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1957 articles for “properly” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Pharmacokinetic Profiling and Molecular Docking of Carvacrol and Structural Analogs: Targeting Quorum Sensing Proteins to Disrupt Biofilm-Mediated Antimicrobial Resistance in Multidrug-Resistant Bacterial Pathogen
Abstract: Antibiotic resistance, particularly in Pseudomonas aeruginosa, has become a major global health threat, exacerbated by the organism's ability to form biofilms and regulate virulence through quorum sensing (QS). The LuxR and LasR receptors are key regulators in this process, influencing both pathogenicity and antibiotic resistance. This study investigates potential QS inhibitors targeting these receptors as a strategy to mitigate antibiotic resistance. The primary objective was to identify novel ligands that …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 43–61 Read article
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Performance Evaluation of Hybrid Polymer Composite Materials for Electromagnetic Interference Shielding in Flexible and Wearable Electronic Devices
Abstract: Wearable electronic devices require novel hybrid polymer composites that offer flexible, lightweight and highly effective EMI shielding characteristics. The development and characterization of flexible polymer composites combining hard magnetic nanoparticles and electrically conductive fillers are explored. The suitability of thermoplastic polyurethane (TPU), polydimethylsiloxane (PDMS) and epoxy resins for use as EMI shielding composite matrices was evaluated in terms of their flexibility, stability and biocompatibility. Hybrid filler systems were developed to …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 630–648 Read article
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In-Silico Docking of Rubia cordifolia Phytocompounds as Potential MMP-2 Inhibitors for Varicose Vein Management
Abstract: Varicose veins are one of the most common disorders, affecting the vein structure and function of lower limbs, yet there has been no absolute cure found yet. One of the underlying causes for worsening of the condition is the proteolytic activity of MMPs which are a group of enzymes that affect the extracellular matrix (ECM) surrounding the affected veins. Phytocompounds of Rubia cordifolia (Manjishta) were docked against the MMP-2 protein …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 31–42 Read article
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Evaluating Delay Impacts: From Root Cause Analysis to Dispute Resolution
Abstract: Construction projects inherently involve complex coordination among multiple stakeholders, interdependent tasks, and unpredictable external challenges, which frequently cause schedule overruns and disputes. Traditional contractual mechanisms—such as extensions of time (EoT), liquidated damages, and force majeure clauses—serve to define responsibilities, allocate risk, and establish formal dispute pathways when delays arise. For example, EoT provisions protect contractors from penalties when delays are beyond their control, provided proper notice and evidence are submitted …
Published in Journal of Structural Engineering and Management · Vol. 12, Issue 3, 2025 · pp. 11–25 Read article
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Formulation and Evaluation of Transdermal Patch to Enhance Treatment of Alopecia
Abstract: The improvement of novel topical sedate conveyance frameworks has picked up noteworthy consideration due to their potential in upgrading the helpful viability and persistent compliance whereas minimizing systemic side impacts. This thinks about centers on the definition and assessment of transdermal patches planned to discharge allicin, the essential naturally dynamic compound determined from garlic (Allium sativum) extricate. Allicin is eminent for its wide range of pharmacological properties, counting antimicrobial, anti-inflammatory, …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 20–33 Read article
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Exploring the Role of MAPK3 in Major Depressive Disorder: Molecular Docking, Dynamics, and Binding Free Energy Analysis of Natural Compounds as Alternatives to Conventional Drugs
Abstract: Major Depressive Disorder (MDD) is a prevalent neuropsychiatric disorder with limited treatment efficacy and significant side effects associated with conventional antidepressants. Recent studies have highlighted the role of mitogen-activated protein kinase 3 (MAPK3) in the mechanisms underlying MDD, positioning it as a potential target for the development of novel therapeutic drugs. In this study, we employed various computational approaches to explore natural compounds as viable alternatives to synthetic antidepressants. Researchers …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 53–68 Read article
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Anti-Microbial Potential of Onion Peel Extracts
