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1978 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Comparative Analysis of Ovarian Surface Epithelial Lesions with Corresponding Tubal Epithelial Changes with Reference to Ki67 and p53 Immunostains
Abstract: Ovarian surface epithelial cancers have high mortality due to late presentation. The ovarian surface epithelial tumours originate from fallopian tubal epithelium. Hence, ovarian surface epithelial tumours have good correlation with respect to genetic and immunohistological changes of fallopian tubes, especially fimbrial end epithelium. These changes are evident long before significant morphological changes in the ovaries appear. p53 and Ki67 are two important proliferative markers, and useful to evaluate ovarian surface …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 2, 2019 · pp. 6–10 Read article
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Assessment of Routine Child Immunization and Associated Factors Among Children Under Two Years of Age in Jigjiga Karamara Hospital, East Ethiopia
Abstract: Objective: Expanded programme on immunization (EPI) is one of the greatest achievements in medicine and public health, greatly reducing morbidity, mortality and health care costs. Despite various initiatives and campaigns, programme improvement was marginalized in Ethiopia. This study was aimed to assess routine child immunization and associated factors among children less than two years of age in Jigjiga Karamara Hospital, East Ethiopia. Methods: Institutional-based cross-sectional study was conducted on mothers …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 3, 2019 · pp. 25–32 Read article
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Baseline Study about Basic Facts on HIV/AIDS
Abstract: AIDS education is important, especially for young generation; and school is the most important means of reaching out to them. This also applies to the recovering alcoholics and drug users who had been correlated with lifetime tendency towards high risk sexual behaviors. It is easy to think that AIDS is only meant to be worried by drug users, the LGBT community, or people having a lot of sexual partners. This …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 1, 2020 · pp. 30–41 Read article
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Role of Clinical Pharmacist in Evaluation of Women’s Knowledge Status Regarding Vaginal Infections and Its Management - A Hospital Based Study
Abstract: AbstractBackground: Vaginal infections particularly Vaginitis is one of the most frequentgynecological problems in females especially and is one of the most prevalent infections among Reproductive tract infection (RTI)in their reproductive ages and has significant clinical consequences. It is one of the major public health problems among adolescents that cause a considerable proportion of gynecological morbidity and maternal mortality in the developing countries. Aim and Objectives: To assess knowledge status in …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 2, 2020 · pp. 31–38 Read article
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An Insight to Hyponatremia in Cirrhosis: Pathophysiology and Management Approaches
Abstract: Cirrhosis is considered by systemic and splanchnic vasodilation that principals to extreme nonosmotic excretion of vasopressin. Hyponatremia is a mutual electrolyte irregularity in progressive liver disease that outcomes from the diminished capability of the kidney to excrete solute-free water that principals to “dilutional” hyponatremia water retention uneven to the retaining of sodium. Hyponatremia is mutual in cirrhosis. It frequently happens in a progressive phase of the disease and is related …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 3, 2020 · pp. 30–46 Read article
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Development of Zinc Gluconate Vitamin C Effervescent Tablet for Immunity Improvement and Management of Corona Virus Disease (COVID-19)
Abstract: The global pandemic of coronavirus disease- 2019 (COVID-19) continues to pose a threat to people, societies, and economic and healthcare systems. COVID-19s progression and lethality are determine by the host immune system, as is the case with many other diseases. revolutionary idea that has been used to treat other diseases is the control of inflammatory response and cytokine production based on immunonutrition. Some COVID-19 clinical trials are now using zinc, …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 2, 2022 · pp. 4–11 Read article
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Population Genetics and Diversity of Human Adenovirus in Two Tertiary Hospitals in Southern Nigeria
Abstract: The study of dynamic changes in genetic heterogeneity can shed light on the evolution of viruses because it is known that the genetic variety of viral populations within their hosts affects disease progression, treatment outcome, medication resistance, cell tropism, and transmission risk. Our study's primary goal is to identify trends in the genetic makeup and variety of human adenoviruses using samples taken from children who attend two distinct tertiary hospitals …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 3, 2022 · pp. 37–44 Read article
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Knowledge Regarding Birth Control Measure Among Rural and Urban Adolescent Girl: Comparative Descriptive Study
Abstract: Introduction: Adolescent age group of 10–24 year is the beautiful time in which pubertal changes take place. Changes related to high risk sexual behavior and sexual feeling in particular age group need to focus towards the knowledge about contraceptive methods. Objective: To identify and compare the knowledge and attitude of adolescent girls on different birth control devices in rural and urban areas of Ambala, India. Study Design and Setting: The …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 1, 2018 · pp. 10–17 Read article
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ASSESSMENT ON THE KNOWLEDGE, ATTITUDE AND PRACTICE OF SUBSTANCE USE AMONG PREPARATORY STUDENTS OF MEKELLE.
