 articles for “pH indicator”
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Exploring Oroxylum indicum Phytochemicals as VEGFR-2 Inhibitors: A Molecular Docking Approach for Cancer Management
Abstract: Cancer is still a major health problem around the world and is one of the top causes of death. A protein called VEGFR-2 (vascular endothelial growth factor receptor 2) is important because it helps blood vessels grow by supporting the survival, movement, and growth of certain cells. This process is essential for tumors to grow and spread to other parts of the body. This study focused on evaluating the binding …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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Formulation and Evaluation of Aqueous Azadirachta indica Phytosome
Abstract: A phytosome is a complex created through the union of a natural compound, typically a plant extract, with a phospholipid. Phospholipids play a crucial role in cell membranes, possessing a structure comprising a hydrophilic (water-attracting) head and hydrophobic (water-repelling) tails. This distinctive structure enables phospholipids to construct lipid bilayers, fundamental elements of cell membranes. Phytosome increases the bioavailability, and absorption of active chemical constituents in the extract with the help …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 1, 2024 · pp. 17–30 Read article
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In Situ Investigation of Hemidesmus indicus Phytocompound Extracts as a Therapeutic Target for Acute Myeloid Leukemia
Abstract: Objective: Acute myeloid leukemia (AML) is an apoptotic condition in the hematopoietic system induced by the differentiation and maturation of stem cells into erythrocytes, and leukemic cell proliferation is suppressed as the PI3K-Akt-mTOR pathway is pharmacologically targeted with certain inhibitors. As a result, in silico molecular docking of compounds against AML receptors, CTMP, was used in computational research on Hemidesmus indicus to uncover therapeutic phytochemicals for AML. Thus, this study …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 38–53 Read article
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Melanogenic Inhibitory Effects of Sesamum indicum Phytocompounds Towards CDK 2, c-KIT, and BRAF.
Abstract: Objective: Melanoma is thought to be the fifth most frequent cancer in the US population, despite cancer being the most common cause of death in the globe. BRAF, CDK2, and c-KIT proteins are regarded as potential therapeutic agents since mutations in these proteins are the primary cause of melanoma. For the investigation of their pharmacological properties and therapeutic activities against the target proteins, Sesamum indicum L. and its phytocompounds were …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 3, 2023 · pp. 46–61 Read article
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Regression Analysis of Topological Indices and Physicochemical Properties of Polymer-Based Anticancer Drugs
Abstract: The research analyzed the quantitative correlation between topological indices and the physicochemical properties of selected anticancer compounds using regression analysis. Various topological descriptors—such as the First Zagreb Index, Second Zagreb Index, and Forgotten Index were calculated and regressed against key molecular features, including polar surface area, melting point, and molar refractivity. The regression analysis revealed linear correlations between these topological indices and the properties of anticancer drugs, with particularly strong …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 255–267 Read article
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A Review on Pharmacological Activities and Phytochemical Studies of Quisqualis Indica Linn
Abstract: This article contain brief review of pharmacological study and phytochemical study of plant Quisqualis Indica Linn, the point which have to be considered that this plant can be available easily as it is an evergreen plant and most of the people were used to decorate their houses, as this is an ornamental plant too which doesn’t depend on seasons to grow. Quisqualis indica Linn contains phytoconstituents such as trigonelline (alkaloid), …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 11, Issue 2, 2023 · pp. 32–36 Read article
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Preparation of an Indicator Dye from Tender Coconut Husk and Analysis of its Stability
Abstract: India is eminent in its production and usage of tender coconuts. The aim of this paper was to develop a useful product from tender coconut waste. It focuses on the utilization of coconut husk to produce an indicator dye for the detection of the approximate pH of any solution. A concentrated dye was first prepared in aqueous form. When stored, it was stable and functional at room temperature as well …
Published in Research & Reviews : Journal of Botany · Vol. 9, Issue 3, 2020 · pp. 17–23 Read article
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Pharmacognostical and Phytochemical Study ofAdhahapushpi (Trichodesma Indicum Linn. R. Br.)
