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22 articles for “biofilm inhibition”
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Characterization of Antibacterial and Biofilm Inhibition in Tin and Zinc Oxide Nanoparticle-Doped Orthodontic Composites
Abstract: Background: This study investigated the antibacterial effectiveness of orthodontic adhesive enhanced with stannous oxide (SnO₂) nanoparticles against Lactobacillus acidophilus and Streptococcus mutans, in comparison to traditional adhesives without nanoparticle infusion. Methods: A modified orthodontic adhesive was prepared by incorporating 1% w/w of tin dioxide and zinc oxide nanoparticles (SnO₂ + ZnO₂ NPs) into Transbond XT. This nanoparticle-enhanced composite was used to fabricate discs for assessing antibacterial activity against Lactobacillus acidophilus …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 230–239 Read article
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Antibacterial Nanocoatings for Orthodontic Braces and Clear Aligners: Synthesis, Mechanisms, and Translational Potential
Abstract: Orthodontic brackets, archwires and clear aligners create retentive sites that favor biofilm accumulation, leading to white-spot lesions, enamel demineralization and gingival inflammation during treatment. Conventional chemomechanical plaque control has limited effectiveness in this high-risk environment, especially in adolescents with poor compliance. Antibacterial nanocoatings on metallic and polymeric orthodontic components have emerged as a promising strategy to locally suppress cariogenic and periodontopathogenic biofilms while preserving mechanical performance and esthetics. This review …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 2, 2026 · pp. 7–17 Read article
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Chitosan-Based Polymer Coatings for Antimicrobial Catheter Surfaces
Abstract: Catheter-associated infections (CAIs) remain a major clinical challenge. Microbial adhesion and subsequent biofilm formation on catheter surfaces significantly reduce the effectiveness of antimicrobial therapy, resulting in prolonged hospitalization, increased healthcare costs, and higher patient morbidity. Consequently, the development of antimicrobial polymer coatings has emerged as an effective strategy for minimizing catheter-associated infections while improving device performance. Among the various biomaterials investigated, chitosan has attracted considerable attention owing to its intrinsic …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Chemical Composition and Antimicrobial Efficacy of Ferula persica Extracts: A Phytochemical and Bioactivity Assessment in Iraq
Abstract: The research presented in the tables focuses on analyzing the chemical content of extracts from the Ferula persica plant, a wild species in Iraq with significant medical and therapeutic importance dating back to ancient times. This study involved testing some chemical and physical properties of the alcoholic extract of the plant's aerial parts and evaluating its antimicrobial activity, specifically against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). The …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 10–22 Read article
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Heterocyclic Compounds in Thin Film Coatings: A Review on Anticorrosion and Antimicrobial Properties.
Abstract: Heterocyclic compounds have gained significant attention in thin film coatings due to their exceptional chemical versatility and functional properties. These compounds, characterized by the presence of heteroatoms in their ring structures, play a crucial role in enhancing the anticorrosion and antimicrobial performance of protective coatings. This review explores the recent advancements in the application of heterocyclic compounds for corrosion resistance and microbial inhibition, emphasizing their mechanisms of action, effectiveness, and …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 16–21 Read article
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Evaluation of Antibiofilm Potential of Alginate Encapsulated Selenium Nanoparticles
Abstract: Biofilm interfere in antibiotic therapy, undergo gene transformation to become highly virulent, develop quorum sensing and protect bacteria from host immunity. To combat these biofilms the encapsulation method of nanoparticles formation using PEG can be used as they are better alternative to chemical and physical methods. In the present study, the antibiofilm and antioxidant properties of the selenium nanoparticles produced by using probiotics have been evaluated. Transmission electron microscopy (TEM) …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 2, 2018 · pp. 16–21 Read article
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Plant Bioactive Metabolites and Their Role in the Prevention and Control of Dental Diseases and Infections.
