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3 articles for “Fluoxetine”
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A Review on Effect of Fluoxetine on Human Brain
Abstract: Fluoxetine is a frequently prescribed antidepressant drug that primarily affects the neurotransmitter system of the human brain. Fluoxetine affects the brain by preventing serotonin from being reabsorbed, which raises the concentration of serotonin in the synaptic cleft. In numerous neuronal circuits across the brain, serotonin, a neurotransmitter linked to mood regulation and emotional stability, is essential. By inhibiting the serotonin transporter, fluoxetine increases serotonin transfer and promotes neurotransmission in these …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 13, Issue 2, 2023 · pp. 1–5 Read article
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Effect of Chronic Inescapable Footshock and Antidepressant Treatment on BDNF/TrkB Levels in Rat Hippocampus
Abstract: Depression is a major health problem globally. Chronic stress arising out of life style or social factors may trigger depression, the molecular basis of which has been attributed to alterations of brain chemicals like neurotrophins. Among these neurotrophins, brain-derived neurotrophic factor regulates many physiological functions in the brain, alteration of which has been well associated with the pathogenesis of depression. Stress-induced helplessness in rodents constitutes a well-defined model to investigate …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 2, Issue 2, 2012 · pp. 12–21 Read article
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Depression: As a Risk Factor for Coronary Heart Disease
Abstract: We conducted a review to resolve whether there is relationship between depression and coronary heart disease or not. Depression is a mental health problem which is spread widely and most of physicians are well acquainted with this concept of depression. Diagnosis of depression disorder based on continuity of illness, etiology of illness and number of symptoms-all these discrimination should be reported during inspecting the link between depression and coronary heart …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 12, Issue 2, 2022 · pp. 9–17 Read article