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4 articles for “cryo-electron microscopy”
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Molecular Dynamics and Therapeutic Architectures of Cannabinoid Receptors: A Comprehensive Review
Abstract: Expanding on these foundations, recent structural biology studies using cryo-electron microscopy have provided high-resolution insights into the conformational dynamics of CB₁ and CB₂ receptors. These findings have enabled a more precise understanding of ligand–receptor interactions, particularly how agonists, antagonists, and reverse agonists stabilize distinct receptor states. Such knowledge is critical for rational drug design, allowing researchers to selectively modulate downstream signaling pathways. For instance, CB₁ receptors primarily couple to Gi/o …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 36–40 Read article
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Recent Developments in Structural Genomics: Uncovering Cellular Functions
Abstract: Structural genomics has become a groundbreaking field for understanding cellular functions by revealing the three-dimensional structures of proteins and other biomolecules. This field combines advanced methods like X-ray crystallography, nuclear magnetic resonance spectroscopy, cryo-electron microscopy, and computational modeling to explore the molecular structure and behavior of cellular components. Recent advances have significantly accelerated the pace of structure determination, bolstered by high-throughput methods and artificial intelligence tools like AlphaFold. These developments …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 30–35 Read article
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Description of the tapeworm Tetrabothrius Rudolphi, 1819 (Fam: Tetrabothriidae) in domestic chickens Gallus gallus domsticus
Abstract: The current study aimed to study the morphological characteristics of the tapeworm Tetrabothrius Rudolphi, 1819 by examining it using a light microscope. The present revision was accompanied in Najaf Governorate since January 4/10/2023 to December 1/12/2023. 10 tapeworms of Tetrabothrius sp. were insulated from the innards of 30 resident chickens Gallus gallus domesticus. The morphological features of the tapeworms were considered expending a sunlit optical microscope by tentative the bonce …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 36–41 Read article
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A Review on Effect of Cryogenic Treatment on Wear Resistant Bearing Materials for Automotive Application
Abstract: Cryogenic processing has come as a successful supplementary process to common heat treatment, especially in improving the wear-resistant performance of materials employed in in-vehicle applications. This sub-zero processing is normally performed following quenching and before tempering, during which materials are subjected to extremely low temperatures, typically around -196°C, for prolonged periods of 24 hours. Cryogenic treatment, which involves subjecting materials to extremely low temperatures, has demonstrated promising results in changing …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1–11 Read article