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39 articles for “Extrusion”
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A Literature Review on Extrusion/Spheronisation-A Pelletization Technology
Abstract: Extrusion-spheronization is a leading pelletization technology, widely favored for its economic and commercial viability. It is a cost-effective method suitable for large-scale production, making it the most efficient approach for oral drug delivery. This process provides multiple benefits, such as improved flow characteristics, lower friability, a narrow particle size range, easier coating, consistent packing, reduced likelihood of dose dumping, and more predictable gastric emptying. Pellets usually measure between 0.5 and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 61–71 Read article
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Analyzing the Sheet Metal Extrusion Process Using Finite Element Analysis
Abstract: A wide range of sheet metal forming techniques has been developed to make it easier to produce intricate 3D objects. However, the knowledge still isn't sufficient. The sheet metal extrusion method was examined in this research as one of the common sheet-bulk metal manufacturing technologies. Consideration of the flow-stress curve's impact across a broad range of plastic strain and ductile damage played a pivotal role in constructing a realistic finite …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 13–25 Read article
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Dimensional Investigation of Material Extrusion Based AM Part
Abstract: Now a day’s additive manufacturing plays a vital role in industrial application. Material Extrusion based 3D printed parts often face inherent limitations in quality, such as geometric inaccuracies, surface roughness, and reduced strength, especially when compared to those made through traditional or more refined manufacturing methods. However, this system provides notable advantages for producing parts from materials like ABS by optimizing critical material extrusion based AM machine process parameters, such …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 442–452 Read article
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Preparation and Characterization of Polyolefins/Inorganic Nano-Filler Nanocomposites via Melt Extrusion Process
Abstract: This work used the melt-mixing method followed by compression molding to create nanocomposites of polyolefins, such as high-density polyethylene and linear low-density polyethylene, packed with both surface-modified and unmodified nano-calcite. The study examined the effects of varying concentrations of nano-calcite, which had been modified using isopropyl tri-(dioctylpyrophosphato) titanate, on the mechanical properties, morphological characteristics, and flow behavior of the resulting nanocomposites. A corotational twin-screw extruder was utilized to manufacture three …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 3, 2024 · pp. 35–43 Read article
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Controlled Release Drug Delivery Using 3D Printing Techniques: A Current Scenario In Personalized Medicine
Abstract: Three-dimensional (3D) printing is particularly influencing the pharmaceutical manufacturing sector in the creation of controlled release drug delivery systems. This technology enables the precise fabrication of personalized medicines with tailored drug release profiles, dosages, and geometries, marking a significant advancement over traditional mass production methods. An array of 3D printing techniques, including extrusion-based, powder-based, and others, can be used to build complex dosage forms that regulate drug release through processes …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 28–43 Read article
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Innovations in Oral Drug Delivery: Challenges and Opportunities
Abstract: The advancement of novel drug manufacturing technologies offers immense opportunities for innovation but brings regulatory complexities that must be addressed to ensure successful implementation. Early and frequent collaboration with the FDA is fundamental for overcoming these challenges. The establishment of the FDA’s Emerging Technology Team has been pivotal in fostering open dialogue, brainstorming, and feedback between regulators and innovators, reducing the likelihood of unexpected setbacks that could jeopardize projects. Mechanisms …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 31–43 Read article
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Development of strontium ferrite/polyamide 12 and neodymium iron boron/polyamide 12 composites using additive manufacturing
Abstract: Polymer matrix composite materials with magnetic properties obtained by the addition of micron-size particles of neodymium iron boron (NdFeB) and strontium ferrite for fused filament fabrication (FFF) are becoming attractive because of their potential applications in the health and automotive industries. Additionally, the design flexibility and low cost of additive manufacturing processes encourage the scientific community to create the materials and understand the properties of the parts obtained with such …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 2, 2025 Read article
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A Review on: Oral Thin Films: A New Approach to Effective and Easy Drug Delivery
Abstract: Oral Thin Film (OTF) is an advance drug delivery system in which drug is incorporated into dissolvable strip and place in oral cavity for rapid absorption. OTF is useful for patient such as pediatric and geriatric who have difficulty swallowing pills. It provides rapid action, precise dosage and improved bioavailability. OTFs consist of fast-dissolving films, extended-release films, and mucoadhesive films for various therapeutic applications. The manufacturing processes of OTFs such …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 22–41 Read article
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Parametric Investigations of Melt Flow Index for Nylon6-Mica Composite Based Hybrid FDM Filament
Abstract: The development of new hybrid filaments with improved mechanical and thermal properties has been driven by the increasing need for high-performance materials in additive manufacturing. This study explores the parametric investigations of the Melt Flow Index (MFI) for Nylon6-Mica composite-based hybrid Fused Deposition Modeling (FDM) filament. The investigation uses the Taguchi technique to examine how different extrusion temperatures, loads and the percentage of Mica filler affect the MFI, a critical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 165–173 Read article
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Development of 3D Printing Filaments from Industrial Waste Plastics
Abstract: The global plastic waste crisis has prompted innovative approaches to sustainable material reuse, particularly in additive manufacturing. Simultaneously, the accumulation of plastic waste presents significant environmental concerns. Recycling plastic into filament supports eco-friendly innovation and brings us closer to a circular economy where materials are reused instead of thrown away. This study investigates the development of 3D printing filaments from industrial waste plastics, including polypropylene (PP), acrylonitrile butadiene styrene (ABS), …
Published in International Journal of Energy and Thermal Applications · Vol. 3, Issue 1, 2025 · pp. 12–17 Read article
