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1911 articles for “potentials” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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A Comprehensive Review: Medicinal Plants with Potential Antidiabetic Activity
Abstract: AbstractMedicinal plants really play an important role in the treatment of various health problems because of their better acceptance and being safe from undesirable side effects. Diabetes mellitusis is an interesting area of herbal research at present. More than 400 medicinal plants are used to treat diabetes mellitus all over the world. A number of animal studies to test the claimed activity have demonstrated the hypoglycemic property of many of …
Published in Research & Reviews : Journal of Herbal Science · Vol. 4, Issue 1, 2015 · pp. 29–57 Read article
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Metal Tolerance Potential of A. fumigatus and Comparative Analysis of Biosorption through Control and Trained Biomass
Abstract: Heavy metal pollution in water because of the discharge of industrial effluent imposes serious environmental concerns. Copper is one of such pollutants which is are considered as toxic, non-biodegradable and persistent in nature. Removal of heavy metals through conventional treatment strategies can cause many technical problems. Filamentous fungi have the ability to accumulate significant amount of heavy metals from their environment. Therefore, the potential of resistant fungal biomass as biosorptive …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 2, 2019 · pp. 71–82 Read article
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Isolation, Characterization and Molecular Identification of Potential Probiotic Bacterium, Bacillus amyloliquefaciens CS4 from gut of Snakehead Fish, Channa striata (Bloch, 1793)
Abstract: The present study was to isolate and characterize the potential probiotic bacterium from the gutof healthy fish, Channa striata. Totally, 37 bacteria were isolated from the gut region, in whichonly 25 isolates that showed catalase negative were selected. Among the selected isolates, CS4exhibited maximum inhibitory activity against fish (Aeromonas hydrophila, Vibrio harveyi,Vibrio parahaemolyticus) and human (Serratia marcescens) pathogenic bacteria. Theisolate CS4 exhibited potential tolerance to 0.5% bile salts at 24 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 2, 2019 · pp. 1–10 Read article
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Screening of Phytochemicals and Antibacterial Potential of Dicranopteris linearis (Burm.f.) Underw.
Abstract: The present study deals with screening of phytochemical and antibacterial potential of terrestrial fern Dicranopteris linearis (Burm.f.) Underw. collected from Marthandam region of Kanyakumari district of Tamil Nadu, India. The fresh plant material was collected and shade dried for a week and powdered. The powdered material was subjected to gradient extraction with Soxhlet apparatus with two different solvents (acetone and chloroform) and screened for its phytochemical and antibacterial potential. Phytochemical …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 10, Issue 3, 2020 · pp. 1–5 Read article
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Optimization of Dry Basella rubra Leaf Powder in Nachos Preparation and Studying its Antioxidant Potential
Abstract: Basellaceae family (Malabar spinach) is a perennial vine native to tropical Asia. There are two main species of Malabar spinach; Basella alba, which has green stem and thick fleshy leaves and Basella rubra which has red stem. The objective of the study was to investigate the effect of addition of dry Basella rubra leaf powder. Nachos that contained 5 gm% of dry Basella rubra leaf powder had highest overall-acceptability score …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 2, 2019 · pp. 56–62 Read article
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Nondairy desserts: Potential ingredients for the development of innovative formulations
Abstract: With a growing demand for lactose-free foods, the food industry faces a challenge in identifying new food ingredients to replace equivalent chemical constituents of milk, achieve similar rheological properties, and preserve texture stability and sensory properties in milk-free food preparations. This study aimed to systematize data on potential innovative ingredients for the production of nondairy desserts, with a focus on different types of texturizing agents. Cactus mucilages, cereal and legume …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 11, Issue 3, 2022 · pp. 1–9 Read article
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Chemical Potential of Water from Monte Carlo Simulation: The Fundamentals
Abstract: AbstractMonte Carlo simulation was conducted using the Towhee software to calculate the chemical potential of water. The implementation is made simple and provides a clear demonstration of the concept of Monte Carlo simulation. This paper is targeted to new researchers interested in molecular modelling and can be used as a guide for beginners in the art of molecular modelling, specifically Monte Carlo simulation. The purpose of carrying out the calculation …