Abstract: Onion (Allium cepa L.) is a source of bioactive compounds, particularly flavonoids such as quercetin, and possesses antioxidant and beneficial properties to health. Onion skin, which is normally considered as waste, has more of these compounds compared to the edible portion. This research sought to isolate and analyze the antioxidant and antimicrobial activity of onion skin with ethanol and hexane using Soxhlet and column chromatography techniques. Antioxidant activity was maximum …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 3, 2025 · pp. 1–10 Read article
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Evaluating Chassis Designs for Gesture-Driven Robots: A Study of Iron, Acrylic, and 3D Printed Solutions
Abstract: Gesture-driven robotic systems are becoming increasingly relevant in applications such as assistive technology, industrial automation, and interactive systems. The choice of chassis material plays a crucial role in determining the robot's mechanical strength, weight, and ease of fabrication. This study systematically evaluates three chassis materials—iron, acrylic, and 3D printed polymers—to determine their suitability for gesture-controlled robots. A standardized robotic configuration, including two rear motors, two front dummy axles, an L298N …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 686–692 Read article
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Enhancement of Gas Sensitivity of Composites of Carbon Derived from Rubber Tree and SnO2 to Detect Ethanol Vapor at Room Temperature
Abstract: Films of composites of activated carbon powder prepared from saw dust derived from core of rubber tree (Hevea Brasiliensis) and tin oxide (SnO2) were fabricated using the doctor blade method. Carbon powder was activated using phosphoric acid at 500°C for 45 minutes. The weight ratio carbon/SnO2 varied from 0 to 12% in steps of 2. The structural, optical and morphological properties of films were investigated using XRD patterns, UV-visible spectrums …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 2, 2025 · pp. 31–44 Read article
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Simulation and Experimental Analysis of Heat Treatment for Steel Tie Rods: A Review
Abstract: The study is related to the actual heat treatment and simulation of the physical deformation of the steel tie rod and compares the observations for process optimization. The general methodology is to go for either traditional or induction hardening after getting the chemical composition of the material, followed by tempering, which is a key technique for improving the mechanical properties of materials, strength, hardness, etc., and to release stresses. This …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 1, 2025 · pp. 43–51 Read article
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AI and ML in the Chemical Industry: A Review of Transformative Applications and Future Prospects
Abstract: The chemical industry, a key growth indicator of the global manufacturing ecosystem, is experiencing a digital transformation driven mainly by advancements in Artificial Intelligence (AI) and Machine Learning (ML) in this sector. These technologies are totally revolutionizing current and traditional methodologies by significantly improving process efficiency, reducing costs of manufacturing, accelerating R&D, and improving safety and sustainability standards. Proper utilization of Artificial intelligence (AI) and machine learning (ML) in chemical …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Low-Grade Heat Recovery: Emerging Materials and Systems for Efficient Utilization
Abstract: Low-grade heat (LGH), generally characterized by temperatures below 200°C, constitutes a significant portion of wasted thermal energy in industrial, commercial, and even residential processes. Despite its vast availability, the efficient recovery and utilization of LGH remains underdeveloped due to its inherently low exergy content and the limitations of traditional heat recovery technologies. The creation of cutting-edge materials and creative system-level approaches for LGH recovery has accelerated significantly as companies continue …
Published in International Journal of Energy and Thermal Applications · Vol. 3, Issue 1, 2025 · pp. 24–29 Read article
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Polymer Chemistry and Composite Materials in Biomedical Applications
Abstract: The integration of polymer chemistry and composite materials has revolutionized biomedical applications. Recent advancements in polymer synthesis, functionalization, and nanotechnology have further expanded their applications, leading to significant improvements in biocompatibility, biodegradability, and mechanical performance. These polymeric carriers protect bioactive compounds from enzymatic degradation, enable controlled drug release, and improve therapeutic efficacy. The integration of polymer chemistry with nanotechnology has enabled the development of highly efficient, targeted therapeutic systems that …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 413–419 Read article
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TiO₂ Nanostructured Material-based Gas Sensor for Detecting Oxygen and LPG Gases
