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1978 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Evaluation of the Effect of Zinc Supplementation on Glycemic Control and Lipid Profile in Normoglycemic and Streptozotocin-induced Type-2 Diabetic Rats
Abstract: Diabetes mellitus is a chronic, progressive disease, which is accompanied by multiple complications. Hyperglycemia and dyslipidemia are common complications of diabetes mellitus. The current approaches for treatment of diabetes are mostly dependent on insulin and other oral standard drugs, which have their own put falls. Thus, micronutrients supplementation is gaining momentum as the quest for management of diabetes continues. Certain micronutrients increase insulin synthesis secretion and insulin sensitivity thereby improve …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 2, 2016 · pp. 41–51 Read article
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A Rare Variant of Holoprosencephaly: Ethmocephaly with Inferior Proboscis and Amelia
Abstract: Ethmocephaly is a rare phenotypic variant of holoprosencephaly, characterized by the failure of embryonic prosencephalon to properly divide the orbits of the eye into two cavities with grossly incomplete morphogenesis of fore brain. The severity has a marked variability and ranges from hypotelorism to cyclopia with craniofacial dysmorphism, such as microcephaly with a single central incisor. Reports of this anomaly are few and because of the rarity even among Holoprosencephaly. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 3, 2016 · pp. 1–4 Read article
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Women’s Satisfaction with Care Providers Interaction and Associated Factors among Pregnant Women Attending Antenatal Clinic in Tiyo District, Arsi Zone, Ethiopia, 2016: Institutional Based Cross-Sectional Study
Abstract: Background: Health care provider-client interaction during antenatal care is an effective strategy to improve maternal health care seeking behavior. When clients are informed and involved in decision making, they are more adherent to medical recommendation and carry out more health related behavioral changes. However, the unsatisfactory interaction between health care providers and women pose a significant challenge in the health care service utilization.Objective: This study is aimed to assess women’s …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 6, Issue 1, 2017 · pp. 30–38 Read article
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Thrombocytopenia as an Indicator of Malaria
Abstract: Malaria remains today one of the major health problems in most parts of India with increased morbidity and mortality.Low platelet count is regularly related to malaria and has been describing by numerous workers. Thrombocytopenia is a routine characteristic of severe malaria and happens in both P. falciparum and P. vivax disease regardless of the acuteness of infection. The study was conducted in the population of Nadiyad city, and district Kheda …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 8, Issue 3, 2019 · pp. 1–3 Read article
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Management of Duchenne Muscular Dystrophy by Ayurvedic Principles: A Case Study
Abstract: Duchenne muscular dystrophy is the most common and severe form of childhood muscular dystrophy, with an incidence of 1 case in 3500 male births. It is an X linked recessive disorder due to the absence or alteration of the dystrophin protein, encoded by the DMD gene on chromosome Xp21. Corticosteroids are the only medications that have shown to alter the course of DMD but are associated with their side effects …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 1, 2020 · pp. 1–5 Read article
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Benzimidic Acid Derivatives as Potential Anti-Escherichia coli Agent for Preventing Nosocomial Infections
Abstract: Based on the global fame of benzimidic acid/benzoic acid derivatives in exhibiting antimicrobial activities against a variety of pathogens (particularly nosocomial infections), two novel compounds (S1 and S2) of benzimidic acid scaffold were rationally designed from a hydrazine derivative and fabricated using the conventional synthesis technique. Through sophisticated instruments, the molecules were comprehensively characterized and investigated for antibacterial activity against pathogenic Escherichia coli strain (MTCC 2961). The novel benzimidic compound …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 1, 2020 · pp. 11–15 Read article
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Herbal Immunity Boosters and Dietary Therapies in Covid-19 Prevention
