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15 articles for “Cardiovascular Events”
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Practical approach for Type 2 Diabetes: Role of DPP4 Inhibitors
Abstract: Dipeptidyl peptidase-4 inhibitors (DPP-4Is) have become essential in managing type 2 diabetes mellitus (T2DM) due to their ability to enhance incretin hormone activity, which promotes insulin secretion and inhibits glucagon release. These agents effectively lower HbA1c levels by 0.5–1.0%, are weight-neutral, and have a low risk of hypoglycemia, making them suitable for a broad patient population, including the elderly. The antidiabetic market in India is vast. Gliptin as group row …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 20–26 Read article
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A Study on the Incidence and Prevalence of Cardiovascular Morbidity and Mortality in Patients Undergoing Maintenance Hemodialysis
Abstract: Cardiovascular Disease (CVD) is a major complication for patients with end-stage renal disease (ESRD) on Hemodialysis (HD), with the mortality rate from CVD being nearly 20 times higher than in the general population. As Chronic Kidney Disease (CKD) advances, patients accumulate both traditional and kidney-specific cardiovascular risk factors, such as hypertension, diabetes, fluid overload, electrolyte imbalances, and uremic toxins. These factors contribute significantly to the increased cardiovascular morbidity and mortality …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 56–66 Read article
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Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in Philadelphia Chromosome-Positive Leukemias: An Overview of Mechanisms, Clinical Implications, and Management Strategies
Abstract: Tyrosine kinase inhibitors have greatly enhanced the outlook for individuals diagnosed with Philadelphia chromosome-positive leukemias, including chronic myeloid leukemia and acute lymphoblastic leukemia. However, these therapeutic agents are associated with Cardiotoxicities and can manifest as left ventricular dysfunction, which may progress to heart failure, along with electrocardiographic abnormalities, dysrhythmias, hypertension, myocardial ischemia, and thromboembolic events. The unclear frequency of drug-induced cardiovascular complications, coupled with uncertainties regarding their reversibility and long-term …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 18–24 Read article
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Review of Atorvastatin As A Potent Drug For Cardio-Vascular Disease(CVD)
Abstract: Cardiovascular disease (CVD), particularly atherosclerosis, remains the leading cause of death worldwide, significantly burdening public health, especially in Western societies. Metabolic syndrome and arrhythmic complications further exacerbate cardiovascular morbidity and mortality. Among restorative specialists, statins particularly atorvastatin have gotten to central in both the essential and auxiliary anticipation of coronary heart infection (CHD) due to their strong lipid-lowering properties and additional pleiotropic impacts. Atorvastatin, a selective HMG-CoA reductase inhibitor, not …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 8–18 Read article
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Assessing the Clinical Efficacy and Safety of Semaglutide: A Comprehensive Study
Abstract: Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), has emerged as a versatile therapeutic agent with significant potential in managing a range of diseases. Extensive research has demonstrated its efficacy in treating obesity, type 1 and type 2 diabetes, and even neurodegenerative disorders like Parkinson’s disease. This comprehensive review examines the principal outcomes derived from clinical trials that incorporate semaglutide alongside other GLP-1 agonists, with particular emphasis on the mechanisms underlying …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 96–104 Read article
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Digital Health Interventions in Cardiovascular Pharmacology: A Review
Abstract: Cardiovascular diseases (CVDs) represent a formidable global health challenge, demanding innovative strategies for timely detection, effective management, and continuous monitoring. This study delves into the transformative potential of digital health interventions (DHIs), such as telemedicine and remote monitoring, in reshaping cardiovascular care paradigms. DHIs offer unparalleled accessibility, convenience, and personalized attention, thereby promising to revolutionize traditional approaches to cardiovascular health management. One of the foremost advantages of DHIs lies in …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 1–5 Read article
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Study of Lipid Profile and Its Correlation with Coronary Angiogram Finding in a Tertiary Care Hospital in an Urban Setting
Abstract: Coronary artery disease (CAD) is a major global health concern caused by the constriction or blockage of the coronary arteries, which can result in serious cardiovascular events. This study looks at the relationship between lipid profiles and the severity of CAD as measured by coronary angiography in patients in a tertiary care hospital. The study focuses on dyslipidemia as a major risk factor for CAD, emphasizing the importance of efficient …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 106–118 Read article
