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7 articles for “acid-peptic disease”
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Review of Ayurvedic Drugs on Acid-peptic Diseases Regarding Its Personalized Management
Abstract: Acid-peptic Disease (~Amlapitta) is an illness wide-spread all around the world. In Ayurveda, Vidahi (which cause burning) and Pitta (dosha responsible for metabolic activities) aggravating diet and stressful –sedentary life-style has been stated as one of the leading cause for acceleration of Amlapitta. Detailed reviewing of drugs given in Ayurvedic texts are done according to specific stage of disease, Amlapitta Dosha predominance, chronicity, associated conditions, dosage, Anupana etc. Screening the …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2024 · pp. 24–38 Read article
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A Comprehensive Review on the Role of Antacids in the Management of Stomach Disorders
Abstract: Antacids are among the most widely used over-the-counter medications for the symptomatic management of acid-related gastrointestinal disorders, including dyspepsia, gastroesophageal reflux disease (GERD), gastritis, and peptic ulcer disease. These agents provide rapid relief by neutralizing gastric hydrochloric acid, thereby increasing intragastric pH and reducing mucosal irritation. In addition to their therapeutic benefits, the long-term and excessive use of antacids may be associated with adverse effects and toxicological concerns, including electrolyte …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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A Systematic Review on Peptic Ulcer Disease and its Pharmacological Treatment
Abstract: A chronic gastrointestinal condition known as Peptic Ulcer Disease (PUD) is typified by the formation of ulcers or mucosal erosions in the proximal duodenum and stomach. In the pathophysiology of PUD, the equilibrium between defensive processes like mucus and bicarbonate secretion, mucosal blood flow, and prostaglandin production, and aggressive factors such stomach acid secretion, pepsin activity, and Helicobacter pylori infection, is upset. Although stress and food have historically been blamed, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 76–84 Read article
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Systematic Review on: Peptic Ulcer and Its Management
Abstract: Peptic ulcer disease (PUD), which affects 5–10% of people worldwide, is still a significant global health concern. Gastric acid and pepsin's corrosive effects cause mucosal injury in the stomach, duodenum, or lower oesophagus. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the primary reasons. This review's goal is to examine PUD's aetiology, risk factors, pathophysiology, clinical symptoms, diagnostic methods, and evidence-based treatment modalities. PubMed, Google Scholar, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 Read article
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Role of Gastric Receptors in Gastrointestinal Disorder
Abstract: The established and potential roles of cholecystokinin1 and cholecystokinin2 receptors in gastrointestinal and metabolic diseases are analyzed, along with findings from human studies involving agonists and antagonists. While there is considerable evidence implicating cholecystokinin1R in various diseases such as pancreatic disorders, motility disorders, tumor growth, satiety regulation, and cholecystokinin-deficient states, its specific role in these conditions remains ambiguous. Conversely, the role of cholecystokinin2R in physiological (e.g., atrophic gastritis) and pathological …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 37–49 Read article
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In Silico Screening and Evaluation of Some Metabolites from Momordica charantia in the Treatment of Peptic Ulcers
Abstract: Peptic ulcers are also called as or duodenal ulcers or gastric ulcers that are open sores generally develop in the lining of the stomach due to food and climatic factors. H. pylori infections are potentially the most dangerous and are linked to several diseases like diabetes, cancer, cardiovascular diseases, etc. In the present study, in silico screening and evaluation of some metabolites from Momordica charantia like Momorcharin, Momordicin, Metformin, Pioglitazone, …
Published in Research and Reviews : Journal of Computational Biology Read article
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Unraveling Ulcerogenesis: A Comprehensive Delve of Enteric & Nonenteric Ulcers
Abstract: Enteric ulcers present a multifaceted landscape encompassing both peptic and non-peptic varieties, demanding a thorough exploration of their manifestations, causes, and pathophysiology. At the forefront of understanding lie pivotal factors such as Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs usage, lifestyle choices, and stress, each wielding significant influence over ulcer development and progression. The intricate interplay of these factors underscores the complexity of enteric ulcer etiology. Helicobacter pylori infection—a prevalent culprit—inflicts …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 25–40 Read article