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44 articles for “hypothesis”
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Neuro-Symbolic Agentic AI for Autonomous Scientific Discovery: Integrating Deep Reinforcement Learning, Quantum Simulation, and XAI-Audited LLM Hypothesis Generation in Drug Target Identification
Abstract: The exponential growth of multi-omics data and the increasing complexity of disease-associated protein interactomes have rendered conventional drug target identification pipelines computationally and epistemologically inadequate. This paper presents the Neuro-Symbolic Agentic AI for Scientific Discovery (NS-AASD) framework, a unified architecture that cohesively integrates deep reinforcement learning (DRL) exploration strategies, variational quantum simulation (VQS) of protein conformational dynamics, and XAI-audited large language model (LLM) hypothesis generation within an autonomous scientific discovery …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 2, 2026 Read article
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Conceptual Framework and Hypothesis Development for Green Supply Chain Practices
Abstract: In recent decades, sustainability has gained significant attention. Green Supply Chain Management (GSCM) ensures that corporate and governmental initiatives effectively make operations more environmentally friendly, increase market share, enhance brand recognition, and boost profitability. Sustainable or "green" supply chain management integrates both financial and environmental objectives into the strategy for managing supply chain operations. This integration helps reduce carbon footprints while improving profitability and financial returns. GSCM encompasses various aspects, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 64–78 Read article
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Introduction to Statistical Tests of Significance
Abstract: Hypothesis examination is the process in which we compare between two differing hypotheses. i.e. the null hypothesis H0 and the alternative hypothesis. As the null hypothesis is examined, a choice is either correct or incorrect. An incorrect conclusion can be produced in two methods: We can deny the null hypothesis once it is true (Type I error) or we cannot succeed to eliminate the null hypothesis when it is incorrect …
Published in Research & Reviews : Journal of Statistics Read article
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An Insilico Study of Isobutrin and Phosphorylase Kinase - A Ray of Hope for Psoriasis Patients – Clinical Hypothesis
Abstract: Psoriasis is a chronic, hyper-proliferative and inflammatory skin disease. Increased levels of the calmodulin-containing enzyme, namely, phosphorylase kinase (PhK), were observed in the human epidermis of the active psoriasis cases. Thus PhK is a potential biomarker for the diagnosis and progression of the skin disease, namely, psoriasis. The search for the potential molecules that could supress the over expression of PhK is underway and any break-through in this direction leads …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 1–8 Read article
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Butrin Tackles Retinoblastoma – A Clinical Hypothesis †
Abstract: Breach of association of legumain protein activities to the corresponding cellular components results in over-expression of legumain, and constitutes a key biomarker for a variety of life-taxing sicknesses like cancer, Alzheimer’s/Parkinson’s and acute kidney injury. To suppress the functions of legumain, it is hypothesized that a water soluble and edible biomolecule, namely, butrin (7, 3’, 4’-trihydroxy flavanone-7, 3’-diglucoside) may have the therapeutic potential owing to its special ability to bind …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 1, 2024 · pp. 26–30 Read article
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A Quasi-experimental Research Endeavor to Evaluatethe Impact of a Structured Instructional Program on Adults' Comprehension of Disaster Awareness and Management in Chosen Villages Situated in Moga,Punjab
Abstract: A quasi-experimental research was conducted to evaluate the efficiency of a structured instructional program on adults' comprehension of disasters and their management. The study involved a sample of 60 adults, divided equally into an experimental group of 30 and a control group of 30. The knowledge score of adults in experimental group regarding disaster and its management among adults was average (54%) and below average (46%) before imparting the structured …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 1, 2023 · pp. 25–31 Read article
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A Quasi-experimental Research Project Designed to Evaluate the Impact of a Structured Educational Program on the Awareness of Cervical Cancer Prevention Among Adolescent Girls Attending Specific Schools in Moga, Punjab
Abstract: A quasi-experimental research study aims to evaluate the efficacy of a structured educational program in enhancing the understanding of cervical cancer prevention among adolescent girls in specific schools located in Moga, Punjab. The knowledge score of adolescent girls in experimental group regarding prevention of cervical cancer was average (20%) and below average (80%), before imparting the structured teaching programme knowledge of adolescent girls were good (70%) and average (30%). The …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 1–9 Read article
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Unveiling the Role of Lead Molecules in CADD: A Systematic Review
Abstract: The word "medicate plan" alludes to the objective creation of modern drugs. Arbitrary screening of engineered compounds, engineered of organically dynamic compounds based on actually happening drugs, amalgamation of basic analogs of actually happening lead particles, and usage of the bioisosteric hypothesis are a few of the strategies that have been utilized. As a result, the most recent drift in medicate plan is to either completely enhance a lead or …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article
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Advancements in Machine Learning: A Comprehensive Review of Algorithms, Applications, and Future Directions
Abstract: Gaining knowledge of Machine learning (ML)-guided format algorithms leverage predictive models to generate novel devices with optimized properties across several domains, which include drug discovery, fabric synthesis, and biomolecular engineering. Selecting an effective format set of policies consists of identifying appropriate hyperparameters, predictive models, and generative mechanisms to maximize format fulfilment. This study introduces an established method for set of policies requirements, ensuring that generated designs meet predefined fulfilment criteria, …
Published in Recent Trends in Programming languages · Vol. 12, Issue 2, 2025 · pp. 17–33 Read article
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Examining Job Satisfaction and its Effect on Employee Productivity of a Textile Industrial Unit