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GLP-1 Receptor Agonists: A Dual Therapeutic Strategy for the Management of Type 2 Diabetes Mellitus and Obesity
Abstract: For the treatment of obesity and type 2 diabetes mellitus (T2DM), glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have become a revolutionary class of pharmaceutical drugs. These drugs were first created as glucose-lowering treatments, but they have now shown other advantages, such as notable weight loss, better cardiovascular results, and general metabolic control. The objective of this narrative review is to assess the pharmacological mechanisms, clinical efficacy, safety profile, and therapeutic …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 69–75 Read article
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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Climate Change & Its Effects on Human Health: A Comprehensive Review
Abstract: Anthropogenic climate change has wide-ranging effects on human health and is a significant worldwide concern. This thorough analysis highlights the connections between environmental, social, and biological elements as it explores the complex implications of climate change on health. Numerous health consequences, such as vector-borne infections, heat-related illnesses, respiratory issues, and mental health issues, can be impacted by shifting precipitation patterns, rising temperatures, and a rise in the frequency of extreme …
Published in International Journal of Climate Conditions · Vol. 1, Issue 1, 2024 · pp. 16–20 Read article
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IoT-based Heart Attack Prediction System Using Machine Learning
Abstract: Heart disease, particularly heart attacks, is one of the leading causes of mortality worldwide. Timely detection and prompt intervention play a vital role in significantly improving the survival rates of individuals at risk of cardiac events. Unfortunately, most traditional healthcare systems are not equipped with mechanisms for continuous, real-time monitoring of patients' cardiovascular health. This limitation makes it extremely difficult for healthcare providers to identify warning signs early enough to …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 12, Issue 2, 2025 · pp. 1–5 Read article
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Integrating Atmospheric Science: Understanding Greenhouse Gases, Aerosols, and Air Quality Dynamics
Abstract: Atmospheric science investigates the Earth’s atmospheric systems to understand their composition, dynamics, and the implications for climate, weather, and air quality. This review explores five primary areas within the field: atmospheric composition, atmospheric modeling, remote sensing, air pollution, and boundary layer dynamics, highlighting critical challenges and advancements. Rising levels of greenhouse gases (GHGs), including carbon dioxide and methane, continue to drive global warming, while feedback mechanisms—like cloud interactions and surface …
Published in International Journal of Atmosphere · Vol. 1, Issue 1, 2024 · pp. 32–35 Read article
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The Heat of Competition: Assessing Climate Vulnerabilities and Adaptive Governance in Endurance, Winter, and Youth Sports
Abstract: Background: Climate change is fundamentally reshaping the environmental parameters of global sport, posing unprecedented risks to athlete health, safety, and performance. As rising temperatures, frequent extreme heat events, and deteriorating air quality become the new normal, athletic environments from community fields to elite international arenas face an existential threat. Purpose: This study provides an interdisciplinary synthesis of the multifaceted impacts of climate change on athletes, integrating evidence from sports medicine, …
Published in International Journal of Climate Conditions · Vol. 2, Issue 2, 2025 · pp. 9–17 Read article
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Role of Artificial Intelligence in Health Care Decision Making: Balancing Innovation and Caution
Abstract: Healthcare is undergoing a transformation powered by artificial intelligence, which improves monitoring, diagnosis, and treatment capabilities. Among Artificial Intelligence (AI's) shortcomings is the dearth of an emotional relationship between individuals and medical personnel. Robotic surgery procedures pose the possibility of malfunctioning machinery and mistaken assumptions. So, the present systematic review focused on exploring the boon and bane of the role of AI in predicting various abnormalities in advance to improve …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 24–35 Read article
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A Systematic Review on Coronary Heart Disease: A Transient Ischemic Stroke
Abstract: Coronary Heart Disease (CHD) and Transient Ischemic Attack (TIA) are significant cardiovascular and cerebrovascular disorders that often share similar risk factors and underlying pathophysiological processes. CHD involves the narrowing or obstruction of the coronary arteries due to atherosclerosis, resulting in diminished blood flow to the heart. A transient ischemic attack (TIA), often called a "mini stroke," occurs when blood flow to the brain is briefly disrupted, usually due to a …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 3, 2025 Read article