Abstract: The pandemic of Coronavirus, also known as Covid-19 pandemic, is an ongoing global pandemic, caused by extreme coronavirus-2 (SARS-CoV-2). To avoid infection and toughen immunity, foods and herbs may be utilized as nutritional or on the other hand integral treatment to forestall contamination and toughen immunity, as antiviral agents for masks, as disinfectants to control airborne transmission, or as sanitizing agents to clean surfaces. Immunity is the big term right …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 3, 2020 · pp. 39–45 Read article
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Assess the Effectiveness of Music Therapy on Pain Perception and Anxiety Level among Antenatal Mothers in First Stage of Labour at S.G.R.D. Hospital, Vallah, Amritsar: A Quasi-experimental Study
Abstract: The most precious and greatest blessing that God has bestowed upon a woman is motherhood. Women go through a lot of physiological and psychological changes during this period. Therefore, a quasi-experimental study to assess the effectiveness of music therapy on pain perception and anxiety level among primigravida mothers in the first stage of labour at the Sri Guru Ram Das Charitable Hospital, Vallah, Amritsar was carried out. A quantitative quasi- …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 10, Issue 2, 2021 · pp. 49–57 Read article
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A Comparative Study to Evaluate the Effectiveness of Lecture Method of Teaching Versus Video Assisted Method of Teaching on Knowledge Regarding Polycystic Ovarian Disease (PCOD) And Its Management Among Adolescent Girls of Selected Colleges in Nashik City
Abstract: Girls adolescence has long been acknowledged as a unique period that marks the transition from girlhood to womanhood. The onset of menstruation and menarche is the hall mark of female pubertal development. The menstrual cycle is a key sign of a woman's reproductive health and hormonal activity. An evaluative study was conducted among 60 adolescent girls of selected colleges of Nashik. who were divided into two groups (group i with …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 11, Issue 2, 2022 · pp. 1–10 Read article
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The Impact of Knowledge on Food Hygiene Practices Among Food Handlers in a Tertiary Hospital in Nigeria
Abstract: AbstractIn macro-scale cooking, the food is made by many people, thus intensifying the odds contamination of food due to improper handling. Intentional or accidental contamination of food in the course of largescale production can put at risk the health of consumers, and this has a costly consequence on a country. The purpose of this study was to assess knowledge about food safety, attitudes and practices among food handlers in tertiary …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 11, Issue 3, 2022 · pp. 1–7 Read article
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Burden and Practice of Open Defecation in Ethiopia: Narrative Review
Abstract: Open defecation is a universal problem and an estimated 15% to 20% of the global population or more than 1.1 billion people still engage in open defecation. This mini review rapidly focuses on the most important aspects of open defecation, that is, on burden and practice of open defecation in Ethiopia. The search was carried out in PubMed, Medline, Google search, and web sites of relevant governmental and nongovernment agencies …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 1, 2024 · pp. 21–26 Read article
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Lower Extremity Dysfunction in Recreational Footballers: A Cross-sectional Study
Abstract: The purpose of the present study was to evaluate the lower extremity dysfunction in male recreational football players. A cross-sectional survey was carried out on 100 recreational football male players using lower extremity functional scale questionnaire including males and females in the age group 17– 25 years. Football players are most frequently impacted by 37% of them having trouble making abrupt turns while sprinting, 26% having trouble running on uneven …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 21–26 Read article
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Comparison of the Effects of Voriconazole and its Nanogel form on Aspergillus Flavus Isolates in Vitro
Abstract: Aspergillus species are one of the most critical environmental fungi and are considered as a severe factor in causing hospital infections of foreign origin. Objective: Aspergillus flavus is a saprophytic and pathogenic fungus and is found all over the world. In clinical isolates, the voriconazole drug effectively affects more than 95% of Aspergillus isolates. These common drugs have limitations for maximum effect in patients, so nanomedicines are designed and manufactured …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 14–20 Read article
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Mineralization of Phenanthrene by Paenibacillus sp. PRNK-6: Effect of Synthetic Surfactants on its Mineralization
