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14 articles for “IgG”
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Development of Anti IgG Polyclonal Antibody Against Canine IgG and Their Roles in Diagnostic Purposes
Abstract: IgG plays an important part in immunological studies and also in living bodies for providing secondary immune response which triggers as passive immunization against harmful pathogens in dogs. Purpose: The aim of this investigation is to separate, identify, and refine immunoglobulin G from canine serum. Methods: Ammonium sulphate precipitation was used to separate the dog's serum, which was then concentrated over night in a dialysis bag inside of a refrigerator. …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 01–06 Read article
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Study of Platelet Count in Dengue Fever, Function and Their Importance in Hemostasis
Abstract: Dengue infection is a major vector-borne disease. Compatible hematological discovery comprises of vasculopathy, thrombocytopenia, and coagulopathy. The study comprises of 60 patients and all the cases were studied in the Department of Pathology, Kachchhi laboratory, Amreli, Gujarat, India. In this study, out of 60 cases, there were 12 cases of IgG positive and 31 cases of IgM positive. In which seven males had IgG infection and 18 males had IgM …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 1, 2019 · pp. 1–3 Read article
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The Role of Rubella Virus Infection among Women with Spontaneous Abortion in Al-Najaf Governorate
Abstract: Rubella virus could cause a spectrum of birth defects known as Congenital Rubella Syndrome (CRS) if the infection occurs within the first or second trimester of pregnancy. Repeated miscarriage is defined as a condition with two or more consecutive abortions before the 20–25 weeks of gestation. Rubella remains to be a severe public health problem in developing countries. Recurrent miscarriage is a multi-factorial disease, which occurs in approximately 1%–2% of …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 · pp. 1–6 Read article
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TORCH Profile: A Convenient Method for Screening Infection in Pregnancy by ELISA: A Review
Abstract: TORCH is a medical acronym for a set of perinatal infections: toxoplasmosis, other (syphilis), rubella (German measles), cytomegalovirus (CMV), herpes simplex virus (HSV-1, 2). They are a group of viral, bacterial and protozoan infections that gain access to the fetal bloodstream transplacentally via the chorionic villi or hematogenous transmission any time during gestation or occasionally at the time of delivery via maternal-to-fetal transfusion. TORCH infections may result in abortion, still …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 4, Issue 1, 2014 · pp. 16–21 Read article
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Clinical Implications of Serum NT-pro Brain Natriuretic Peptides in Type1 Diabetes with Positive Antiviral Antibodies
Abstract: Subclinical cardiovascular disease is common in diabetes mellitus and is associated with an increased risk of cardiovascular events including heart failure. This study was aimed to assess the association of NT-proBNP as a marker of heart failure and antiviral antibodies in patients with type 1 diabetes mellitus (T1D). One hundred and forty-seven T1D patients (65 male and 82 female) and 24 (11 male and 13 female) non-diabetic control subjects were …
Published in Research and Reviews: A Journal of Medicine · Vol. 3, Issue 1, 2013 · pp. 12–16 Read article
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Diagnosis of Dengue by NS1 Detection: Comparison of Rapid Immunochromatography versus ELISA Kits
Abstract: Dengue is an acute infectious disease of viral etiology. It is probably one of the most important arthropod borne viral disease in terms of human morbidity and mortality. The spectrum of disease ranges from self-limited dengue fever to more severe forms of dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). So, to reduce mortality and morbidity early and accurate diagnosis of dengue is essential. Study assessed comparison of currently …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 2, 2016 · pp. 18–22 Read article
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Isolation and Characterization of “Heavy Chain Antibody” Variable Domain Gene of Indian Desert Camel (Camelus dromedarius, L.)
