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6 articles for “Anti-filarial”
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Looking Forward to the Promising Anti-filarial Plant Resources and Futuristic Drug Discovery Approaches
Abstract: In tropical and subtropical nations, lymphatic filariasis (LF) is considered a significant public health issue. Adult worms may survive in an infected person for many years, generating microfilariae (mf) and aiding disease transmission via vector mosquitoes. Elephantiasis, river blindness, and tropical pulmonary eosinophilia are among the illnesses caused by filarial worms. The medication of choice for treating filariasis has a slew of negative side effects. Current filariasis control methods aren't …
Published in Research & Reviews : Journal of Botany · Vol. 10, Issue 3, 2021 · pp. 9–23 Read article
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Immunological Biomarkers and Epidemiological Evaluation of Lymphatic Filariasis Elimination Efforts in Osun State, Nigeria
Abstract: Lymphatic filariasis (LF) remains a neglected tropical disease affecting millions globally, despite extensive elimination efforts. While the interruption of transmission is a key goal, the long-term immunological effects on individuals with existing complications like elephantiasis remain poorly understood. This study assessed the current transmission status of LF and the haematological profiles of infected individuals across selected Local Government Areas (LGAs) in Osun State, Nigeria. A total of 7,388 individuals from …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 22–30 Read article
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Review on Biological Properties of Cymbopogon Citratus
Abstract: Lemongrass, Cymbopogon citratus (Poaceae-Gramineae), is an important source of ethnomedicines as well as citral, the primary component of Cymbopogon citratus, which is used in the cosmetic perfumery, and pharmaceutical industries for pathogen control. The word "lemon" comes from the aroma of the plant, which is mostly accountable to the existence of citral, a cyclic monoterpene. Initial research on lemongrass extracts (tea) may have disclosed inconsistent pieces of evidence; however, the …
Published in Research & Reviews : Journal of Botany · Vol. 10, Issue 3, 2021 · pp. 24–27 Read article
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions.Methods: A total of twenty-seven …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Ivermectin: Its Therapeutic Efficacy in the Treatment of COVID-19
Abstract: Over past 35 years the most commonly used anti-helminthic drug is ivermectin. It has showed good impact in treating the parasitic infections. The drug provides an evidence of immune modulatory and anti-inflammatory actions in vitro animal model. Ivermectin belongs to the class of ivermectin and most widely used as an anti-parasitic agent. It is also used in the treatment of internal nematode infections like onchocerciasis, filariasis, and strongloidiasis. For the …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 3, 2021 · pp. 1–5 Read article
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Prevalence and Risk Factors of Neglected Tropical Diseases Among Women and Children in Rural Liberia: A Regional Perspective
Abstract: Neglected Tropical Diseases (NTDs) remain a critical public health challenge in Liberia, disproportionately affecting women and children in rural regions due to systemic inequities in water, sanitation, and healthcare access. This cross-sectional study assessed the prevalence and risk factors of NTDs among 1,000 participants (600 children above 15 years and 400 women aged 15–49) in rural Liberia using stratified and cluster sampling. Laboratory diagnostics, including Kato-Katz stool analysis, urine filtration, …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article