Abstract: Productivity, especially the productivity of human resources, which is one of the necessities of the growth and development of every society and organization; It is not achieved by simply increasing salaries and benefits and amenities. Rather, making people productive depends on creating satisfaction and increasing job satisfaction. The current research is a descriptive-correlation method; The purpose of the research is to investigate the relationship between job satisfaction (Powell-e Specter model) …
Published in International Journal of Behavioral Sciences · Vol. 1, Issue 1, 2024 · pp. 26–38 Read article
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Evaluating the Impact of the Valsalva Maneuver on Pain Relief During Intravenous Cannulation in Patients at Selected Hospitals in Tirupati, Andhra Pradesh
Abstract: Pain can be defined as an unpleasant tactile sensation, arousing sensory experience, and an emotional response that is linked to any type of tissue, cell, or skin damage. Pain is a very common and a primary reason for which people seek health care. Among all the non-pharmacological methods for pain relieving, the Valsalva maneuver is one of the methods which is found effective in reducing the level of pain a …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 Read article
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A New Paradigm in the Intersection of Science and Consciousness through the Microvita Theory
Abstract: Microvita theory, first proposed by philosopher Prabhat Ranjan Sarkar, posits the existence of subtle energy-based entities called "Microvita" that act as the missing link between consciousness and matter. This paper explores Microvita as a novel conceptual framework that bridges the gap between particle physics, consciousness studies, and environmental sustainability. Unlike traditional scientific paradigms, which often exclude the non-material dimensions of reality, Microvita theory asserts that subtle energies and conscious forces …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 16, Issue 2, 2025 · pp. 7–13 Read article
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An Investigation into the Impact of a Structured Teaching Program on the Knowledge of Women’s Rights in India Among Working Women in Selected Government Organizations in North Gujarat
Abstract: A study was conducted to evaluate the impact of a structured teaching program on the knowledge of women’s rights in India among working women in the government sector of North Gujarat. The research used an evaluative approach, specifically a pre-experimental design with a one-group pre- test and post-test. A non-probability purposive sampling method was used to select participants from a government sector in North Gujarat. The sample included 50 women …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 23–27 Read article
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Extraction, Isolation, Characterization of Curcumin-I From Curcuminoids
Abstract: The major goal of this study is to extract, isolate, and characterize curcumin-I, a component of curcuminoids. Turmeric, or Curcuma longa Linn., plays a significant role in Ayurvedic medicine. Turmeric, or Curcuma longa Linn, is the popular name for this plant. An array of chemicals with biological activity may be more easily extracted with the help of this seasoning. Some of the compounds at play include curcuminoids and turmerone, although …
Published in Journal of Polymer & Composites Read article
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A Study to Evaluate the Effectiveness of Planned Teaching Program of Environmental Health Among Community People in Selected Rural Area of Gwalior
Abstract: Context: Environmental health is the subfield of public health that focuses on identifying and altering environmental contributors to illness and injury. The state of the environment in a certain area, especially as it relates to ecological diversity and pollution. The purpose of this research was to evaluate the efficacy of an environmental health education program for the local population. This study follows a quantitative research approach for its methodology. The …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 23–32 Read article
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Evaluating the Efficacy of a Self-instructional Teaching Module on Home Care Management Knowledge for Renal Failure Patients Undergoing Hemodialysis in a Selected Hospital in Ambikapur, Chhattisgarh
Abstract: The kidneys, with their remarkable organization and precision in regulatory functions, exhibit a level of sophistication that can be likened to a divine quality. In a conducted study, a substantial correlation was identified between the pre-test knowledge scores of participants and specific demographic factors, particularly educational qualifications. The chi-square values calculated for educational qualifications were 18.85, and for previous knowledge, it was 6.56. In both instances, the calculated values surpassed …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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Oral Self-examination: An Approach for Early Recognition of Oral Cancer Among Factory Workers: An Experimental Study
Abstract: Background: Cancer is a worldwide concern and ranks among the most dreaded illnesses across the globe. Oral cancers are one common cancer among all cancers. Objectives: To measure the existing knowledge concerning oral self-examination for timely recognition of oral cancer among factory workers and to develop and administer a planned health education programme of oral self-examination for early recognition of oral cancer among factory workers. 40 factory workers were selected …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 22–26 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Comparative Study Between Dashavatara (Incarnation) and Darwinian Theory of Evolution
Abstract: The word Dashavatara derives from Dasha, meaning “Ten”, and Avatara, roughly equivalent to “Incarnation”. Lord Vishnu manifested in various avatars to safeguard the universe and reinstate “peace and dharma” during the four distinct yugas, or cosmic cycles. The Hindu text Dashavatara, which describes ten forms of Lord Vishnu, has a better developed theory of evolution than the hypothesis put out by English scientist Charles Darwin in the 17th century. Objective …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 14, Issue 1, 2024 · pp. 50–58 Read article
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Review on Spirulina ( Green Alage)
Abstract: Spirulina is an edible blue-green algae that is a plant protein source. In recent years, its health benefits have attracted scientific attention, including micro-level examinations of the algae's bioactive components. As proof of concept, investigations conducted in vitro, in vivo, and ex vivo have shown how spirulina works and how it affects immunity. Spirulina has been used as a whole food and as a nutritional supplement for many years. It …
Published in International Journal of Pathogens · Vol. 1, Issue 1, 2024 · pp. 33–37 Read article