Abstract: The oral diseases, including dental caries and periodontitis, affect masses worldwide, and have historically been managed with synthetic antimicrobials that cause deleterious side effects, leading to mounting bacterial resistance. Consequently, contemporary dentistry is rapidly shifting toward phytomedicine using plant bioactive molecules, such as polyphenols, terpenes, anthraquinones (berberin, eugenol, curcumin, catechins, allicin, and azadirachtin. These compounds offer potent antimicrobial, anti-inflammatory, and tissue-regenerative properties that are crucial for preventing and curing dental …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 47–66 Read article
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Nanotechnology in Surgical Drains: Reducing Infections and Promoting Healing Post-Surgery
Abstract: Surgical drains are widely used in postoperative care to evacuate accumulated fluids, minimize dead space, and reduce complications such as hematoma and seroma formation. Despite their clinical importance, conventional drains are frequently associated with retrograde bacterial migration, biofilm formation, and increased risk of surgical site infections (SSIs), which contribute significantly to postoperative morbidity and prolonged hospital stay. Recent advancements in nanotechnology have enabled the development of nano-functionalized surgical drains with …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 2, 2026 · pp. 54–67 Read article
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Inhibition of Quorum Sensing to Mitigate the Risks of Membrane Biofouling in Biological Wastewater Treatment
Abstract: Membrane-based systems play a pivotal role in various applications, providing efficient separation, purification, and filtration processes across diverse industries such as water purification and desalination. However, this system faces major challenge of membrane biofouling impacting the efficiency and sustainability of such systems. Biofouling occurs when various microorganisms like bacteria, fungi, etc. adheres to the surface of membrane and form biofilm which results in reducing membrane permeability and increasing its operational …
Published in Research & Reviews : Journal of Ecology · Vol. 13, Issue 1, 2024 · pp. 18–26 Read article
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Inhibition of Bacterial Communication, Relevance to Periodontics: A Review
Abstract: To survive in hostile environment, bacteria communicate and coordinate their behavior. This cell-to-cell communication and coordination in bacteria or quorum sensing (QS), regulates bacterial growth, metabolism, biofilm formation, virulence factor secretion and various other essential functions in bacterial colonies. Many diseases of human beings, including gingival and periodontal diseases are mediated and regulated by this inter species communication. This high level of interspecies interaction is integral to the development and …
Published in Research and Reviews: A Journal of Dentistry · Vol. 7, Issue 2, 2016 · pp. 18–23 Read article
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Pharmacokinetic Profiling and Molecular Docking of Carvacrol and Structural Analogs: Targeting Quorum Sensing Proteins to Disrupt Biofilm-Mediated Antimicrobial Resistance in Multidrug-Resistant Bacterial Pathogen
Abstract: Antibiotic resistance, particularly in Pseudomonas aeruginosa, has become a major global health threat, exacerbated by the organism's ability to form biofilms and regulate virulence through quorum sensing (QS). The LuxR and LasR receptors are key regulators in this process, influencing both pathogenicity and antibiotic resistance. This study investigates potential QS inhibitors targeting these receptors as a strategy to mitigate antibiotic resistance. The primary objective was to identify novel ligands that …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 43–61 Read article
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Quorum Sensing and Biofilm Dynamics in Pathogens: An Evolving Frontier in Infectious Disease
Abstract: Bacterial and fungal pathogens rarely act as solitary invaders. Instead, they engage in sophisticated chemical communication known as quorum sensing (QS) to coordinate population-wide behaviours and construct structured, multicellular biofilm communities. These biofilms, composed of extracellular polymeric substances, not only facilitate microbial persistence on biotic and abiotic surfaces but also confer remarkable protection against host immune defenses and antimicrobial therapies. QS systems act as central regulators of biofilm dynamics, orchestrating …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 18–23 Read article
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Copper Sulfide Semiconducting Nanoparticles for Antibacterial Applications: Synthesis Strategies, Mechanisms and Performance – A Review
Abstract: Copper sulfide nanoparticles (CuS NPs) have drawn growing attention as a next-generation antibacterial platform, owing to their tunable structural, optical, and catalytic properties. This review consolidates current evidence on CuS NP synthesis, mechanisms, and antibacterial performance, comparing chemical and green synthesis routes alongside the effects of morphology, doping, and surface modification. Mechanistically, CuS NPs act through several overlapping pathways, including reactive oxygen species generation, bacterial membrane disruption, ion release, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 236–253 Read article