Abstract: This Paper investigates the use of TiO2 nanowires and nanotetrapods on glass and silicon substrates for sensing combustible gases such as LPG (Liquid Petroleum Gas) and Oxygen. The growth of Titanium dioxide (TiO2) nanowires/nanorods/nanotetrapods was investigated using both physical and chemical methods. In thermal evaporation method, both with and without vacuum conditions, was employed to synthesize various TiO2 nanostructures. A vacuum coating machine was utilized to create uniform TiO2 thin …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 443–451 Read article
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Enhancing Delamination Resistance in CFRP Composites through surface Functionalization of Woven carbon Fiber by CuO Nanostructures
Abstract: In order to produce a nanostructured interphase that improves the interfacial interaction with an epoxy resin matrix, copper oxide (CuO) nanostructures were hydrothermally formed onto woven carbon fibers (WCF). Hexagonal CuO nanorods were created using a two-step, seed-assisted solvothermal technique on plain woven carbon fiber. This study investigates the effects of surface modification of carbon fibers by the formation of CuO nanostructures using a hydrothermal technique on the mechanical properties …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 589–602 Read article
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Nutraceuticals Unveiled: Exploring the Science, Benefits, and Future of Functional Food
Abstract: The rapidly developing subject of nutraceuticals is critically examined in this review, with a focus on its scientific basis, proven health advantages, and possible future applications in the functional food industry. Key bioactive ingredients that contribute to the therapeutics effectiveness of functional foods, including flavonoids, polyphenols, carotenoids, probiotics, and essential fatty acids, have been identified and characterized as a result of recent developments in nutritional science. Both experimental and clinical …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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Exploring the Mechanical Characteristics of Three Natural Composite Materials (Kenaf, Sisal, and Banana with Almond shell, Glass, and Silicon carbide fillers): A Comparative Evaluation
Abstract: The current global demand for lightweight, long-lasting, and economically efficient materials is of unprecedented magnitude. Industry sectors including aircraft, automotive, construction, and sports are constantly adapting to fulfil these requirements. Natural composites refer to materials obtained from natural sources that utilise two or more separate components to form a material with improved characteristics. In numerous industries, natural composites offer a potential and ecologically sound alternative to synthetic materials by harnessing …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 492–502 Read article
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Building a Modern Land Registration System: Leveraging Node.js and React.js for Efficiency, Security and Scalability
Abstract: Land registration systems are critical for safeguarding property ownership and enabling efficient real estate transactions. However, traditional systems often suffer from inefficiencies, including lengthy processing times, susceptibility to fraud, and limited accessibility. This study proposes a modernized Land Registration System (LRS) leveraging Node.js for backend development and React.js for frontend design to address these challenges. The system integrates real-time data processing, automated document verification, and role-based access control (RBAC) to …
Published in Recent Trends in Programming languages · Vol. 12, Issue 2, 2025 · pp. 1–6 Read article
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Advancements in Polymer Chemistry for Biomedical Applications: A Focus on Injection Guides
Abstract: Polymers have revolutionized biomedical applications, offering versatility, biocompatibility, and cost-effective manufacturing. This paper explores the role of polymer chemistry in the development of an advanced injection guide for precise drug delivery, aiming to enhance both safety and efficiency in clinical settings. Emphasis is placed on polymer selection, structural design, and functional modifications to improve injection procedures. By leveraging biodegradable and biocompatible polymers, the guide minimizes adverse tissue reactions while ensuring …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 129–136 Read article
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Advancements in Polymeric Capillary Materials for Chromatographic Applications
Abstract: Traditionally, glass capillaries have been the material of choice due to their inertness, transparency, and precision in delivering small sample volumes. However, glass capillaries have significant drawbacks, including fragility, limited flexibility, and difficulties in modification for specialized applications. Recent advancements in polymer chemistry have introduced novel polymeric capillary materials that offer several advantages over conventional glass capillaries. Additionally, they exhibit enhanced durability and resistance to a broad range of chemicals, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 137–144 Read article