STM Journals Peer-reviewed research from Consortium e-Learning Network

Research and Reviews : A Journal of Biotechnology

A Review on Effect of Fluoxetine on Human Brain

  1. Shishir Tyagi
  2. Akshita Vishnoi
  3. Raxit Tyagi
  4. Surya Prakash D.V

Abstract

Fluoxetine is a frequently prescribed antidepressant drug that primarily affects the neurotransmitter system of the human brain. Fluoxetine affects the brain by preventing serotonin from being reabsorbed, which raises the concentration of serotonin in the synaptic cleft. In numerous neuronal circuits across the brain, serotonin, a neurotransmitter linked to mood regulation and emotional stability, is essential. By inhibiting the serotonin transporter, fluoxetine increases serotonin transfer and promotes neurotransmission in these circuits. When fluoxetine is used, serotonin synaptic availability increases, which affects cognition, emotions, and mood. By modifying the serotonergic pathways, it is thought that fluoxetine can reduce the signs and symptoms of anxiety and depression while also promoting a more stable and balanced mood

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