Search
221 articles for “treatment optimization”
-
Strategies for the Development and Optimization of Orally Disintegrating Tablets (ODTs) to Improve Bioavailability and Patient Compliance
Abstract: Background: Pharmaceutical scientists have developed Orally Disintegrating Tablets (ODTs) to advance patient drug acceptance and biological system availability through simplified medi-cation delivery especially for children and senior citizens and people who cannot swallow pills regularly. The oral disintegrating tablets dissolve in the mouth within thirty seconds or less (USP 701) while needing no additional liquid thus making them suitable for both emergency treatments. Objective: The research examines ODT development strategies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
-
Synthesis and Characterization of Short Fiber Reinforced Biocomposite Materials
Abstract: The fabrication and characterization of a biocomposite reinforced with banana fiber is proposed in this proposal. The substance used for the grid was epoxy. Hand-layup preparation was the last step in the biocomposite's manufacturing. Biocomposites with various fiber and grid compositions were produced. After treating banana strands with NaOH in the composites manufacturing process, a comparative analysis between biocomposites reinforced with treated and untreated filaments was conducted. The antacid treatment …
Published in Journal of Experimental & Applied Mechanics · Vol. 15, Issue 2, 2024 · pp. 42–53 Read article
-
Role of Dermabrasion Assisted Tangential Excision in Paediatric Electrical Burn Wounds
Abstract: Early removal of necrotic tissue in deep electrical burns by tangential excision decreases scarring and promotes wound healing. Dermabrasion, traditionally used in dermatology for facial resurfacing and scar treatment, has shown promising results when applied to burn wound management. In burn care, dermabrasion serves as a form of blunt debridement, effectively removing superficial necrotic tissue without damaging underlying healthy structures. This technique helps reduce local inflammation and lowers the likelihood …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 Read article
-
Revolutionizing Drug Delivery: Recent Advances in Pharmaceutical Dosage Forms
Abstract: Recent advances in pharmaceutical dosage forms revolutionize drug delivery, prioritizing targeted therapy and patient well-being. Enhanced drug carriers address complex medical challenges, from high-grade gliomas to ocular drug delivery, maximizing therapeutic efficacy while minimizing adverse effects. Traditional dosage forms like tablets and capsules undergo meticulous formulation and manufacturing processes, integrating Quality by Design principles for consistent product quality. Liquid formulations encounter stability challenges, necessitating rigorous stability testing and pH monitoring. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 77–89 Read article
-
The Impact of Nanotechnology in Transforming Neuro-oncology - A Comprehensive Review
Abstract: The treatment of central nervous system (CNS) tumours, including aggressive malignancies like glioblastoma, faces significant challenges. The blood–brain barrier (BBB) blocks nearly 98% of small-molecule drugs from achieving therapeutic levels in the brain, and the heterogeneity of these tumours frequently contributes to treatment resistance and poor outcomes. Traditional approaches, including chemotherapy and radiotherapy, are hindered by systemic toxicity and inadequate drug penetration. Nanotechnology provides a promising alternative, as nanoparticles (NPs) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 627–637 Read article
-
Critical Review on Photocatalytic Polymer Nanocomposites for Indoor Air Purification in Hotels
Abstract: The indoor air quality has become a key measure of health, comfort, and customer satisfaction of a hospitality setting. The challenges that continually affect hotels especially because of volatile organic compounds (VOCs), particulate matter, and microbial pollutants that are present in cleaning agents, furnishing, and human activity. In this regard, the photocatalytic polymer nanocomposites are one of the sustainable and efficient means of purifying indoor air. These materials combine photocatalysts …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 527–541 Read article
-
Performance Evaluation of Kevlar-Sisal-S-Glass Hybrid Composites with Ceramic Fillers for Structural Applications
