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300 articles for “K-factor”
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Molecular Docking Analysis of Phytocompounds from Ficus hispida Aagainst Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 Read article
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Molecular Docking Analysis of Phytocompounds from Ficus hispida Against Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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Implementation of Value Management for the Project Success
Abstract: Value management plays an important role in the quality, cost, and functionality of any construction project. The article examines the various applications of value management by examining the methods and techniques in the construction industry. This article examines the various factors involved in the strategies to increase the value of the project and the factors affecting project success. The analysis of the factors was listed according to the priority matrix, …
Published in International Journal of Architectural Design and Planning Read article
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A Better Technique for Controlling Torque to Preload Relationship in the Accurate Assembly of Tiny Threaded Bolt Joints
Abstract: Our industrial, commercial, and even civil worlds are made possible by threaded fasteners or connections, which include all types of bolts. They offer an easy way to connect a limitless number of small parts to form large and practical objects like printing presses, cars, airplanes, and buildings. This paper describes the ways to determine torque to preload relationship in threaded connection and finalizing the optimum torque to be applied. Explains …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 2, 2023 · pp. 30–38 Read article
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A Quasi-experimental Research Endeavor to Evaluatethe Impact of a Structured Instructional Program on Adults' Comprehension of Disaster Awareness and Management in Chosen Villages Situated in Moga,Punjab
Abstract: A quasi-experimental research was conducted to evaluate the efficiency of a structured instructional program on adults' comprehension of disasters and their management. The study involved a sample of 60 adults, divided equally into an experimental group of 30 and a control group of 30. The knowledge score of adults in experimental group regarding disaster and its management among adults was average (54%) and below average (46%) before imparting the structured …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 1, 2023 · pp. 25–31 Read article
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Molecular Docking of Nigella Sativa Phytocompound as Inhibitors of Transcription Factors NF-KB Implicated in Rheumatoid Arthritis
Abstract: Objectives: Nigella sativa, a plant considered around the world as the most treasured nutrient-rich herb for centuries together in different civilizations, is exceptionally known for its high levels of antioxidant properties. Free radical intensification due to oxidative stress plays a key role in the pathogenesis of rheumatoid arthritis by activating the NF-KB protein that regulates the expression of the genes involved in inflammation. Methods: This study involves in-silico approach to …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 42–55 Read article
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To Assessment of the Effectiveness of a Structured Educational Program on Women's Knowledge of Sexually Transmitted Diseases in Rural Areas of Ludhiana, Punjab: A Quasi-experimental Study
Abstract: Background: Maintaining good health is of immeasurable value, as it empowers individuals to lead socially and economically fruitful lives. However, various disorders have the potential to disrupt one's health. Among these, sexually transmitted diseases (STDs) are the most prevalent disorders affecting the reproductive system and other bodily systems, resulting in significant consequences for both families and society. Sexually transmitted diseases (STDs) can be triggered by various microorganisms, including bacteria (like …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 19–26 Read article
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In Silico Molecular Docking of Indigofera tinctoria Phytocompounds to Target EGFR/ERK and FGFR/FGF Pathway Proteins Involved in Prostate Cancer
Abstract: Objective: Prostate cancer being the second major cause of cancer-related deaths in males, affects the small walnut-shaped gland below the bladder called the prostate gland. The epidermal growth factor protein (EGFR), cascade protein (ERK), and fibroblast growth factor proteins (FGFR and FGF) are involved in the different signaling pathways that lead to the formation of different products, that are responsible for the progression of cancer and thus can be considered …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 34–56 Read article
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Frequency of Failed Spinal Anesthesia and Associated Factors in Cesarean Section at Mardan Medical Complex, Mardan, KP, Pakistan
Abstract: Objective: Spinal anesthesia is the preferred choice of anesthesia for parturients having cesarean sections. Despite the high percentage of success in providing acceptable surgical anesthesia, failure of spinal anesthesia has been reported. This study aims to determine the frequency and associated factors related to failed spinal anesthesia during cesarean sections in pregnant women. Methodology: This descriptive cross-sectional study included 149 pregnant women and was conducted at Mardan Medical Complex (MMC) …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 1–9 Read article
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Assess the Knowledge Level Regarding Prevention of Cervical Cancer Among Bachelor of Science Students at Selected Nursing College in Bengaluru
Abstract: Background: Cervical cancer is a major global health concern and one of the primary causes of cancer-related fatalities in women, with particularly high incidence rates in India. Early detection and prevention are crucial, but awareness remains insufficient, especially among future healthcare professionals like nursing students. This study evaluates the knowledge of first-year Bachelor of Science (BSc) nursing students regarding cervical cancer prevention. Materials and Methods: A non-experimental, descriptive research design …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 21–25 Read article
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Understanding Cervical Cancer Screening: An Overview
Abstract: This study aimed to evaluate women's knowledge of cervical cancer screening in relation to specific demographic factors and to create an informational pamphlet on the topic. A total of 190 women aged 20 to 50 participated, selected using convenience sampling. A descriptive quantitative research design was employed, with data gathered through a structured questionnaire assessing socio-demographic factors and knowledge levels. Analysis was conducted using descriptive statistics and SPSS software. Results …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 1–5 Read article