Abstract: Objective: To carry out pharmacognostical and phytochemical studies on each part of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) belonging to the family Boraginaceae. Methods: The root, leaf, stem, flower and fruits of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) were assessed for pharmacognostical studies such as macroscopic, microscopy, powder study, and quantitative microscopy. The powder was assessed for proximate analysis like ash value, extracting value, moisture content, elemental analysis, and preliminary …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 8, Issue 4, 2021 · pp. 28–44 Read article
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Investigation of Pollution Status in River No. 2, Freetown, Sierra Leone, Using Physicochemical and Bacterial Indicators
Abstract: This study assessed the physicochemical and bacteriological quality of surface water in the River No. 2 watershed, Sierra Leone, through monthly sampling from March–August 2024 at upstream, midstream, and downstream sites. Analyses included temperature, turbidity, pH, electrical conductivity, total dissolved solids, ammonia, fluoride, sulfite, nitrate, lead, arsenic, chromium, and microbial indicators (Escherichia coli, fecal and non-fecal coliforms). Most physicochemical parameters met WHO drinking-water guidelines. pH (7.0–7.3), TDS (7–17 mg/L), turbidity …
Published in International Journal of Pollution: Prevention & Control · Vol. 4, Issue 1, 2026 · pp. 11–27 Read article
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Pharmacognostical and Phytochemical Study of- Adhahapushpi (Trichodesma Indicum Linn. R. Br.)
Abstract: Objective: : To carry out pharmacognostical and phytochemical studies on each parts of of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) belonging to the family Boraginaceae. Methods: : The root, leaf, stem, flower and fruits of of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) were assessed for pharmacognostical studies such as macroscopic, microscopy, powder study, and quantitative microscopy. The powder was assessed for proximate analysis like ash value, extracting value, moisture content, …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 8, Issue 2, 2021 · pp. 21–37 Read article
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Phytochemical Screening of Coccinia indica
Abstract: It is a code of conduct that ensures the correct substances in the correct amount for the desired therapeutic effect such as safety, quality, and efficacy. There have evidence which suggest that Coccinia indica has therapeutic effects that range from antihyperglycaemic and antiureogeniceffects in diabetic, ovicidal and repellent properties. The active principles are extracted from plant drugs and purified for therapeutics. Detection of nature of adulterants carried out by various …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 6, Issue 2, 2019 · pp. 30–38 Read article
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Exploring Azadirachta indica’s Potential to Combat Visceral Leishmaniasis Through GP63 Inhibition
Abstract: Objectives: Millions of people worldwide suffer from the parasite disease visceral leishmaniasis. Determine the naturally occurring active ingredients in Azadirachta indica, which are employed as a disease-prevention agent and have several uses in medicine. To choose the best ligand to use as a medication, absorption, distribution, metabolism, and excretion (ADME) studies and molecular docking are employed. Methods: To obtain the GP63 protein, the Protein Data Bank (PDB) database was accessed. …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 1–12 Read article
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A Review on Pharmacological Activities of Garcinia Indica
Abstract: The plant Garcinia indica having active constituents like xanthones, flavonoids, benzophenones, lactones, and phenolic acids D-Leucine, fukugicide, xanthochymol, isogarcinol, isoxanthochymol, Cambogic acid, HCA, HCA lactone, mangostin, GB-1, GB-2, amentoflavone and garcinol. The plant is screened for Antioxidant and Hepatoprotective activity, Antimicrobial, Cytotoxic Effects, Anti-fungal activity, Anti-neoplastic activity, Anti-bacterial activity, Anti-fungal activity, Anti-bacterial activity, Anti-inflammatory activity, Hypoglycaemic activity, Anti-ulcer activity, Neuroprotective Effects, Anti-obesity activity, Antiaging activity. The present review is therefore, …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 10, Issue 3, 2021 · pp. 16–20 Read article
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Comparative Phytochemical Composition and Antioxidant Activities of Mangifera indica and Mucuna urens Seeds
