Search
10 articles for “microfluidic diagnostics”
-
Automated Blood Cell Counting and Disease Identification Using Image Processing: Implications for Polymer Composite- Based Biomedical Diagnostic Devices
Abstract: Accurate quantification of blood cells is central to clinical decision-making and to the performance of emerging polymer composite–based diagnostic platforms. This work presents a cost-effective, image-processing pipeline for automated counting of red blood cells (including overlapping cells), white blood cells, and platelets from Leishman-stained peripheral blood smears, and articulates its relevance to polymer composite microfluidic and biosensor devices. Implemented in Python with OpenCV, the workflow performs grayscale conversion, median/Gaussian denoising, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 262–270 Read article
-
How Microfluidics Are Used in Modern Science: Lab-on-A-Chip
Abstract: Microfluidics has changed modern research by making lab-on-a-chip (LOC) technologies that combine multiple lab functions into small, portable devices. These little platforms make it easier to correctly handle small amounts of fluid, which saves time, money, reagents, and automation. This article talks about microfluidics and how it helps LOC technology go forward in all areas of science. We look at important uses of biomedical diagnostics, drug development, environmental monitoring, and …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 2, 2025 · pp. 35–48 Read article
-
Extracellular Vesicle-Based Liquid Biopsies: Decoding the Tumor Microenvironment for Precision Oncology
Abstract: The tumor microenvironment (TME) plays a pivotal role in cancer initiation, progression, and therapeutic response. Decoding the TME is, therefore, essential for advancing precision oncology. Extracellular vesicles (EVs), including exosomes and microvesicles, are nanoscale lipid bilayer particles secreted by tumor and stromal cells. They transport a wide range of bioactive molecules, such as DNA, RNA, proteins, lipids, and metabolites, which reflect the dynamic state of the TME. Recent advances in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 43–62 Read article
-
Precision in Progress: The Crucial Nexus of Instrumentation and Measurement in Biotechnology Advancements
Abstract: This comprehensive review examines the critical importance of instrumentation and measurement technologies in enabling advances across diverse domains of modern biotechnology. Detailed examples are provided demonstrating how analytical tools empower quantitative biology, drive discoveries, catalyze innovations, and provide solutions to global challenges. The historical evolution of bioanalytical techniques is traced, highlighting milestones that unleashed new capabilities. Current trends and future outlook are explored, underscoring the ongoing pivotal need for precision …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 11–19 Read article
-
Role of Fluid Engineering in Biomedical and Healthcare Systems: A Comprehensive Review
Abstract: Fluid engineering — the study and application of fluid behavior, transport, and interaction — has become a cornerstone of modern biomedical and healthcare systems. This review synthesizes the multifaceted roles fluid engineering plays across diagnostics, therapeutics, biomedical devices, and physiological modeling. Micro-fluidics enables precise manipulation of microliter and nanoliter volumes, facilitating rapid point-of-care diagnostics, high-throughput screening, and the fabrication of uniform nano particles for targeted drug delivery. In cardiovascular medicine, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–5 Read article
-
Explainable Machine Learning Integrated with Polymer-Based Diagnostic Technologies for Liver Health Classification
Abstract: Early and reliable assessment of liver health is essential for timely treatment, yet most machine-learning approaches face limitations such as class imbalance and low clinical interpretability. This study proposes a polymer-integrated, explainable machine-learning framework that combines SMOTE-based data balancing, Logistic Regression, and XAI techniques (SHAP and LIME) for transparent liver-health classification. In addition to ML modelling, the study emphasizes the emerging role of polymer-based biosensors, microfluidic polymer chips, polymer nanomaterials, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 631–643 Read article
-
A Study on Automatic Feedback Control by Image Processing for Mixing Solutions in a Microfluidic Device
Abstract: Precise and rapid mixing of chemical and biological reagents is a critical yet challenging aspect of microfluidic systems, often limited by laminar flow conditions and the need for manual or pre- programmed interventions. Existing mixing strategies frequently lack real-time adaptability and closed-loop control, hindering reproducibility and the execution of complex reaction protocols. This work presents an innovative automatic feedback control system utilizing the study on real- time image processing to …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 2, 2025 · pp. 32–41 Read article
-
Electromechanical Modeling of Microscale Fluidic Systems with Electro Kinetic
Abstract: Due to their capacity to carry out complex fluid manipulations at the microscale, microfluidic systems have become more popular in a variety of applications. For a variety of industries, including biomedical diagnostics, chemical analysis, and environmental monitoring, achieving precise and effective fluid control is essential. The electromechanical modeling of microscale fluidic systems using electro kinetic actuation is the main topic of this research study. We propose a thorough framework for …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 1, Issue 1, 2023 · pp. 18–22 Read article
-
A Comprehensive Review on Male Infertility
Abstract: The failure to attain a clinical pregnancy naturally after one year of unprotected intercourse is termed as infertility. Some of the factors that contribute to Infertility are late marriages, advanced age, genetics and lifestyle to name a few. To tackle this scenario, infertile and sub fertile couples take the aid of assisted reproductive technology. Intra uterine insemination (IUI), In vitro fertilization (IVF), Intra cytoplasmic sperm injection (ICSI), surgical sperm retrieval …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 95–103 Read article
-
Modern Chemistry & Chemical Technology in Sensor Formation
Abstract: The field of sensor formation stands at the vibrant intersection of modern chemistry and chemical technology, driven by an insatiable demand for precise, rapid, and sensitive detection across myriad applications. This paper explores the foundational and transformative role these disciplines play in engineering next-generation sensing platforms. Modern chemistry, through its atomic-level precision in synthesizing novel responsive materials – ranging from advanced polymers and supramolecular architectures to cutting-edge nanomaterials like graphene, …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 1–9 Read article