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Assessing Thyroid Disorder Awareness Among Pregnant Women: A Hospital-based Study in Kottayam
Abstract: The current study was carried out at Caritas Hospital to evaluate the knowledge of pregnant women regarding thyroid disorders. The study aimed to assess the level of knowledge about thyroid disorders among pregnant women and to explore the relationship between knowledge levels and selected demographic factors. A total of 194 pregnant women attending the obstetrics and gynecology outpatient department at Caritas Hospital in Kottayam were included using a convenience sampling …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 16–22 Read article
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Post-Antibiotic Gut Microbiota Recovery in the Rumen: Insights into Colonization Patterns, Population Density, and Diversity Dynamics
Abstract: The post-antibiotic recovery of gut microbiota represents a critical area of research in understanding how microbial communities rebalance and re-establish homeostasis following antibiotic-induced disruptions. Antibiotics, while effective against infections, can cause substantial shifts in gut microbiota, leading to dysbiosis – a state of microbial imbalance that impairs gut health and functions. This recovery process involves multiple complex dynamics, including colonization patterns, population density, and the restoration of microbial diversity. The …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–17 Read article
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An Exploratory Investigation into the Understanding of Keratoconjunctivitis Among Staff Nurses at SCPM Hospital in Gonda
Abstract: Background: The primary aim of the present research was to evaluate the comprehension of keratoconjunctivitis among SCPM Hospital staff nurses in Gonda. Methodologically, the study was grounded in the general system theory proposed by Ludwig von Bertalanffy in 1968. To fulfill this aim, a non-experimental descriptive research design was utilized. The study included a sample of 40 SCPM Hospital staff nurses in Gonda who met the predefined inclusion criteria. Purposive …
Published in International Journal of Community Health Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 10–14 Read article
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Nutrient-Mediated Activation of Cellular Signaling Pathways: Mechanistic Insights into Attenuation of Toxin Induced Inflammation in Food Animals
Abstract: Dietary and environmental toxins remain a persistent challenge in food animal production, where subclinical and clinical inflammation compromises health, productivity, and food safety. Toxin induced inflammation is driven by oxidative stress, mitochondrial dysfunction, and dysregulated immune signaling, resulting in impaired metabolic efficiency and increased disease susceptibility. Recent advances in nutritional science have revealed that nutrients act not only as substrates for growth but also as signaling molecules capable of modulating …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 1–12 Read article
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Presenting the Model and Prioritization of Lean Production Success Drivers (Case study: Iran Khodro Company)
Abstract: The purpose of the current research is to present a model and prioritize the drivers of lean production success (case study: Iran Khodro Company). The statistical population and statistical sample of this study consists of 20 experts (managers) of Iran Khodro production department. In this research, first, the most important key success factors of lean production were determined using the validity technique of the content validity ratio, then the interpretative …
Published in International Journal of Sustainability · Vol. 1, Issue 1, 2024 · pp. 30–42 Read article
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A Study on Mental Health, Psychological Support and Life Satisfaction For Tribal Community In Nilgiris-TN
Abstract: This research investigates the mental health challenges, psychological support systems, and overall life satisfaction among tribal communities in the Nilgiris district of Tamil Nadu. These indigenous groups, including the Todas, Kotas, Irulas, and Kurumbas, are undergoing significant social transitions due to modernization, environmental change, and cultural shifts: factors that increasingly influence their mental well-being. The primary objectives of this study are to assess the prevalence of mental health issues such …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 41–45 Read article
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Nanotechnology-Based Cosmeceuticals for Anti-Aging and Skin Regeneration
Abstract: Nanotechnology has transformed the cosmetic industry of the cosmeceuticals by allowing the production of sophisticated delivery systems that improve the stability, penetration, bioavailability, and therapeutic efficacy of active ingredients in cosmetics. The present review identifies the value of nanotechnology-based cosmeceuticals in anti-aging and skin regeneration, with special focus on the recent developments in nanocarrier technologies and their use in dermatology. Many nanocarriers have exhibited great potentials in enhancing delivery of …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 33–45 Read article
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In Silico Exploration of Podophyllum Hexandrum-Derived Phytocompounds as Potential Therapeutics Against Small Cell Lung Cancer (SCLC): A Molecular Docking Approach
Abstract: Small Cell Lung Cancer (SCLC) is a fast-growing and aggressive type of lung cancer that spreads quickly strongly associated with smoking. It is characterized by symptoms, such as persistent cough, breathing difficulties, or hoarseness, though it can sometimes be asymptomatic which makes early detection challenging. The tumor suppressor gene TP53 is critical in regulating the cell cycle and preventing uncontrolled cell division. Mutations in TP53 result in the loss of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 1–11 Read article
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A Study to Assess the Prevalence of Self-medication and Its Associated Factors Among Pregnant Women in Selected Tertiary Care Teaching Hospital at Kuppam, Chittoor District, Andhra Pradesh
Abstract: Self-medication, the practice of using medications without a doctor's prescription, is a growing global public health issue, particularly in resource-limited settings. In pregnancy, self-medication can pose serious risks, including misdiagnosis, incorrect dosages, drug interactions, and prolonged use. This study aimed to assess the prevalence of self-medication, and the factors associated with it among pregnant women at a tertiary care teaching hospital in Kuppam, Chittoor district, Andhra Pradesh. A descriptive cross-sectional …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 41–48 Read article