Abstract: Background: Substance abuse has been defined by Asuni et al. as 'excessive or inappropriate use of psycho-active substance by a person; such use being considered or judged to be illegal/immoral by the culture and resulting in harm to the person or society'. Globally, the UNODC estimates that between 155 and 250 million people, or 3.5% to 5.7% of the population aged 15–64 years, had used illicit substances at least once …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 3, 2018 · pp. 6–26 Read article
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Effectiveness of Sign Board on Experiences of Mechanically Ventilated Patients Admitted in Selected Hospitals
Abstract: The objective of the study was to assess and compare the experiences of mechanically ventilated patients with and without the use of sign board. 37 conscious mechanically ventilated patients were selected through purposive sampling technique. In view of nature of the problem and to accomplish the objectives of the study, structured mechanical ventilator experience scale was prepared to assess the experiences of patients (in terms of communication of needs/problems) during …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 3, 2014 · pp. 9–11 Read article
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Seroprevalence of Hepatitis E Virus and Serum Level of Serum Aspartate Transaminase (AST) and Alkaline Phosphatase (ALP) Among Jaundice Patients in Kathmandu Valley, Nepal
Abstract: Hepatitis E is an acute disease caused by hepatitis E virus that usually manifest as acute jaundice. It is a waterborne infection and occurs sporadically or as epidemic outbreaks. Hepatitis E virus (HEV) is a positive-stranded RNA virus with a 7.2 kb genome with three open reading frames In this study we report the seroprevalence of HEV in different categories of jaundice patients along with their elevation of serum bilirubin, …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 3, 2014 · pp. 37–42 Read article
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Case Report on Nevirapine Induced Exfoliative Dermatitis
Abstract: Nevirapine is the first drug of non-nucleoside reverse transcriptase inhibitors (NNRTI) class to treat seropositive patients, administered along with protease inhibitors and/or NRTIs. Nevirapine binds directly to reverse transcriptase (RT) and blocks the RNA-dependent and DNA-dependent polymerase enzyme. Exfoliative dermatitis is wide spread erythema and scaling of skin caused by pre-existing skin disorders, drugs and cancer, unknown causes. HIV infected patients are more prone to Exfoliative Dermatitis. This is a …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 2, 2015 · pp. 7–10 Read article
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Assessment of Hematological Disorders in Patients Using Phenytoin With or Without Nutritional Supplements
Abstract: Phenytoin is the most prescribed drug in controlling the epileptic seizures for prolonged period and this can lead to life-threatening adverse events. This prospective study is aimed to find out the incidence of hematological disorders (HDs) in patients receiving Phenytoin. The authors have screened 100 patients receiving phenytoin for ≥ 6 months, of whom 35 were recruited as per the eligibility criteria and their hematological parameters were noted, 90% of …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 3, 2015 · pp. 1–5 Read article
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Attitude Regarding Mental Illness among Primary Caregivers of Mentally Ill People
Abstract: The present study was undertaken to assess the level of attitude regarding mental illness and find out the association of level of attitude with selected demographic variables among primary care givers of mentally ill people. The hypothesis of the study was that there will be a significant association of level of attitude with the selected demographic variables. Non-experimental approach, descriptive design was used to conduct the study with 30 samples …
Published in Research and Reviews: A Journal of Medicine · Vol. 6, Issue 2, 2016 · pp. 9–11 Read article
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Factors Influencing Institutional Child Birth among Women in Aynalem Kebelle, Mekelle, Tigray, Ethiopia
