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152 articles for “lipid”
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Ivermectin: Its Therapeutic Efficacy in the Treatment of COVID-19
Abstract: Over past 35 years the most commonly used anti-helminthic drug is ivermectin. It has showed good impact in treating the parasitic infections. The drug provides an evidence of immune modulatory and anti-inflammatory actions in vitro animal model. Ivermectin belongs to the class of ivermectin and most widely used as an anti-parasitic agent. It is also used in the treatment of internal nematode infections like onchocerciasis, filariasis, and strongloidiasis. For the …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 3, 2021 · pp. 1–5 Read article
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A Review of Psychoendocrine Morbidity: Co-occurring Diabetes Type-II (DIAII), Bipolar II Disorder (BPII), and Obsessive-Compulsive Disorder (OCD)
Abstract: The acute phase of (Bipolar II Disorder) BPII encompasses a psychosis of dramatic mood changes and elevated energy levels often accompanied by co-occurring psychiatric and systemic disorders. The co-occurring disorders (i.e., BPII, DIAII, and OCD) are accentuated, most often by the metabolic imbalances of (Diabetes Type-II) DIAII and sometimes by the psychiatric condition of (Obsessive-Compulsive Disorder) OCD. Increased morbidity and mortality of the co-occurring disorders dominates the chronic course of …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 6, Issue 2, 2016 · pp. 19–23 Read article
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Ameliorating Effect of Vitamin C on Acid Orange 7 Induced Oxidative Stress in the Gill of the Fish, Anabas testudineus (Bloch, 1792)
Abstract: Acid orange 7, an azo dye, was exposed to Anabas testudineus at a sublethal concentration (0.27 g/l) for 24, 72 and 96 h in order to evaluate the antioxidant status in the gill tissue. In addition, vitamin C at 0.55 g/l was exposed for 7 days after the dye exposure. Acid orange 7 decreased the body weight of fish, whereas mucous deposition increased significantly as the first line of defensive …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 3, 2018 · pp. 15–27 Read article
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Hepatoprotective Efficiency of Nigella sativa L. Extract on D-Galactosamine Induced Toxicity
Abstract: The Protective role of Nigella Sativa L. alcoholic extract (NSE) was investigated on D-Galactosamine (DGalN) induced hepatotoxicity in rats. Twenty four adult wistar albino rats were divided into four groups viz Control, D-Galatosamine induced hepatotoxicity, Nigella sativa alcoholic extract and Nigella Sativa alcoholic extract pretreatment prior to the administration of D-Galactosamine. After treatment, the rats were sacrificed, blood and liver samples were collected for determination of Serum Aspartate transaminase (AST), …
Published in Research and Reviews: A Journal of Toxicology · Vol. 1, Issue 1-3, 2011 · pp. 39–44 Read article
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Arsenic Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Arsenic (As) is a metalloid listed in group Va of the periodic chart. It exists in nature in the oxidation states +V (arsenate), +III (arsenite), 0 (arsenic) and −III (arsine). In the aqueous environment inorganic arsenic appears commonly in the oxidation states +V and +III as arsenous acid (As (III)), arsenic acid (As (V)), and their salts. Chronic and acute exposures of arsenic leads to cancer, cardiovascular disease (hypertension and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 2, 2012 · pp. 16–37 Read article
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Molecular Mechanism of Fluoride Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Fluorine (Fl) a member of the halogen family is the most electronegative and reactive of all the elements of the Periodic table. Chronic and acute exposures of fluoride leads to cardiovascular disease (hypertension and atherosclerosis), neurological disorders, gastrointestinal disturbances, liver disease, renal disease, reproductive effects, other health disorders and also affects the antioxidant system in the body. Furthermore, reactive oxygen species (ROS)-mediated oxidative damage is a common malady in fluoride …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 7–34 Read article
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Review on Histological Effect of Lead on Liver and Kidney
Abstract: Our environment can be polluted by environmental toxins which are chemicals and other materials produced largely from industry and its products. There are large numbers of environmental toxicants which are potentially harmful to health. These large numbers of environmental toxicants can be divided into three major categories (heavy metals, air pollutants, and pesticides) and they are commonly studied environmental toxicants. Environmental toxins can be entered into the body by various …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 1, 2020 · pp. 8–29 Read article
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Pyrethroid Mediated Some Macromolecular and Biochemical Changes in Freshwater Teleost
Abstract: Abstract In present investigation, a freshwater fish Channa punctatus was exposed for 21 days to synthetic pyrethroid malathion at sublethal concentrations of 0.007mg L−1 and 0.093 mg L−1 that represented 10% of the 96 h LC50 of the pesticide for this fish. Tissue samples were collected at the end of the experiment and analyzed to determine oxidant/antioxidants status (catalase, LDH, DNA content, protein content, cortisol, etc.) of the fish. Enzyme …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 2, 2020 · pp. 14–21 Read article
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Attenuation of Doxorubicin-induced Hepato- and Nephrotoxicity by Proanthocyanidins from Myrica nagi Bark in Wistar Rats
Abstract: Due to dose-related toxic effects, doxorubicin, a very potent and often used anti-cancer medication, is largely limited. The current research investigated the protective impact of Myrica nagi bark (PMN)-isolated proanthocyanidins on hepato-induced doxorubicin and nephrotoxicity in Wistar rats. The animals were subdivided into six classes of five rats each. Group I got PMN (200 mg/kg, p.o.) for 21 days, Group II received Doxorubicin (DXR) (60 mg/kg, i.p.) once, 48 h …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 19–28 Read article
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An Open Label Randomized Comparative Clinical Study of Safoof-e-Mohazzil versus Atorvastatin in the Cases of Fart-e-Tadassum-Fid-Dam (Primary Hyperlipidaemia)
Abstract: Hyperlipidaemia (Fart-e-Tadassum-Fid-Dam) is a common metabolic disease seen in clinical practice. It is mentioned that increased lipid level is associated with the pathogenesis of atherosclerosis. Theory of hyperlipidaemia meets similarly on the basis of etiology, presentation, complications, patho-physiology and non-pharmacological management with Saman-e-mufrit (obesity). Therefore, it is an important need to provide safe and effective drug from Unani system of medicine for the long term management of hyperlipidaemia. In the …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 1, 2018 · pp. 6–12 Read article
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Development of Antioxidant Based Therapeutics in Unani System of Medicine
Abstract: During the last decades, several studies have examined the potential role of oxidative stress in the development of various diseases like cancer, Parkinson's disease, Alzheimer's disease, atherosclerosis, myocardial infarction, chronic fatigue syndrome etc. Oxidative stress can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Unani system of medicine has a wealth of antioxidants that can …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 3, 2018 · pp. 1–4 Read article
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Phytotherapeutic Potential of Melaleuca: An Integrative Review of Phytochemistry and Antimicrobial, Antifungal, Antioxidant, and Antiviral Mechanisms
Abstract: Melaleuca alternifolia and other species of the Melaleuca genus stand out for the broad spectrum of pharmacological properties attributed to their bioactive compounds, such as monoterpenes, sesquiterpenes, flavonoids, and polyphenols. This study aimed to critically review and analyze scientific evidence produced between 2005 and 2025 regarding the antimicrobial, antifungal, antioxidant, and antiviral activities of Melaleuca, correlating its phytochemistry with molecular mechanisms of action. For this purpose, an integrative literature review …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 · pp. 16–30 Read article