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13 articles for “analogous relationship”
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Thermal Post-buckling and Large Amplitude Vibration Analysis of Composite Beams vis-Ã -vis Isotropic Beams
Abstract: Thermal post-buckling and large amplitude free vibration analysis of composite beams is directly investigated based on an analogous relationship derived from the behavior of isotropic beams. The applicability of simple analogous relationship derived for the use of composite beams is demonstrated for various layup schemes of symmetrically laminated beam with wide variety of boundary conditions. Numerical accuracy of the proposed approach show an excellent agreement with available finite element solution …
Published in Journal of Aerospace Engineering & Technology · Vol. 3, Issue 2, 2013 · pp. 17–24 Read article
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A Review on Hybrid Inorganic–Polymer Analog Nanocomposites Incorporating Pozzolanic Wastes and nano-Additives
Abstract: The recent progress of polymer matrix nanocomposites (PMNCs) reveals that the performance of matrix and filler is at the core of matrix–filler interaction, interfacial bonding, and well-controlled distribution of nanoscale reinforcements. Applying these concepts, we consider inorganic particulate systems as hybrid nanocomposites, in which a discontinuous inorganic matrix is effectively reinforced via synergistic co-incorporation of pozzolanic wastes and nano-additives. In the composite system described above, silica-, alumina-rich pozzolanic materials serve …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 131–141 Read article
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2D-QSAR (Quantitative Structure Activity Relationship) Study of Probable Inhibitors for Oral and Cervical Cancers, Generation of Model for Pharmacophore Prediction
Abstract: Twenty-four analogs, conjugates and congeners of curcumin reported as inhibitors against HPV 16 E6 and E7 protein targets have been selected for generating QSAR model. The 46 descriptors were calculated using Schrodinger program version quikprop 9.2. Two alternative methods have been used to generate QSAR models. The first model generation was built on 5 descriptors namely glob, QPlogS, CIQPlogS, IP (eV), human oral absorption which were subjected to multiple linear …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 1–13 Read article
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3D-QSAR Studies on Protein Phosphatase 2A Inhibitors as Anti-cancer Agents
Abstract: The tremendous efforts by researcher indicates that cantharidin, nor cantharidin and their analogues shows anti-cancer activity due to their inhibition of cancer cell lines such as HT29, SW480, MCF-7, A2780, H460, A431, DU145 and L1210. The anti-cancer activities of cantharidin, nor cantharidin and their analogues involve the inhibition of serine/threonine protein phosphatises (PPs) activity. In this study, three-dimensional quantitative structure activity relationship (3D-QSAR) like comparative molecular field analysis (CoMFA), and …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 3, 2018 · pp. 1–19 Read article
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Drug-likeness and 3D-QSAR Analysis of 1,2,3-triazoles as Novel Potent HIV-1 Vif Inhibitors: An approach in the development of Leads in the Treatment of HIV Infection
Abstract: AbstractThe human immunodeficiency virus type 1 (HIV-1) Vif protein is one of various primate lentiviral accessory proteins that act as a virulence factor to advance viral duplication and persistence. 3D quantitative structure-activity relationship (QSAR) modeling of thirty-six (36) newly discovered 1,2,3-triazole analogs as potent novel inhibitors of HIV-1 Vif to predict their biological activity (pIC50), to try to improve/optimize it using some numerical data of HIV-1 Vif inhibitors based on …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 3, 2022 · pp. 23–37 Read article
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Ligand Efficiency in Relation to 3D Physicochemical Characters of Novel HIV-1 Vif Antagonist: An Approach in The Optimization of HIV Drugs
Abstract: AbstractLigand efficiency is a design framework commonly used in drug discovery. Thirty-six (36) newly discovered 1,2,3-triazole analogues as potent new inhibitors of HIV-1 Vif were subjected to quantitative structure-property relationship (QSPR) modeling to predict their ligand efficiencies (LE) in an attempt to improve/optimize it by using some numerical data of HIV-1 Vif inhibitors based on their physical and chemical properties (descriptors). Various 3D physicochemical properties or descriptors were calculated from …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 50–59 Read article
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Correlation Analysis of Gastrocnemius Tightness and Heel Pain Severity: A Study on Plantar Fasciitis
Abstract: Background: Plantar fasciitis, a common source of heel pain, is frequently linked to tightness in the gastrocnemius (GCN) muscle. This study seeks to examine the relationship between GCN tightness and the severity of heel pain in plantar fasciitis patients over time, investigating the potential role of muscle flexibility in alleviating pain. Methods: A prospective cohort study was conducted with 74 patients aged 25–65 diagnosed with P. fasciitis at Santosh Hospital, …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 57–64 Read article
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A Comparative Study Between Rheumatoid Arthritis and Polyarthritis with Respect to Rheumatoid Factor (RF), C-Reactive Protein (CRP), Erythrocyte Sedimentation Rate (ESR) and Visual Analogue Scale (VAS)
Abstract: Arthritis is a form of joint disorder that involves inflammation of one or more joints. Pain, which can vary in severity, is a common symptom in virtually all types of arthritis. The present study is a comparative study between rheumatoid arthritis and polyarthritis with respect to various parameters such as RF, CRP, ESR and VAS. As results, the comparison between these types of arthritis is statistically significant (p < 0.05) …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 4, Issue 1, 2015 · pp. 5–7 Read article
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Comparative Analysis of Processing-Property Relationships in Metal and Polymer Matrix Composites: A Unified Statistical Framework for Hardness Characterization
Abstract: Composite materials, encompassing both metal matrix composites (MMCs) and polymer matrix composites (PMCs), exhibit complex processing-property relationships that fundamentally govern their mechanical performance across diverse applications. This study presents a unified statistical framework for analyzing hardness characteristics in composite systems, using aluminum-tungsten carbide (Al-WC) metal matrix composites as a representative model system while establishing connections to polymer matrix composite behavior. The investigation employed comprehensive processing parameter optimization, microstructural characterization, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 419–430 Read article
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Application of Portfolio Using Fuzzy Logic
Abstract: ABSTRACTA portfolio has to match the portfolio of long-term liabilities with the portfolio of assets. Key instruments in strategic asset liability management (ALM) are the adjustment of investments with respective policies and their interest rate analogous with the scenario of the market. We have given mathematical formulation of the investment problem in terms of stochastic problem (SP) and finally represented it in terms of Fuzzy Inference Engine by providing a …
Published in Journal of Computer Technology & Applications · Vol. 3, Issue 1, 2012 · pp. 16–25 Read article
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions.Methods: A total of twenty-seven …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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A High Frequency and Power Efficient Memristor Emulator and Its Application
Abstract: This study presents a small, energy-efficient memristor emulator made for use at high frequencies. The proposed circuit has a simple design that only includes three n-type MOSFETs and a grounded capacitor. This means that there is no need for active components or DC biasing. This streamlined architecture not only makes things easier, but it also uses very little power, with dynamic and static power measured at 15.82 μW and 65.6 …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 3, Issue 2, 2025 · pp. 45–52 Read article
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article