Abstract: Giving birth is the most critical part of pregnancy intervention for improving maternal and child health in Ethiopia with maternal mortality ratio of 673 per 100,000 live births. The majority of births are delivered at home and the proportion of deliveries assisted by skilled attendant is very low. The present study assessed the factors influencing institutional child birthing among women in Aynalem Kebelle, Mekelle, and Tigray, Ethiopia.A community-based cross-sectional study …
Published in Research and Reviews: A Journal of Medicine · Vol. 6, Issue 2, 2016 · pp. 21–27 Read article
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Knowledge, Attitude and Expressed Practices of Adults Regarding Mental Health
Abstract: The purpose of the study is to assess the knowledge, attitude and expressed practices of adults regarding mental health. A study involving urban and rural areas with 400 adults was carried out. A structured knowledge questionnaire, attitude scale and expressed practice checklist is used to assess the knowledge, attitude and expressed practices of adults regarding mental health residing in urban and rural areas. Results concluded that majority of adults residing …
Published in Research and Reviews: A Journal of Medicine · Vol. 6, Issue 3, 2016 · pp. 32–37 Read article
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Serum Hepcidin Status of Sickle Cell Disease Subjects with Multiple Blood Transfusion in Nigeria
Abstract: Objectives: No effective physiological mechanism for excess iron excretion is known in humans. Conditions such as sickle cell disease (SCD), where red blood cell transfusion is a frequently employed therapy can subsequently result in ready accumulation and circulation of exogenous iron as non-transferrin bound iron in tissues with possible impairment of iron homeostasis in them. Aim: The influence of multiple blood transfusions on the patterns of iron homeostasis in correlation …
Published in Research and Reviews: A Journal of Medicine · Vol. 9, Issue 2, 2019 · pp. 1–9 Read article
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Antibiotic Resistance Patterns of Helicobacter pylori in Africa
Abstract: To eradicate Helicobacter pylori (H. pylori), antibiotic therapy must be adapted to the local resistance patterns. However, the epidemiology of drug resistance pattern of H. pylori is poorly documented in Africa. Therefore, the present review is aimed to review the prevalence of antibiotic resistant H. pylori from previous studies in Africa. A computerized English language literature search of PubMed, MEDLINE and Google Scholar was performed in January 2016. Only 11 …
Published in Research and Reviews: A Journal of Medicine · Vol. 7, Issue 1, 2017 · pp. 4–9 Read article
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Percentage Changes According to Pathological Finding of Gastric Cancer from H. pylori Infections
Abstract: Helicobacter pylori accounts for more than half of the world population in the pathogenesis of gastric cancer. The incidence of gastric cancer among patients with H. pylori infection is 2.7–6 times more than normal. Recently, it has been a worldwide trend to verify the existence of H. pylori using endoscope among all the patients with complaints of digestive abnormality and then introduce anti-cancer therapy with antibacterial therapy from an early …
Published in Research and Reviews: A Journal of Medicine · Vol. 9, Issue 3, 2019 · pp. 5–9 Read article
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Medical Healthcare Applications
Abstract: Medical imaging may be a heatedly contested field wherever winning merchandise maximize healthcare price by providing the simplest pictures within the shortest quantity of your time to assure correct designation and treatment for patients whereas maximizing the potency of workers and facilities. The advancement of medical imaging has resulted in terribly giant knowledge sets and progressively advanced algorithms golf stroke ever-growing demands on process power and gap plenty of opportunities …
Published in Research and Reviews: A Journal of Medicine · Vol. 9, Issue 3, 2019 · pp. 35–38 Read article