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5 articles for “cisplatin”
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Treatment of Korean Panax Ginseng against Cisplatin-Induced Toxicity in Rats Haematological and Histological Examination of Liver, Spleen and Kidney
Abstract: Vital goal of all anti-cancer therapies are to prevent the incidence of side effects either through more selective therapeutic methodology that target only neoplastic cells or through the use of complementary or alternative medicine. Present study investigated the effects of Panax ginseng (PG) on cisplatin-induced haematological and histopathological (liver, kidney and spleen) changes in rats. Rats were administered with PG (25, 50, 100 mg/kg) before or after an intraperitoneal injection …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 35–39 Read article
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A Review of Medicinal Plants against Drug-Induced Nephrotoxicity
Abstract: Kidney is an excretory organ as it regulates chemical balance and releases waste products from the human body. It is primarily associated with filtration of blood, maintaining level of hormones (mainly vitamin D and erythropoietin) to regulate blood pressure, mineral balance and production of red blood cells. The kidney is more susceptible to drug induced toxicity due to the constant exposure to drug and chemicals present in blood. Over-consumption of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 1, 2025 · pp. 16–26 Read article
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Papillary Thyroidcarcinoma in Rats After Administration of Platinum Compounds Daily
Abstract: Papillary thyroid carcinoma (PTC) predominantly grows in a solid growth pattern with papillary projections, composed of oncocytic cells with “Orphan annie eyes” nuclei. Cisplatin or Cis-Diammine dichloroplatinum (ii) (Cl2H6N2Pt); is a divalent, inorganic and water-soluble first successful platinum containing anticancer drug, used to treat various forms of cancers. The Carboplatin (C6H14N2O4Pt) and Oxaliplatin (C8H14N2O4Pt) are the investigational chemotherapy medicines, belonging to platinum analogue interfere as the Cisplatin with the genetic …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 3, 2015 · pp. 27–31 Read article
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Sequence analysis, DNA Methylation and Molecular therapy of Oral cancer caused by Human Papilloma Virus
Abstract: DNA methylations with oral cancer are been associated with high-risk Human Papillomavirus (HPV) and Epstein-Barr Virus (EBV) onco-proteins interactions may cooperate to increase disease severity. The work focused on human papillomavirus strain 16, a high-risk, sexually transmitted responsible for 95% of all cervical cancers and a large portion of oropharyngeal cancers. The prediction of genes from has shown seven genes from HPV16 strain. Based on gene identification studies, Human papilloma …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 · pp. 1–9 Read article
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Pattern of Care and Pattern of Survival Study in ca Cervix: Implications of a Published Study
Abstract: This article is being written in the context of the recently published multi-institutional study of POSCC for patients of cervical cancer in India. This study involves both private and public funded institutions and has hospitals from most parts of the country. This study is of utmost relevance in current day India, since India alone accounts for one-fourth of the total burden of disease. Stage I cervical cancer has a fairly …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 4, Issue 3, 2015 · pp. 14–18 Read article