Abstract: This study examines the mechanical properties of hybrid composite laminates reinforced with Kevlar, sisal, and S-glass fibers, and incorporating ceramic fillers—silicon carbide (SiC) and aluminum oxide (Al2O3)—within an epoxy matrix. The hand lay-up method was utilized to produce the laminates, ensuring a uniform fiber stacking sequence and including 10% filler material. Two composite variations were synthesized: one incorporating SiC and the other Al₂O₃, and both underwent tensile, flexural, hardness, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
-
Polymer Chemistry in Dental Applications: Advances and Innovations
Abstract: Polymer chemistry has revolutionized dental materials, offering enhanced mechanical strength, durability, and biocompatibility. The integration of polymer-based materials in dentistry has led to significant advancements in restorative, prosthetic, and preventive treatments. This paper explores the role of polymers in dental applications, focusing on composite resins, denture bases, impression materials, and adhesive systems. The development and alteration of polymers have led to the creation of advanced materials with enhanced wear resistance, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 16–22 Read article
-
A Computational Study to Elucidate the Phytochemicals as An Antagonist Against Pruritis in Psoriasis
Abstract: Objective: Psoriasis is a chronic, non-contagious, auto-immune skin disorder that causes inflammation, pain, and itching in the affected areas. The etiology of this condition is not entirely understood, and while there are treatments available to manage the symptoms, there is currently no cure. The Transient receptor potential cation channel, subfamily Vanillin, member 3 (TRPV3), present in keratinocytes, allegedly had a part in the development of psoriasis-related pain and itching. Specifically, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 49–61 Read article
-
“DEVELOPMENT AND CHARACTERIZATION OF PHYTOSOMES FOR THE TREATMENT OF ANTI-CANCER ACTIVITY BY USING THE Spirulina (Arthospira Plantesis) EXTRACT”
Abstract: This study aims to investigate and evaluate spirulina's anticancer properties.The current research is centred on obtaining a Spirulina-containing drug. The goal is to design and create Phytosomes, characterizing them based on relevant and crucial parameters. The process of solvent evaporation was utilized in the creation of Phytosomes. Various parameters such as zeta potential, particle size, infra-red spectral analysis, % drug content, encapsulation efficiency, and % drug release (% DR) were …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 10–22 Read article
-
A Study on Smart Healthcare Innovations
Abstract: The desire for effective, patient-centred solutions and the rapid growth of technology are driving forces in the healthcare industry. The term "smart healthcare innovation" refers to a broad category of approaches, tools, and procedures that are intended to improve patient outcomes, optimize resource use, and enhance overall healthcare delivery. These innovations integrate cutting-edge technologies such as artificial intelligence (AI), the Internet of Things (IoT), wearable devices, big data analytics, and …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 2, 2025 · pp. 63–68 Read article
-
Role of Fluid Engineering in Biomedical and Healthcare Systems: A Comprehensive Review
Abstract: Fluid engineering — the study and application of fluid behavior, transport, and interaction — has become a cornerstone of modern biomedical and healthcare systems. This review synthesizes the multifaceted roles fluid engineering plays across diagnostics, therapeutics, biomedical devices, and physiological modeling. Micro-fluidics enables precise manipulation of microliter and nanoliter volumes, facilitating rapid point-of-care diagnostics, high-throughput screening, and the fabrication of uniform nano particles for targeted drug delivery. In cardiovascular medicine, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–5 Read article
-
Computational Biomodeling: Transforming Drug Design with Advanced Simulations
Abstract: Computational biomodeling has emerged as a transformative approach in the field of drug discovery, significantly enhancing the efficiency and precision of identifying and optimizing potential drug candidates. This article explores the various computational techniques utilized in drug design, including molecular docking, molecular dynamics (MD) simulations, free energy calculations, and virtual screening, and examines how these methods collectively contribute to the drug development process. The integration of these advanced simulations allows …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 24–29 Read article
-
Advances in Biological Systems Modeling for Predicting Drug Effects in Chronic Disease