Abstract: ABSTRACTThis study was carried out to evaluate and compare the phytochemical composition and antioxidant activities of Mangifera indica and Mucuna urens seeds, with a view to elucidating the phytochemical basis for their medicinal uses, and their nutraceutical potentials as soup thickeners. Of the two seeds, M. indica had significantly higher (ρ < 0.05) total phenol, tannin, total flavonoid and total saponin contents than M. urens on dry weight basis. Conversely, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 1, Issue 2, 2012 · pp. 15–24 Read article
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Psychological Profile of Patients Undergoing Hemodialysis and Its Association with Physiological Parameters
Abstract: Background: End-stage renal disease (ESRD) is a chronic, progressive condition requiring maintenance hemodialysis, which imposes substantial physiological, psychological, and social burdens on patients. While physiological indicators are routinely monitored during treatment, the influence of psychological factors on these indicators and patients' quality of life remains inadequately explored, particularly in the Indian context. Objective: To investigate the relationship between psychological variables (depression, anxiety, illness intrusiveness, and quality of life) and physiological …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 · pp. 40–48 Read article
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Stability Indicating HPLC Method for Drugs Indicated for Helicobacter Pylori-associated Ulcers
Abstract: Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 Triple therapy regimen that comprises a proton pump inhibitor likes Omeprazole, antibiotics like Doxycycline and Tinidazole can be used for treatment of peptic ulceration which is caused by H. pylori. A validated HPLC method was developed as a stability-indicating HPLC method for these drugs and its impurities. New method overcame interference between Doxycycline and its epimer on achiral column by using …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 1, 2015 · pp. 28–46 Read article
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Design and Development of an Optical Fiber pH Sensor using an Artificial Neural Network
Abstract: This project presents the development and design of an artificial neural network (ANN) in signal processing of optical fiber pH sensor. The pH sensor has bromophenol blue (BPB) solution as the indicator which is immobilized in a sol-gel thin film as a sensing material. The indicator shows change in color as pH of the solution changes and the spectra of these changes are calibrated to find the pH value. The …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 4, Issue 3, 2013 · pp. 1–6 Read article
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Two New, Useful and Facile Stability-Indicating UV Spectrophotometric Methods for the Determination of Rosiglitazone in Pharmaceuticals
Abstract: Rosiglitazone (ROS) is an antidiabetic drug belonging to the thiozolidine class. Two simple, rapid, sensitive, accurate and reproducible UV-spectrophotometric methods were developed and subsequently validated for the determination of ROS in bulk and tablet form. The methods are based on the measurement of the absorbance of the drug solution either in 0.1 M NaOH (NaOH method) or in 0.1 M HCl (HCl method) at 316 nm in both instances. The …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 2, 2017 · pp. 8–19 Read article
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Extraction and Application of Natural Dye from Nerium oleander
Abstract: The present study involves extraction of dye from Nerium oleander flower using varied percentage (10%, 20%, 5%, 10%) of different solvents and different methods (water bath, sonicator bath, microwave oven and shaker incubator). Extraction with different solvents (distilled water, ethanol, chloroform, methanol) and extraction methods were found to exhibit differential extraction of dye and it was evident by the intensity of dye extract. Absorption maximum of the extracted dye using …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 37–46 Read article
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Phytochemicals from Plectranthus amboinicus and Azadirachta indica for Promoting Angiogenesis and Tissue Regeneration – A Short Review
Abstract: The eco-friendly synthesis of silver nanoparticles (AgNPs) using plant extracts has garnered significant attention due to its potential in biomedical applications. This review highlights the green synthesis methodologies, focusing on Plectranthus amboinicus and Azadirachta indica, their phytochemical components, and their docking studies with angiogenesis-related receptors such as VEGF and FGF. The applications of AgNPs in tissue regeneration, wound healing, and angiogenesis are discussed in detail, emphasizing the roles of phytochemicals …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 2, 2025 · pp. 34–40 Read article