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5 articles for “hydroxy propyl cellulose”
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Formulation and Evaluation of Diltiazem Hydrochloride Sustained Release Matrix Tablets
Abstract: Tablets are the most popular and versatile formulations with wide acceptance when compared to other dosage forms due to ease of administration, storage and transport. Diltiazem HCl is a calcium channel blocker widely used for its peripheral and vasodilator properties in the treatment of hypertension and angina. The objective of the present study is to prepare and characterize novel sustained release tablets of freely water soluble drug Diltiazem HCl using …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 2, 2015 · pp. 17–27 Read article
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Formulation Development and Evaluation of Opthalmic Ocusert Containing Timolol Maleate
Abstract: The aim of formulating timololmaleate occusert was to prolong the drug residence time after ocular administration to achieve the controlled release of drug. Timolol maleate is an antiviral agent and it is used in the treatment of viral infections like herpes simplex infections. Ocular inserts were prepared by solvent casting method. Drug reservoir and rate controlling membrane were prepared using different hydrophilic and hydrophobic polymers respectively with polyethylene glycol 400 …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 4, Issue 1, 2017 · pp. 8–12 Read article
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Formulation and Development of Iguratimod Film Coated Tablets 25 mg
Abstract: Iguratamide is chemically called as methanesulfonanilid for the treatment of rheumatoid arthritis. The present invention relates to the micron zing technology for insoluble polycrystal medicine Iguratimod, and the micronized Iguratimod has new crystallization and powder direct compression method for formulating tablets. The orally taken quick release preparation with micronized Iguratimod as active component, high efficiency super disintegrants like cross carmellose sodium, surfactants like sodium lauryl sulphate, diluents like MCC PH …
Published in Trends in Drug Delivery · Vol. 7, Issue 1, 2020 · pp. 25–31 Read article
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Floating In-Situ Gel for Gastric Retention Delivery
Abstract: When taken orally, medications with a limited window of absorption in the gastrointestinal tract (GIT) are typically accessible to the extremities due to the partial release of the active component and the brief residence period at the absorption site. Because they prolong the duration of the drug's presence in the stomach, they are made with high density and have the capacity to swell. Because oral fluids go more quickly through …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 24–32 Read article
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Formulation Development and Evaluation of Floating Tablets of Venlafaxine Hydrochloride
Abstract: The aim of the present study was to formulate and evaluate gastroretentive floating tablets of an antidepressant drug, Venlafaxine HCl. The matrix tablets of Venlafaxine hydrochloride were prepared by employing low viscosity grade hydrophilic polymer HPMC E15LV in combination with any one of the high viscosity grades of HPMC (K4M, K15M, and K100M) as swelling polymers. Sodium bicarbonate was employed as gas generating agent. The tablets were formulated using direct …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 1, 2015 · pp. 7–15 Read article