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6 articles for “CD4 Counts”
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Stavudine Lamivudine Efavirenz Combination Therapy for Treatment of HIV Infection in Tertiary Care Hospital - A Retrospective Observational Study
Abstract: Highly Active Antiretroviral Therapy has transformed human immunodeficiency virus (HIV) infection into a chronic manageable disease. Compliance is the biggest challenge in low and middle income country like India where social and religious agenda play an important role. Efavirenz based HAART is current standard of care in management of HIV infected patients. The objective of the present study was to know efficacy of combination regimen of stavudine, lamivudine and efavirenz …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 1, 2014 · pp. 17–22 Read article
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Assessment of Adherence to Antiretroviral Therapy Among Art Users in Jimma University Specialized Hospital, Jimma Zone, Oromia Region, South West Ethiopia
Abstract: Background: HIV-associated morbidity and mortality gets substantially reduced with antiretroviral therapy (ART). Antiretroviral treatment efficacy exhibits significant inhibition of viral replication as well as viral load resulting in significant decrease in viral particles to a level where it becomes undetectable in the blood of HIV infected individuals. But, antiretroviral therapy (ART) requires high-level (>95%) adherence and adherence to antiretroviral therapy has been correlated strongly with HIV viral suppression, reduced rates …
Published in Research and Reviews : A Journal of Immunology · Vol. 8, Issue 1, 2018 · pp. 14–21 Read article
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Prevalence of Isospora belli and Cryptosporidium parvum Infections among HIV Sero-positive Patients in Asella Hospital, Central Ethiopia
Abstract: Isospora belli and Cryptosporidium parvum are among the well-defined intracellular, spore-forming, coccidian opportunistic intestinal parasites that cause chronic or acute diarrhea and other life-threatening symptoms in HIV/AIDS patients particularly those with low CD4 count. Therefore, the aim of this study was to determine the prevalence of I. belli and C. parvum among HIV/AIDS sero-positive patients. A hospital based cross-sectional study was conducted at Asella Hospital from January to March, 2013. …
Published in Research and Reviews : A Journal of Immunology · Vol. 4, Issue 1, 2014 · pp. 17–23 Read article
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Evaluation of Chale Neem (Azadirachta Indica) As an Immunomodulator in Elderly Persons: A Single Blind Randomized Placebo Controlled Study
Abstract: Elderly subjects have loss of functionality and dysregulation of immune system. Immunosenescence is associated with deleterious changes, primarily in adaptive immunity and particularly in T cell subset. It includes reduced production of T cells in bone marrow and thymus and diminished function of mature lymphoid tissues. As a result, elderly individuals do not respond to immune challenge and are at increased risk of infection and related complications. Chale Neem (Azadirachta …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 3, 2016 · pp. 48–52 Read article
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An Update on HIV-2 Infection
Abstract: Human immunodeficiency virus type 2 (HIV–2) infection is an important cause of disease in a number of regions of the world. But the knowledge about this infection is sparse. Prevalence data on HIV-2 is heterogeneous. HIV-2 has a lower infectivity than HIV-1 which can be related to the lower RNA levels in this virus. The rate of progression to Acquired Immunodeficiency Syndrome (AIDS) in HIV-2-infected patients is highly variable making …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 2, 2018 · pp. 34–42 Read article
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Cryptosporidium parvum Mediated Diarrhea in Immunocompromised Patients
Abstract: Cryptosporidium parvum is one of the important diarrheal agents, especially in malnourished children and immunocompromised patients. Of the many species, Cryptosporidium parvum and Cryptosporidium hominis are the two major species that cause water borne outbreaks. The geographic difference in the distribution of parasite has been attributed to sources and its mode of transmission. The parasite is able to survive in the environment for long time and is resistant to many …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 3, 2016 · pp. 5–9 Read article