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321 articles for “system biology”
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Quantitative Structure-activity Relationship in Computer-aided Drug Design: A Review
Abstract: Quantitative Structure-Activity Relationship stands at the forefront of Computer-Aided Drug Design, providing a systematic framework for understanding the relationship between the chemical structure of molecules and their biological activity. The present review delves into the multifaceted realm of quantitative structure-activity relationship methodologies within the landscape of drug discovery. Through an exploration of diverse quantitative structure-activity relationship models, molecular descriptors, validation techniques, and recent advancements, the present article aims to elucidate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 55–63 Read article
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Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 15–26 Read article
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Catalytic Trends of OsO4 for the Taurine-Bromamine-T Redox System: Kinetic and Mechanistic Chemistry of Catalyzed and Uncatalyzed Reactions
Abstract: Taurine (2-ethane aminosulfonic acid) facilitates as a building block for protein synthesis, also possessing various other vital biological functions. Literature survey revealed that there was no report available on the oxidation of taurine with any oxidants from its kinetic, mechanistic and catalytic aspects. A detailed comparative mechanistic study of its Os(VIII) catalyzed and uncatalyzed oxidation kinetics by bromamine-T (BAT) in NaOH medium at 313 K revealed the rate law to …
Published in Journal of Catalyst & Catalysis · Vol. 4, Issue 3, 2017 · pp. 5–19 Read article
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Using Artificial Intelligence for The Design of Polymeric Drug Delivery Systems
Abstract: AI is cost effective and time efficient process. Artificial intelligence is a method which uses high speed calculation, the improvement regarding algorithm along with collection about biological and chemical features in pharmaceutical exploration and development .Present day because continuous progress towards machine learning (ML),Artificial intelligence an effective statistics analysing technology might have been broadly utilized in drug design .In pharmaceutical exploration and research employ of AI in target identification, compound …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1018–1027 Read article
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From Differential Equations to Data Science: A Survey on Analytical Methods in Contemporary Problems
Abstract: The integration of differential equations and data science methods represents a dynamic and evolving approach to solving contemporary challenges across a wide range of disciplines, including engineering, physics, biology, economics, and finance. Differential equations have long served as fundamental tools for modeling continuous systems and processes, offering powerful insights into the behavior of natural and man-made phenomena. For example, they describe how heat diffuses through materials, how populations grow in …
Published in Recent Trends in Mathematics · Vol. 2, Issue 2, 2025 · pp. 1–6 Read article
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Review on Azo-Compounds and Their Applications
Abstract: Azo-colored compounds that form the basic structure of many synthesized compounds in many fieldsof chemistry, especially coordination chemistry, as they contain a group (-N=N-). These dyes arewidely used as colorants, as they contribute to nearly 50% of artificial colors. Also in manyapplications such as ink-jet printing, optical imaging, and biomedical diagnostics , azo dye containsone or more D-π-A systems that can produce various colors by changing the electron donation (D) …
Published in Journal of Catalyst & Catalysis · Vol. 8, Issue 2, 2021 · pp. 8–16 Read article
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Role of Tabiat (Quwwat-e-Muddabbira Badan) in The Light of Unani System of Medicine
Abstract: Tabiat is the ordinary power which when exists in a body pledges movements and rest in its obligatorily. Tabiat is fundamentally a power which is a well-prepared system which keeps the body temperament and internal environment. Therapeutic herbs have been used practically in all cultures for enhancement of the immune system. Unani medicines rely on tabyat mudabbira-i-badan which is the complete strength, which accomplishes all the biological tasks of the …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 11, Issue 1, 2022 · pp. 23–26 Read article
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Understanding Kameela's Importance In The Unani System Of Tibb: A Detailed Perspective
Abstract: Kameela or Kamala, a renowned Unani medicine, has been utilized by Unani physicians for centuries to effectively address Amraze Jildiya, commonly known as skin diseases. Its medicinal properties have been extensively documented in classical Unani texts. These perennial shrubs or small trees are widely distributed in tropical and subtropical regions, typically found at altitudes below 1,000 m. The pharmacological activities of Kameela encompass a broad spectrum, owing to its diverse …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 10, Issue 3, 2023 · pp. 16–22 Read article
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A New Paradigm in the Intersection of Science and Consciousness through the Microvita Theory
Abstract: Microvita theory, first proposed by philosopher Prabhat Ranjan Sarkar, posits the existence of subtle energy-based entities called "Microvita" that act as the missing link between consciousness and matter. This paper explores Microvita as a novel conceptual framework that bridges the gap between particle physics, consciousness studies, and environmental sustainability. Unlike traditional scientific paradigms, which often exclude the non-material dimensions of reality, Microvita theory asserts that subtle energies and conscious forces …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 16, Issue 2, 2025 · pp. 7–13 Read article
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Cardiovascular Modeling with Computational and Mathematical Methods
Abstract: The cardiovascular system, a complex network responsible for delivering life-sustaining oxygen and nutrients throughout the body, is a prime target for advanced understanding and improved therapies. Due to the inherent difficulties in directly observing internal physiological processes and the complexities of interactions within the system, computational and mathematical modeling have emerged as powerful tools in cardiovascular research. This article explores the significance of these methods in unveiling the heart's secrets …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 11–21 Read article