Published in Research & Reviews : Journal of Physics · Vol. 5, Issue 3, 2016 · pp. 16–27 Read article
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Potential Source of Mesenchymal Stem Cell (MSCs) in Veterinary Medicine
Abstract: Stem cells serve a vital function in veterinary care in a variety of ways. Several stem cell treatments for animal patients are now being developed, and some, such as the treatment of horse tendinopathies using mesenchymal stem cells (MSCs), have already successfully hit the market. Furthermore, animal models are routinely employed to explore the qualities and potential of stem cells for future uses in human health. Furthermore, bovine ES cells …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 11, Issue 1, 2022 · pp. 1–3 Read article
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Bacterial DNA Gyrase (Topoisomerase) Inhibitory Potentials of Heterocyclic Natural Products: Investigations through Induced-Fit Molecular Docking Approach
Abstract: The study exclusively focuses on the exploration towards the hidden potential of heterocyclic natural products against bacterial DNA gyrase (topoisomerase) through induced-fit docking (IFD) by utilizing the Glide module of Maestro 9.1 software. The study will open new doors for the antibacterial drug discovery by the inhibition of imperative biological target. Keywords: antibacterial, DNA gyrase, heterocyclic compound, molecular docking, natural product, topoisomeraseCite this ArticleTomy Muringayil Joseph, Debarshi Kar Mahapatra. Bacterial …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 2, 2018 · pp. 7–9 Read article
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Neuropathic Potential of Cabazitaxel Comparative to Paclitaxel and Ameliorative Effect of Capsaicin
Abstract: Paclitaxel and cabazitaxel both are the cytotoxic anticancer drugs having microtubule damaging property. The study aims at comparative neuropathic potential evaluation of cabazitaxel against paclitaxel and to assess the efficacy level of intraperitoneally applied capsaicin isolated from Capsicum annuum seed against both paclitaxel and cabazitaxel-induced neuropathy. Neuropathy was evaluated of heat hyperalgesia, cold allodynia, tactile mechanical hyperalgesia and extent of motor incoordination and motor impairment development on mice. Alternate day …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 5, Issue 2, 2018 · pp. 25–38 Read article
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Multifarious Pharmacotherapeutic Perspectives of Some Natural Bromophenol Compounds: In silico Enzyme Inhibitory Potentials
Abstract: The process of drug discovery, design, and development often designated as 3Ds has played enormous role in modern era. The present research investigation includes in silico exploration of possible pharmacological potentials of bromophenol compounds by the aid of Schrodinger Maestro 9.1 software against six pharmacotherapeutic targets; Dipeptidyl peptidase (anti-diabetic), Angiotensin-1-Converting Enzyme (anti-hypertensive), Cyclin-Dependent Kinase-5 (anti-cancer), Protein kinase C (anti-cancer), Lipoxygenase-5 (anti-inflammatory), and Cycloxygenase-2 (anti-inflammatory). The docking scores, referred to as …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 6, Issue 2, 2019 · pp. 24–29 Read article
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IN SILICO EVALUATION OF INHIBITORY POTENTIAL OF SOME COMMERCIALLY AVAILABLE FLAVONOIDS AGAINST BETA- SECRETASE IN THE MANAGEMENT OF ALZHIEMER’S DISEASE
Abstract: In a continuing effort to develop multitargeted compounds as potential treatment agents against Alzheimer's disease (AD), a certain commercially available flavonoids were evaluated against crystal structure of beta-secretase enzyme using in silico docking studies. In this perspective, flavonoids like apigenin, galangin, gallocatechol, genistein, luteolin, myricetin, and theaflavin were selected. AutoDock 4.2 software was used for the in-silico docking studies which possess the principle of Lamarckian genetic algorithm. In the docking …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 6, Issue 2, 2019 · pp. 30–35 Read article
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Potential Application of Retama sphaerocarpa Plant in Pharmaceuticals
Abstract: The aim of this study was to evaluate the phytochemical and biological activity (antibacterial and antifungal) of Retama sphaerocarpa plant and the possibility to use it in pharmaceutical formulations. This plant is traditionally used only as healing remedies because of their antiseptic, antipyretic and antidiarrheal properties. Phytochemical screening of leaves and stems revealed the presence of flavonoids, alkaloids, tannins and steroids. The antimicrobial activity was determined on bacterial strains such …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 3, 2019 · pp. 22–28 Read article
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Graphene Oxide: A Potential Drug Carrier for Cancer Therapy—Review