Abstract: Camelids have “heavy chain antibodies” (HCAbs) of IgG isotype (IgG2 and IgG3 subtypes) and lack light chains and heavy chain constant domain 1 (CH1) in their structure. The molecular biological features of VHH (i.e., antigen binding variable domain of HCAbs) gene isolated from Indian desert camel were examined as a prelude to construct VHHs-phage display library. VHH cDNA was synthesized by reverse transcription-polymerase chain reaction (RT-PCR) from B lymphocyte mRNA, …
Published in Research and Reviews : A Journal of Immunology · Vol. 3, Issue 1, 2013 · pp. 22–31 Read article
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Seroprevalence and Immunity to Dengue Virus Among Women in Punjab: A Public Health Concern
Abstract: Dengue virus (DENV) infection continues to be a public health concern in Punjab, India, where women are at higher risk because of socioeconomic factors. This cross-sectional study sought to assess the DENV seroprevalence, their neutralizing antibody profiles, and the risk factors associated with DENV among a sample of 1,200 women (aged 18–50 years) in Punjab. Serum samples were processed by IgG/IgM ELISA, and plaque reduction neutralization tests (PRNT90) were done …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 1, 2026 · pp. 6–10 Read article
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Molecular and Immunological Study for The Relationship of CMV in Miscarriage in Women with a History of Repeated Abortion in Najaf Governorate
Abstract: The study was conducted in Al-Zahra Hospital for Maternity and Children in Najaf Governorate for the period from 1/8/2024 to 1/1/2025., The stream study directed to establish the occurrence of CMV infectivity in women who experienced of continual miscarriage and perform a analyze of the amount of miscarriage situations arising in the Najaf governorate. The study was divided into two parts. The first part was aiming to determine the frequency …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 1–8 Read article
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Immunologic Characteristics of Apparently Healthy Nigerians Exhibiting Abnormal SPE: A Preliminary Study
Abstract: Abnormal serum protein electrophoresis patterns have been discovered in apparently healthy Africans in Britain and Ghanaians living in Accra, Ghana. Conflicting reasons were suggested for this phenomenon. The aim of present study was to determine the prevalence and characteristics of serum protein electrophoresis (SPE) abnormalities in apparently healthy Nigerians living in Ogbomoso. Three hundred (300) apparently healthy subjects aged 20–30 years were selected for the study. SPE was performed on …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 3, 2015 · pp. 1–6 Read article
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Alopecia Areata: Complex Roots and Potential Cures
Abstract: Autoimmunity is when the healthy organs of an individual’s body are attacked by its own immune system, leading to illness or functional abnormalities. The hair follicles (HFs) are wrongly destroyed by the immune system in a condition known as Alopecia Areata and results in chronic non-cicatricial hair loss discernible by spherical patches. It’s a severely worsening or relapsing malady that can be permanent during severe falling out of hair. In …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 41–54 Read article
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Anaphylaxis: Pathophysiology, Risk Factors, and Clinical Management
Abstract: Anaphylaxis is a syndrome characterized by broncho-constriction, vasodilatation, and hypovolemia, potentially fatal exposure to known or unknown antigens. It can be an immune-mediated (IgE & non-IgE) disease. Immunoglobulin G (IgG), complement related (C3a/C5a), bradykinin, leukotrienes, prostaglandin E2, and ligands of certain G-protein coupled receptors (GPCR) can directly activate mast cells, basophils, eosinophils, neutrophils, endothelial cells and smooth muscles. Serum tryptase level during episodes of anaphylaxis, skin test, and basophil activation …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 · pp. 1–11 Read article
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The Quiet Intruder: An Insidious Presentation of Primary Plasma Cell Leukemia and a Literature Review on Current Treatment Strategies
Abstract: Introduction: Primary plasma cell leukemia (pPCL) is a rare and aggressive plasma cell dyscrasia, defined by ≥5% circulating plasma cells, with poor prognosis and rapid progression. Case Presentation: A 66-year-old African–American female with no prior medical history presented with one week of fatigue, dehydration, and polydipsia. Laboratory evaluation revealed leukocytosis, severe thrombocytopenia, acute kidney injury (creatinine 4.03 mg/dL), and hypercalcemia (13.0 mg/dL) with suppressed PTH. Imaging showed intra-abdominal lymphadenopathy without …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 2, 2026 · pp. 1–5 Read article
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Colostrum: The Nectar for Vitality
Abstract: After parturition, the initial secretion form mammary gland of females is termed as colostrum. Its composition varies from species to species. It is very essential that newborn receives good quality colostrum at an earliest age in required amount so as to have at least 10 mg/ml of IgG level in serum to ensure proper immunity. As the loss in absorptive sites of intestine and digestive enzymes is more with advancing …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 8, Issue 2, 2019 · pp. 19–24 Read article