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Activation Energy in Photochemical and Thermally Driven Reactions: Mechanistic Insights, Kinetic Modelling and Photocatalytic Applications
Abstract: Chemical reactions constitute fundamental processes in which reactants are transformed into products through the breaking and formation of chemical bonds. In photochemical systems, these transformations are initiated or influenced by the absorption of light, making energy transfer mechanisms particularly significant. A key parameter governing reaction kinetics is activation energy, defined as the minimum energy required for reactant molecules to undergo a successful transformation. This article focuses on the role of …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 21–26 Read article
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Genetic Algorithm: an Optimization Tool for Real World Problems
Abstract: AbstractThe main goal of this research work is to give the lesson on genetic algorithm with the help of evaluation concept of our environment. Genetic algorithm is a type of optimization algorithm, means it is used to find the optimal solution to a given computational problem that maximizes or minimizes a function. Genetic algorithms represent a branch of the field of study called evolutionary computation, in which they imitate the …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 9, Issue 3, 2019 · pp. 17–21 Read article
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The Effects of HIV/AIDS Worldwide
Abstract: The Human Immunodeficiency Virus (HIV), which targets immune system conductors (CD4 cells), has infected millions throughout the world. HIV lowers the body's defences by infecting certain bodily fluids (blood, sperm, vaginal fluids, and breast milk) through unprotected sex, contaminated needles, or mother-to-child transmission. Early flu-like symptoms may go unrecognised, but if not treated, HIV advances to AIDS, which is characterised by severe immune system impairment. However, advances in antiretroviral therapy …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 26–31 Read article
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A Thorough Examination of the Chemical Engineering Process: Fundamentals, Design, and Application
Abstract: This article gives a full picture of the chemical engineering process, focusing on the basic ideas, methods, and tools that make up the profession. It looks at how chemical, physical, and biological processes change raw materials into useful goods, with a focus on how design, optimization, and control work together in industrial systems. Some of the main topics talked about are process design, thermodynamics, reaction engineering, transport phenomena, and sustainability. …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 3, 2025 · pp. 14–25 Read article
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Biodegradable Polymers Properties and Applications
Abstract: Polymers that can degrade into biologically compatible components under physiologic conditions present a far more attractive alternative for the preparation of drug delivery systems. The use of biodegradable polymers precludes the need for retrieval at the conclusion of the dosing regimen, thereby avoiding the potential complications associated with the use of non-degradable systems. A wide variety of approaches are continuously being pursued in the quest for improved biodegradable drug delivery …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 57–72 Read article
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Review On: Liquid Crystal Cream for Topical Drug Delivery
Abstract: A Liquid crystal creams represent a novel approach in skincare formulations, leveraging the unique properties of liquid crystal technology to improve skin hydration and barrier function. An overview of current developments in liquid crystal cream formulations is given in this article, with an emphasis on the benefits they offer for skincare and their composition and structure. Liquid crystal creams mimic the lipid bilayers of the skin, offering enhanced compatibility and …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 1–8 Read article
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Platelets A Tiny Cell Fragments
Abstract: Platelets are disc-shaped, anucleate cells that are approximately 2-3 μm in diameter. Their primary function is to control hemostasis, or blood clotting, but they also play important roles in angiogenesis (the formation of new blood vessels) and innate immunity (the body's first line of defence against infection). With a diameter of just 2-3 microns, platelets are tiny, disc-shaped cells that lack a nucleus. While their main responsibility is to ensure …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 2, 2024 · pp. 22–28 Read article
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How Microfluidics Are Used in Modern Science: Lab-on-A-Chip
Abstract: Microfluidics has changed modern research by making lab-on-a-chip (LOC) technologies that combine multiple lab functions into small, portable devices. These little platforms make it easier to correctly handle small amounts of fluid, which saves time, money, reagents, and automation. This article talks about microfluidics and how it helps LOC technology go forward in all areas of science. We look at important uses of biomedical diagnostics, drug development, environmental monitoring, and …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 2, 2025 · pp. 35–48 Read article
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Harnessing Biomass for Sustainable Insect Farming and Biotechnology: Ecological Roles, Industrial Applications, and Future Opportunities
Abstract: Biomass, derived from biological materials, such as plant residues, animal waste, and agricultural by-products, plays a pivotal role in ecological systems, including those involving insects. Insects interact with biomass at multiple levels, serving as decomposers, pollinators, and converters of organic matter into valuable resources. The integration of biomass into insect ecology and farming has garnered significant attention for its potential in sustainable agriculture, waste management, and biotechnology. This review highlights …
Published in International Journal of Insects · Vol. 2, Issue 1, 2025 · pp. 17–21 Read article
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The Importance of DNA Profiling Today
Abstract: DNA profiling has changed a lot of sectors, from health and criminal justice to ancestry research and animal conservation. It is one of the most important scientific instruments of our time. This technique makes it possible to identify people, analyse family relationships, and learn more about biology by looking at unique genetic markers in a person's DNA. DNA profiling has changed the way forensic science works by making it easier …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article