Abstract: Graphene oxide (GO) is a single or few layer’s sheet derived from graphite using strong oxidizing agents. Graphene oxide possesses outstanding aqueous processability, amphiphilicity, functionalizability, surface enhanced area and fluorescence ability. Hydrophilicity is an important property for mixing the material with ceramic or polymer matrixes while trying to improve their electrical and mechanical properties. Acquiring a promising application in the biomedical area, graphene molecules undergo complex interactions with the biological …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 3, 2017 · pp. 21–31 Read article
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Liquid Chromatography Mass Spectrometer (LC/MS) Profile Revealed Flavonoids with Antioxidant Potential in Butanol Fraction of Gymnema Sylvestre Leaf Extract
Abstract: Gymnema sylvestre (Asclepiadaceae) is widely used in the treatment of several diseases associated with oxidative stress. This study aimed to identify Flavonoids with antioxidant potentials in Butanol fraction of Gymnema sylvestre leaf extract. In vitro antioxidant activity was studied using DPPH and Ferric Reducing Antioxidant Power (FRAP). The results revealed higher radical scavenging activity of 86.53±0.86 in DPPH compared to the control Ascorbic acid with 84.71±0.61 and also similarly in …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 9, Issue 1, 2022 · pp. 26–39 Read article
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Anti-Escherichia coli Potentials of a Novel Chemical Compound 1-(2-hydroxy-1, 2-diphenylethylidene)-3-phenylthiourea
Abstract: Inspiration from the anti-infective excellence (anti-bacterial, anti-fungal, anti-viral, and anti-malarial) of Schiff’s base molecules as well as knowing the rising importance of low-molecular-weight ligands (LMWL), the present research involved the development of novel Schiff’s base compound utilizing very basic laboratory components; 1-phenylthiourea and benzoin using the conventional synthesis technique. The compounds were comprehensively characterized through sophisticated instruments and further screened for anti-microbial activity against pathogenic Escherichia coli (E. coli, MTCC …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 1, 2020 · pp. 9–12 Read article
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A Structure-based Design Approach to Catharanthus roseus Phytoconstituents as Potential Inhibitors of B-Cell Lymphoma 6 Protein
Abstract: Objectives: Lymphoma is a cancerous disease. It develops into millions of people worldwide. Identify the naturally active compounds from Catharanthus roseus, they have multiple values in the medicinal field of Siddha, and Indian Ayurveda are used as a disease-preventing agent. Drug illness prediction, toxicity prediction, statistical information, molecular docking, as well as absorption, distribution, metabolism, and excretion (ADME) analysis are used to predict the fit ligand as a drug. Methods: …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 14–34 Read article
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Harnessing the Medicinal Potential of SwertiaChirata: A Phytochemical Strategy for Controlling Coronavirus Symptoms Like High Fever and Anxiety
Abstract: The current investigation focuses on exploring the therapeutic capacities of SwertiaChirata, colloquially known as Chirata, in managing the symptomatic displays of coronavirus infections. Chirata, a member of the Gentianaceae family, is a distinguished herb extensively used in Ayurvedic and Unani medicinal traditions, acknowledged for its myriad of healing qualities. In addition to its regular use in combating fever and loss of appetite, its prominent antioxidant traits position it as an …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 2, 2023 · pp. 27–31 Read article
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Using Multitarget Molecular Docking to Examine the Antiviral Potential of Clerodendrum Phlomidis against Measles
Abstract: Objective: Measles, a viral disease caused by a member of the Paramyxoviridae virus family, is highly contagious and characterized by a respiratory illness and a maculopapular rash on the skin. Children are the main victims of the illness. In the context of drug development, this study investigates the efficacy of phytocompounds derived from Clerodendrum phlomidis against the target protein of the measles virus. Methods: The 7SKS protein was retrieved from …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 32–42 Read article
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The Impact of Climate Change on Infectious Diseases: Potential Risks and Mitigation Strategies
Abstract: As we confront the pressing challenge of climate change, it's vital to recognize its intertwined connection with infectious diseases. We must now navigate a future that combines strong public health interventions, environmental stewardship, and strong policy actions as we stand at the crossroads of crises. In an attempt to lessen the drastic effects of climate change on the dynamics of disease transmission, this study identifies potential risks and creative solutions. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 21–32 Read article