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13 articles for “cyclodextrins”
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Graph Theoretic Analysis of Cyclodextrin Polymers
Abstract: Topological indicators in chemical graph theory are essential tools in cheminformatics, providing valuable insights into molecular structure and properties to make more accurate predictions about the behavior and efficacy of novel compounds in drug design. The macro molecules are correlated with certain derivatives. The derivatives are growing structures which depends on the cyclic structures. The Cyclodextrin is one of the cyclic structures which depends on the carbon atoms. The polymer …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 997–1006 Read article
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Pluronics®-Cyclodextrin Inclusion Complex for Targeted Drug Delivery System
Abstract: Host–Guest’ inclusion complexes have in Pluronics® and Cyclodextrins (CDs) have an enormous research attraction as drug vehicles. In addition, CDs in Pluronics® solutions has captured much attention for the researchers to develop supramolecular biomaterials by improving the solubility and stability of drugs in aqueous and gel medium by Pluronics®-CDs inclusion complexation. Keywords: Supramolecular, Pluronics®, Cyclodextrins (CDs), Inclusion complex
Published in Trends in Drug Delivery · Vol. 5, Issue 3, 2018 · pp. 1–4 Read article
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Treatment the pediatric rhinitis by CD(Cyclodextrin) garlic suspension
Abstract: Objective: The goal of this study was to identify the effectiveness of vasoconstriction, anti-inflammation and antibiosis of CD garlic powder and to apply this to the treatment of pediatric rhinitis. Materials and Methods: Experimental study objects: Materials: CD garlic powder: we used the CD garlic powder made at Pyongyang Taeun Pharmaceutical Factory. Strain: Escherichia coli O111(ATCC No.25922), Staphylococcus aureus 209-P(ATCC No.25923) purchased from National Microbiological Institute (Pyongyang, DPR Korea). Media: …
Published in Research and Reviews: A Journal of Medicine · Vol. 12, Issue 2, 2022 · pp. 28–33 Read article
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Inclusion of Silver Ions into Modified Cellulosic Fabrics for Durable and Improved Antibacterial Activity
Abstract: Silver ions were added to β-cyclodextrin-grafted organic cotton to create antibacterial fabrics that are more effective and long-lasting. In the presence of sodium hypophosphite, citric acid was used as a cross-linker to graft β-cyclodextrin onto the fabric, cementing the structure for ten minutes at 150°C. The presence of silver ions on the grafted fabric was verified by UV-visible and FTIR spectral studies of β-cyclodextrin, β-cyclodextrin-grafted fabric, ungrafted fabric, silver ions, …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 11, Issue 3, 2024 · pp. 39–52 Read article
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Modified Cellulosic Fabrics with Eugenol Added for Longer-Lasting and Better Antibacterial Activity
Abstract: Eugenol was added to cyclodextrin-grafted organic cotton to create antibacterial textiles with increased efficacy and durability. Grafting of β-cyclodextrin on fabric was done with citric acid as cross linker in the presence of sodium hypophosphite by fixing at 150oC for 10 min. UV-Visible and FTIR spectral studies of β-Cyclodextrin, β-Cyclodextrin-grafted fabric, ungrafted fabric, eugenol and eugenol –loaded fabric confirmed the inclusion of eugenol on grafted fabric. Eugenol was recovered from …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 14, Issue 1, 2023 · pp. 14–28 Read article
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Advances in Solubility Enhancement Strategies for Poorly Water-soluble Drugs: A Comprehensive Review
Abstract: Solubility enhancement holds significant importance in the field of pharmaceutical research as it aims to augment the solubility and bioavailability of drugs that possess low solubility. Poorly soluble drugs pose a considerable challenge in drug development due to their tendency to display inadequate absorption, bioavailability, and therapeutic efficacy. The advancement of solubility enhancement techniques encompasses a wide range of approaches, including physical and chemical methods, as well as innovative technologies …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 01–09 Read article
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Application of Prodrug to Improve Skin Permeability: A Review
Abstract: Administration of drug via skin has some limitations such as skin barrier, solubility of drug and partition coefficient etc. Stratum corneum which is an outer skin layer, acts as a barrier to the skin. Thus, prodrug has some applications to improve skin permeability. Prodrugs are defined as the compounds which are initially inactive but covert into their active form when reacted with several chemicals or enzymes at particular active site …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 8, Issue 1, 2023 · pp. 1–11 Read article
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Design and Development of Sustained Release Tablets using Solid Dispersion of Beclomethasone Dipropionate
Abstract: In present study an attempt was made to enhance the solubility of beclomethasone dipropionate by solid dispersion method followed by formulating sustained release matrix tablet of beclomethasone dipropionate to improve the patient compliance. Beclomethasone dipropionate has poor water solubility and short elimination half-life hence solid dispersion of beclomethasone dipropionate were prepared with β-cyclodextrin and PEG 6000 as carrier by using physical mixture, solvent evaporation and kneading method. The prepared solid …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 2, Issue 3, 2015 · pp. 30–41 Read article
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Water Quality Index Assessment of the Groundwater of Industrial Area and Absorption by Polymer Composites
Abstract: Introduction: Water plays a pivotal role in the existence of human life. Water quality index is an important parameter that helps in improving the quality of drinking and groundwater. Due to anthropogenic activities, the quality of ground and drinking water is decreased. Objective: The main objective of research is to find the water quality index of the groundwater and bore water in selected industrial area of Kakinada and analyse the …
Published in Journal of Polymer & Composites · Vol. 11, Issue 1, 2023 · pp. 36–45 Read article
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Cyanophycin: Production and Its Role as Stabilizer in Nanoparticle Synthesis
Abstract: Cyanophycin also known as cyanophycin granule polypeptide, an exceptional biopolymer produced by diverse cyanobacteria, has attracted considerable attention because of its potential uses in various environmental and biomedical field. In this review paper, we examine the current knowledge about cyanophycin production under different culture mediums and supplements that are consumed by varieties of microorganisms. Cyanobacteria have the capacity to produce cyanophycin, a nitrogen-rich compound generated under stress conditions, such as …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 3, 2024 · pp. 13–26 Read article
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Comparative Study on Oro Dispersible Tablets of Candesartan Cilexetil Formulated with Natural and Synthetic Disintegrants
Abstract: Candesartan cilexetil, a BCS class II drug with low aqueous solubility and poor bioavailability (15%), poses challenges for oral delivery. To address this limitation, the present study focuses on polymer-based inclusion complexation and composite formulation strategies to enhance solubility and dissolution behavior. The drug was incorporated into β-cyclodextrin (β-CD), a cyclic oligosaccharide polymer, by the kneading method in different drug-to-carrier ratios. Among these, the 1:1 molar ratio complex exhibited the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 687–695 Read article
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Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 15–26 Read article
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Oral Capsaicin Ingestion: A Brief Update Dose, Tolerance and Side Effects
Abstract: Capsaicin has attracted increasing scientific attention in recent years relative to its potential pain relief properties, with oral ingestion providing a useful mode of capsaicin delivery. Yet, despite many exciting new findings in this area, there appears to be significant discrepancy across current research so far about an established oral dosage for use in scientific trials. In an attempt improve future research in this area, this commentary provides a short …
Published in Research & Reviews : Journal of Herbal Science · Vol. 5, Issue 2, 2016 · pp. 1–5 Read article