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Marine Algae-Derived Bioactive Compounds: Pharmaceutical Applications and Pharmacological Activities
Abstract: Antibacterial strategies that go beyond traditional target-based antibiotics are necessary because antimicrobial resistance (AMR) is a significant and developing threat to the treatment of infectious diseases. Marine algae, which include microalgae and macroalgae (green, brown, and red seaweeds), live in chemically varied environments and produce structurally unique metabolites that can impede the persistence, virulence, and survival of bacteria. This review explores the pharmacological potential of marine algae-derived bioactive compounds against …
Published in International Journal of Marine Life · Vol. 3, Issue 2, 2026 Read article
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Protein Modeling and Drug Docking Studies on Potential Protein Target (E. coli–dosP) and Compound Aldehyde (Sumatriptan) using Bioinformatics Tools
Abstract: The aim of the present in silico studies is to find out the potential protein target in stationary phase-induced biofilm regulator (E. coli–dosP) and deliver the 3D structure and to introduce the best inhibitors of aldehydes (Sumatriptan) using molecular drug docking techniques. The potential chemical compound, Aldehyde (Sumatriptan) was retrieved from NCBI PubChem compound database and converted into the 3D structure using online smiles translator and finally docking studies were …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 5, Issue 3, 2018 · pp. 9–18 Read article
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Impact of Therapeutics on Carbapenem-Resistant Acinetobacter baumannii
Abstract: Acinetobacter baumannii, a formidable pathogen in healthcare settings, poses a significant threat due to its propensity to cause nosocomial infections. This bacterium exhibits several attributes that enable it to evade the human body's natural defenses. A. baumannii's remarkable adaptability is highlighted by its ease in acquiring antibiotic resistance determinants, rendering it challenging to treat. Its ability to thrive in hospital environments underscores the urgent need for stringent infection control practices …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article
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Studies on Waste Water Treatment in Three Phase Semifluidized Bed Bioreactors: Computer Aided Analysis and Software Development
Abstract: Design and performance analysis of three phase semifluidized biofilm reactors for aerobic treatment of industrial effluents have been attempted. Bioconversion processes that follow Monod-type kinetics and those following Haldane-Andrews kinetics (involving substrate inhibition to microbial growth) have been considered as typical cases. The bioreactor has been modelled mathematically by solving performance equations separately for the packed section and for the fluidized section, considering dispersed flow in both of these sections, …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 7, Issue 1, 2016 · pp. 1–21 Read article
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Antibiotic Resistance Studies in Streptococcus mutans Isolated from Dental Plaque Samples
Abstract: Dental plaque is an archetypical biofilm composed of a complex microbial community. It is the etiological agent for major dental diseases such as dental caries and periodontal disease. Streptococcus mutans has been heavily implicated in dental plaque formation. The control of plaque can be achieved by mechanical oral hygiene procedures. However, in many cases, that is not enough to completely get rid of the biofilm. The addition of antiplaque or …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 64–72 Read article
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Marine Fungi – An Expandable Source for Production of Novel Bioactive Metabolites: A Comprehensive Review
Abstract: The marine environment, representing the largest and most extreme biome on Earth, serves as an unparalleled reservoir of biodiversity. Within this vast ecosystem, marine fungi have emerged as a prolific source of structurally diverse and pharmacologically active secondary metabolites. Dwelling in habitats characterized by extreme high salinity, high hydrostatic pressure, and low temperatures, these microorganisms have evolved unique biochemical and metabolic pathways to synthesize novel compounds, including pyrrole-imidazole alkaloids, cyclic …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 30–37 Read article
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In vitro Antibacterial Activity of Dietary Spice Trigonella foenum-graecum and Syzygium aromaticum
Abstract: Multi-drug resistant strains of bacteria are broadly distributed in hospitals and are progressively being isolated from community. The aim of the contemporary study was to govern the potential of spices Trigonella foenum-graecum (Fenugreek) and Syzygium aromaticum (Clove) as antibacterial mediators against drug resistant and virulent strains of gram negative pathogens quarantined from urinary pathway infections. Twelve bacterial isolates from urinary tract infections were studied for their ability to produce virulence …
Published in Research & Reviews : Journal of Herbal Science · Vol. 5, Issue 1, 2016 · pp. 6–11 Read article