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9 articles for “formulation optimisation”
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Evaluation of Polysaccharide-Based Membranes for Transdermal Drug Delivery in Chronic Pain Management
Abstract: In order to improve treatment effectiveness and patient compliance, chronic pain management is still a major challenge in modern healthcare, requiring creative medication delivery methods. The potential of polysaccharide-based membranes for transdermal drug delivery is assessed in this work, with particular attention to chitosan, alginate, and hydroxypropyl methylcellulose (HPMC). Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were two characterization techniques used to assess the membranes' physical and chemical …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 28–38 Read article
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Development and Assessment of Levetiracetam Microspheres Utilizing Synthetic and Natural Polymers: A Biomedical Engineering Perspective
Abstract: In the present study, comparative study of Levetiracetam loaded microspheres using Ethyl cellulose as synthetic and Sodium alginate as natural polymers was done. Solvent evaporation and ionic gelation technique has been successfully employed to produce Levetiracetam loaded ethyl cellulose and sodium alginate microspheres with optimal drug encapsulation that sustained the drug release over a period of time. Based on the pre-formulation studies E1 to E4 and S1 to S4 batches …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 1–18 Read article
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Representation-Theoretic Symmetry Reduction and Fuzzy-Grey Optimization of Modular Vibration Systems
Abstract: This paper presents a representation-theoretic framework for symmetry-aware vibration control in modular structural systems. Exploiting cyclic symmetry, the mass, damping, and stiffness operators are block-diagonalised into irreducible representations, reducing the full structural dynamics to a collection of lower-dimensional modal subsystems. This decomposition provides both computational efficiency and a rigorous mathematical description of symmetry-preserving dynamic behaviour. To account for imperfections arising in practical implementations, near-symmetry defects in stiffness and damping are …
Published in Emerging Trends in Symmetry · Vol. 2, Issue 1, 2026 · pp. 22–30 Read article
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Revolutionizing Optical Fibre Field Distribution with Linear Finite Element Method
Abstract: This study investigates the use of the linear Finite Element Method (FEM) for the analysis of the field distribution in optical fibres. Understanding the distribution of electric and magnetic fields is necessary to characterise fibre properties including mode profiles, propagation constants, and dispersion, all of which are essential for optimising fibre performance in a range of applications like sensing and telecommunications. This study emphasises on applying a linear FEM formulation …
Published in Trends in Opto-electro & Optical Communication · Vol. 15, Issue 3, 2025 · pp. 32–42 Read article
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Polymer Composite-Enhanced Anaerobic Digestion of Kitchen Waste for Optimised Biogas Production: Process Design, Parametric Study, and Simulation Analysis
Abstract: There is an urgent need for decentralised sustainable biogas production from organic waste due to the rising amount of food waste in cities. The application of polymer composite material including HDPE tanks, PVC pipes, and FRP secondary containment systems presents a promising option compared to conventional MS digester fabrication in terms of durability, excellent thermal insulation capability, light weight, and easier installation. This study explores the possibility of adopting a …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 803–818 Read article
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A Review of Different Polymer and Plasticizers
Abstract: Plasticizer and polymer are essential components in the pharmaceutical industry, especially when creating both cutting-edge and conventional drug delivery systems. The differences between synthetic, semi-synthetic, and all-natural polymers are examined in this review to highlight their diverse qualities and uses. When designing drug delivery systems to target areas, the choice of polymer is crucial. Because of their repeatability and adaptability, synthetic polymers are widely used in the creation of precision …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 1–7 Read article
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Parametric Investigations of Melt Flow Index for Nylon6-Mica Composite Based Hybrid FDM Filament
Abstract: The development of new hybrid filaments with improved mechanical and thermal properties has been driven by the increasing need for high-performance materials in additive manufacturing. This study explores the parametric investigations of the Melt Flow Index (MFI) for Nylon6-Mica composite-based hybrid Fused Deposition Modeling (FDM) filament. The investigation uses the Taguchi technique to examine how different extrusion temperatures, loads and the percentage of Mica filler affect the MFI, a critical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 165–173 Read article
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Spectral Intuitionistic Fuzzy Hypergraph Operators and Dominance Kernels for Resilient Discrete Network Design
Abstract: A new discrete-mathematical framework is developed for resilient network design on intuitionistic fuzzy hypergraphs, where uncertainty is explicitly represented through membership, non-membership, and hesitation degrees associated with both vertices and hyperedges. These three components are systematically integrated into an effective incidence operator that captures the underlying uncertain relationships within complex hypergraph structures. Based on this operator, both un-normalised and normalized Laplacian matrices are formulated to characterize the spectral properties and …
Published in Recent Trends in Mathematics · Vol. 3, Issue 2, 2026 · pp. 41–48 Read article
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Deep Reinforcement Learning-Based Intelligent Energy Management Strategy for Battery–Supercapacitor Hybrid Energy Storage Systems in Electric Vehicles
Abstract: As the number of EVs increases, smart solutions for energy management are needed that will optimize energy use, prolong battery life and boost vehicle performance. The application of conventional rule based and optimization-based Energy Management Strategies (EMS) for Battery–Supercapacitor Hybrid Energy Storage Systems (HESS) often leads to sub-optimal power management, supercapacitor mismatch and battery degradation when subjected to varying driving conditions. This study aims to design an intelligent energy management …
Published in International Journal of Advanced Control and System Engineering · Vol. 4, Issue 2, 2026 Read article