Abstract: Paenibacillus sp. PRNK-6 isolated from a soil contaminated with polycyclic aromatic hydrocarbons (PAHs) was able to utilize 69.48% of phenanthrene (320 mg l-1) in 48 h. The effect of three synthetic surfactants namely, the nonionic surfactant Tween-80, the anionic surfactant sodium dodecyl sulphate (SDS) and the cationic surfactant cetyltrymethyl ammonium bromide (CTAB) on the phenanthrene mineralization by Paenibacillus sp. PRNK-6 was studied. Results showed that the effect of each surfactant …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 3, 2017 · pp. 1–7 Read article
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A Review on Environmental Pollution Mitigation by Fungal Proteases
Abstract: Proteases comprise a vital group of proteolytic enzymes with variety of functions. These enzymes possess the enormous commercial potential and have been used in several industrial processes, including food industry, leather processing, detergent industry and therapeutic applications. As well as they are used as an environmental pollution cleaning agent. Proteases are the replacement of conventional method of silver recovery from the X-ray films. Among the microbial enzymes only proteases constitute …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 3, 2017 · pp. 32–37 Read article
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Comparison of Nested PCR and Real Time PCR of Herpes Simplex Virus Infection in Encephalitis Cases
Abstract: Introduction: Herpes simplex virus (HSV) causes a wide spectrum of clinical manifestations in the central nervous system (CNS). Presently, the development of effective antiviral therapy has resulted in an increased need for the rapid and sensitive diagnosis of HSV infections. Aims: To evaluate the usefulness of real-time PCR for diagnosing HSV encephalitis (HSE), we prospectively compared results of real-time PCR and nested PCR, using clinical samples. Methods and Material: viral …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 34–36 Read article
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Colorimetric Redox Indicator assay for rapid detection of multidrug-resistant Mycobacterium tuberculosis in South Gujarat region
Abstract: Tuberculosis (TB) has affected humans since antiquity. The burden of TB particularly with multi-drug-resistance (MDR) is increasing worldwide and has become a major public health concern. This study aims to perform Colorimetric Redox Indicator (CRI) assay for rapid detection of multidrug-resistant Mycobacterium tuberculosis in South Gujarat region. Total 234 samples were collected from South Gujarat region and were subjected for microscopy examination, culturing on Lowenstein-Jensen (LJ) medium and drug susceptibility …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 65–70 Read article
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Production of High Yield Amylase and Protease by Aspergillus oryzae using Solid-State Fermentation
Abstract: Aspergillus oryzae strains were isolated from different sources and its ability to produce industrial scale amylase and protease using solid-state fermentation was carried in the present study. Different fermentation substrates such as rice bran and wheat bran were evaluated for maximum enzyme yield. Enzyme production was maximum on rice bran and it was achieved with optimized fermentation parameter such as temperature 30°C, pH 4–6, moisture content 60%, inoculum size 0.2 …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 71–78 Read article
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Screening of Cold-Active Lipase from Psychotropic Fungi
Abstract: Lipase is a class of enzymes that catalyze as, hydrolysis of long-chain tri-glycoside and comprise the large significant group of bio-catalysts for biotechnological applications. Currently, the cold-active lipases (CLPS) are the enzyme of choice for pharmacists, organic chemists, biochemical, biophysicists and engineering processes, bio-technologists and micro-biologists as well as biochemists. The production of CLPs is mostly existed from psychrophilic microorganisms. Psychrophiles and psychrotrophs extracellular colds-active enzymes at low temperature (cold) …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 1–5 Read article
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Characterization of Laccase Enzyme from Dye Degrading Bacterial Strains Isolated from Natural Sources
Abstract: The continuous growth in globalization and industrialization has increased the environmental pollution and one such major contaminant is various types of synthetic dyes. Microbial decolorization and degradation of these dyes through secretion of various extracellular enzymes is gaining importance owing to their eco-friendly nature. One such enzyme is laccase, a multicopper oxidase enzyme which has the ability to oxidize both phenolic and non-phenolic compounds through reduction of molecular oxygen to …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 1, 2019 · pp. 65–76 Read article