Abstract: Biological systems modeling has emerged as a promising tool for understanding and predicting the effects of drugs in the treatment of chronic diseases. Chronic diseases, such as diabetes, cardiovascular diseases, and neurodegenerative disorders pose significant challenges to traditional drug development due to their complex, multifactorial nature. Systems biology approaches, which integrate computational modeling with experimental data, provide a holistic view of disease mechanisms and treatment responses. This review explores recent …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 17–22 Read article
-
Identification of Promising Lead Compounds from Capsicum annuum Targeting BACE-1 for Alzheimer’s Disease Therapy: A Molecular Docking Study
Abstract: Background: Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions of people worldwide. Beta-secretase 1 (BACE-1) is an important therapeutic target for AD treatment. Capsicum annuum (CA) is a commonly consumed plant with potential neuroprotective properties. In this study, we aimed to identify potential lead compounds from CA that can target BACE-1 for AD therapy using molecular docking. Methods: A library of 15 compounds from CA was obtained from PubChem, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 40–49 Read article
-
Effect of Vermicompost, Compost and Inorganic Fertilizer on Production of Onion at Southern Ethiopia, Wolaita Zone Humbo District
Abstract: Combined application of fertilizers (organic and inorganic) could able to optimize production and productivity of onion. This experiment was conducted in Humbo district southern Ethiopia during 2019- 2021 under irrigation to evaluate the effect of organic and inorganic fertilizer on bulb yield and general production of onion. Experiment was laid out in randomized complete block design with three replication and consisted of seven treatments: T1: control, T2: NPSB(82.2N, 31.4P, 13.4S, …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 1, 2024 · pp. 31–39 Read article
-
Detection and Classification of Diabetic Retinopathy Using Deep Learning Techniques
Abstract: This project delves into the evaluation of three prominent deep learning architectures Basic CNN, ResNet, and DenseNet for their efficacy in detecting diabetic retinopathy from retinal images. Utilizing a diverse dataset, the study employs standard deep learning frameworks to train and validate each model. The focus extends to exploring the potential benefits of transfer learning on a limited dataset. Evaluation metrics like specificity, sensitivity, and accuracy are employed for a …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 64–69 Read article
-
Graphene-Polymer Nanocomposites for Drug Delivery Applications
Abstract: Graphene-polymer nanocomposites (GPNCs) have gained significant attention in drug delivery due to their exceptional physicochemical properties, including high surface area, mechanical strength, tunable functionality, and biocompatibility. These nanocomposites integrate graphene derivatives, such as graphene oxide (GO) and reduced graphene oxide (rGO), with biocompatible polymers to enhance drug loading efficiency, stability, and controlled release. Various natural (chitosan, alginate) and synthetic (PLGA, PEG, PCL) polymers are used to functionalize graphene, enabling targeted …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 362–374 Read article
-
Water Chestnut Stem-Derived Biochar Supported AgNPs/AC-CTS-PVA Composite Gel for Wastewater Treatment and Potent Antibacterial Performance
Abstract: In the present study, green and efficient Ag-NPs functionalized activated carbon/chitosan-polyvinyl alcohol (AgNPs/AC-CTS-PVA) composite gel was successfully synthesized using water chestnut stem-derived biochar for wastewater treatment and antibacterial applications. The composite was characterized by FTIR, XRD, SEM-EDX, and TGA analyses, confirming the successful incorporation of crystalline Ag nanoparticles within the polymeric matrix and improved thermal stability. The material was tested regarding the removal of the dye of methylene blue (MB) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1129–1144 Read article
-
A MediStream Application: Integrated Application for Patient Data and Medical Oversight
Abstract: Maratha Vidya Prasarak Samaj (MVPS) has periodic health check-ups for the students and teachers, however, traditional paper-based records systems are prone to inefficiencies, data loss and administrative overhead. To resolve this issue, a Student Health Record System that is digital in nature is proposed which ensures up-to-the-minute security and management of health information. The system is built with JavaScript, XML, Fire base and offers role-based access for administrators, doctors, interns, …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 2, 2025 · pp. 1–6 Read article