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Optimization of Direct Ink Writing Process Parameters for Liquid Silicone Rubber/TiO2 Composite Ink
Abstract: The purpose of this research is to develop and optimize the Liquid Silicone Rubber (LSR)/Titanium Dioxide (TiO₂) composite inks in Direct Ink Writing (DIW)-based 3D printing systems. The primary research objective was to use enhancement of mechanical, rheological, and dielectric characteristics of LSR using TiO₂ reinforcement but still retain extrusion stability and dimensional consistency. TiO₂ content (0, 5, 10, and 15 wt%) and catalyst and glycerol ratios were regulated and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 240–259 Read article
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Deep Learning for Real-Time Monitoring and Defect Detection in Additive Manufactured Polymer Composites
Abstract: Additives Fiber-reinforced polymer composite ADDs have high utility in making lightweight structural components, but due to process-related defects (interlayer delamination and reinforcement stacking) the integrity of consolidation during extrusion-based deposition is frequently compromised. This paper has presented a physics-informed deep learning framework that is applicable to real-time measurements of reinforced thermoplastic composite fabrication. Multimodal sensing was provided with thermal gradient, optical morphology, and acoustics emission signals being used to assess …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 974–999 Read article
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An Innovative AI-Integrated Approach for Identifying the Tensile Robustness of Polymeric Materials
Abstract: Polymeric materials have so many applications and character similar to flexibility, robustness and lightweight nature they are essential to a large variety of industries. Though, it is difficult to establish their tensile robustness appropriately, particularly in a variety of environmental situation. Provide a recommended Artificial Intelligence (AI)-integrated method to decide the issues of rapidly ascertaining the tensile robustness of the polymeric material. Using machine learning (ML), this study, predicted and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 90–97 Read article
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Synthesis of Novel Hybrid Biocomposites and Experimental Investigation of Mechanical Properties
Abstract: As industries increasingly adopt additive manufacturing, the demand for materials that offer better mechanical properties and functionality is on the rise. The purpose of present research work is to develop a novel hybrid biocomposites for 3D printing applications. The acacia bark, waste powder obtained from wet mahanarayan oil consisting of herbs and other bio filler was added in polylactic acid (PLA) for synthesis of hybrid biocomposites filament by twin screw …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 1–12 Read article
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Impact of Layer Height and Infill Line Orientation On 3D Printed Components Produced Via Additive Manufacturing
Abstract: Additive Manufacturing (AM) is an extrusion-based technique used to create objects by extruding semi-molten material through a nozzle of specific dimensions. Materials like acrylonitrile butadiene styrene (ABS), polylactic acid (PLA), polycarbonate (PC), and others are commonly employed in this process to manufacture industrial components. The mechanical properties of engineering component are critical for various industrial applications. This study investigates the impact of additive manufacturing on fabrication, considering different process parameters. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 315–323 Read article
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Influence of Carbonyl Iron Particle Loading on the Dimensional and Rheological Properties of 4D-Printed TPU-Based Magnetorheological Elastomers
Abstract: The advancement of 4D printing technologies has created new opportunities for fabricating smart materials with tunable properties, including magnetorheological elastomers (MREs). This study investigates the fabrication and characterization of thermoplastic polyurethane (TPU)-based MREs with varying carbonyl iron particle (CIP) loadings (10–50 wt.%) using the fused filament fabrication (FFF) method. MRE filaments were produced through a solvent-assisted mixing and extrusion process, ensuring consistent diameters within 1.75 ± 0.10 mm. Test specimens …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 127–138 Read article
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Performance Enhancement of COC-Modified LLDPE Films: Optimization of Stiffness, Tear Resistance, and Barrier through Plasma Surface Modification
Abstract: This study explores the development of high-performance packaging materials by blending commodity Linear Low-Density Polyethylene (LLDPE) with engineering cyclic olefin copolymer (COC) as a performance modifier. To leverage the processability of LLDPE alongside the structural rigidity of COC, blends were prepared at various weight ratios (95/05, 90/10, 85/15, and 80/20) using twin-screw melt extrusion, followed by the production of films and sheets via blown film extrusion and compression molding. The …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 128–143 Read article
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Studies on Mechanical, Optical, Barrier Properties and Characterization of LDPE-PLA Blend Films with Micro Clay
Abstract: Low density poly ethylene (LDPE) and Poly lactic acid (PLA) in the ratio of 70:30 wt% were blended along with ethylene glycidyl meth acrylate (EGMA) as compatibilizer (2.5%), benzophenone as photodegradable additive (1%) and microclay (1,3,5%) as filler. Blending took place in a twin-screw extruder and then the resulting blend was processed into a film using blown film extrusion. Mechanical, optical, barrier and degradative properties of film were tested as …
Published in Journal of Polymer & Composites Read article
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Fast Dissolving Oral Thin Films: A Review
Abstract: Fast-dissolving oral thin films (FDOFs) represent a significant advancement in drug delivery technology, offering advantages over traditional solid dosage forms, especially for patients with swallowing difficulties. FDOFs dissolve rapidly in the mouth, releasing the active ingredient without the need for water or chewing. They have picked up ubiquity due to their comfort, taste veiling capabilities, and progressed persistent compliance. Ideal drugs for FDOFs should possess characteristics such as solubility, stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 24–31 Read article
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Optimizing PLA Filament Production for Enhanced 3D Printing Performance
Abstract: This research explores the optimization of polylactic acid (PLA) filament production to improve its performance in 3D printing applications. PLA is a widely used biodegradable polymer known for its eco-friendliness and ease of processing in additive manufacturing. The study investigates various parameters affecting PLA filament production, including material purity, extrusion temperature, filament diameter consistency, and cooling methods. Furthermore, the research evaluates how these fabrication parameters influence the printability of PLA …
Published in International Journal of Energy and Thermal Applications · Vol. 2, Issue 1, 2024 · pp. 21–29 Read article