Search
194 articles for “co-infection”
-
Epidemiology of Stomach Cancer in Northeastern States of India: Focusing on Nagaland and the Effectiveness of Screening Programs
Abstract: Stomach cancer represents a critical public health burden in northeastern India, with Nagaland exhibiting the highest age-standardized incidence rate in the country - nearly triple the national average. This elevated risk profile stems from multiple factors including traditional dietary practices (high consumption of smoked meats and fermented foods), widespread Helicobacter pylori infection (affecting approximately 70% of adults), prevalent tobacco/alcohol use, and limited healthcare infrastructure. Despite demonstrated success of endoscopic screening …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
-
Post-Antibiotic Gut Microbiota Recovery in the Rumen: Insights into Colonization Patterns, Population Density, and Diversity Dynamics
Abstract: The post-antibiotic recovery of gut microbiota represents a critical area of research in understanding how microbial communities rebalance and re-establish homeostasis following antibiotic-induced disruptions. Antibiotics, while effective against infections, can cause substantial shifts in gut microbiota, leading to dysbiosis – a state of microbial imbalance that impairs gut health and functions. This recovery process involves multiple complex dynamics, including colonization patterns, population density, and the restoration of microbial diversity. The …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–17 Read article
-
A Molecular Docking Study: Targetting HIV-1 Integrase Protein Against Selected Phytocompounds from Calophyllum Lanigerum
Abstract: Objectives: The most common form of HIV that causes AIDS is HIV-1. The World Health Organization has estimated roughly 75 million plus HIV-1 infections till date and roughly 40 million deaths (as of 2021). Thus, this study was done to identify natural compounds from Calophyllum lanigerum, a medicinal plant largely endemic to South-East Asia, to inhibit the spread of this disease. It did so by using molecular docking methods, Lipinski …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 43–55 Read article
-
In silico analysis of Abrus precatorius L. as a potential agonist of PPARγ : A novel approach to the treatment of diabetes
Abstract: Diabetes mellitus is a chronic disorder that is characterized by a lack of insulin secretion by the pancreas or a defect in insulin action, or both. If diabetes is not controlled, over time it can cause damage to blood vessels and nerves, leading to life-threatening complications such as, kidney damage, heart disease and vision impairment. It can also weaken the immune system, making patients more prone to infection. Although treatments …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
-
Development of a Novel Therapeutic Approach Using RNA Interference for Targeting Viral Genes
Abstract: RNA interference (RNAi) is a ground breaking therapeutic strategy that holds immense promise for targeting viral genes in the treatment of viral infections. This approach leverages the natural gene-silencing mechanisms of RNAi to inhibit viral replication and expression at the molecular level, providing a precise and adaptable method to counteract viral pathogens, including influenza, HIV, and hepatitis viruses. Recent advancements in RNAi technology have enabled the development of highly specific …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 12–22 Read article
-
Tinospora Sinensis Compounds for Zika Virus Targets 5JRZ and 5KVD In Silico Screening: A Potential Approach to Preventing Guillain-Barre Syndrome
Abstract: Objective: GBS is a very rare kind of disease but at the same time, it is very dangerous too. The study estimates that people who are suffering from zika virus infection are more prone to GBS. According to surveys, 1 out of 4000 people got affected by this disease, and the scariest part of this disease is that there is no cure available. In this computational era drug discovery is …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 1–15 Read article
-
A Note on Vaccine Design Using Bioinformatics Methods and Applications
Abstract: Vaccines prevent infectious diseases caused by viruses and bacteria saving millions of lives.It consists of certain agents that resemble disease causative agentsand stimulates our immune system to recognize and fight foreign antigens. Immune function or an immune response is the fundamental basis of the vaccine's mechanism. Vaccines are pharmaceutical derivatives that provide an affordable way to prevent diseases.Various bioinformatics approaches can be incorporated into vaccine design studies and development. Reverse …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 1–9 Read article
-
Trichoderma: beneficial fungus for sustainable agriculture
Abstract: As environmentally beneficial substitutes for chemical pesticides, Trichoderma species are being utilized in agriculture more and more. Disease suppression, increased plant growth, and increased tolerance to environmental stress are just a few advantages they provide. These fungi are used in a wide range of cropping systems and formulations around the world. Their use is growing worldwide, particularly in Asia and Europe. In contemporary crop management, items derived from Trichoderma are …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 25–29 Read article
-
Histoplasma capsulatum (Dimorphic Fungus) in India: Biological Features, Virulence Mechanisms, and Clinical Implications of Histoplasmosis.
Abstract: Histoplasmosis is a systemic mycosis caused by the thermally dimorphic fungus Histoplasma capsulatum. Infection is acquired primarily by inhalation of infectious microconidia and may range from asymptomatic infection to severe disseminated disease. Although histoplasmosis has classically been associated with the river valleys of the Americas, it is being increasingly recognized in Asia, including India, where it frequently mimics tuberculosis, leishmaniasis, lymphoma, and leprosy, resulting in delayed diagnosis and treatment. Cutaneous …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 38–48 Read article
-
Isolation and Evaluation of Aspergillus Niger : A Fungi Implicated in Infectious Diseases and its application as potential Biofertilizer
Abstract: In the quest to improve the agronomic effectiveness of Rock Phosphate (RP), a widely available and cost-effective phosphate fertilizer, this study aimed to overcome its limited solubility by isolating fungal strains capable of solubilizing rock phosphate. Soil samples were collected from Garhmukteshwar, Hapur, for the isolation process. Among several isolates, three strains exhibited the highest rock phosphate solubilization within a seven-day timeframe, coinciding with a significant decrease in soil pH. …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 29–34 Read article
-
Detection of Pneumonia in COVID-19 Patients Using X-ray Images
Abstract: This study explores the use of chest X-ray image analysis and deep learning methods to identify pneumonia in COVID-19 patients. Due to the pandemic, Proper as well as immediate examination of COVID-19 is now essential for patient care and disease control. This study proposes a novel approach that uses convolutional neural networks (CNNs) to automatically predict pneumonia in COVID-19 patients using chest X-ray images. In this study, an X-ray of …
Published in International Journal of Radio Frequency Innovations · Vol. 1, Issue 1, 2023 · pp. 13–23 Read article
-
An Evaluation of the Impact of a Nurse-Led Program on Knowledge and Practices Related to Needle Stick Injury Prevention Among 2nd Year B.Sc. Nursing Students at the College of Nursing, PT. B.D. Sharma PGIMS, Rohtak
Abstract: Healthcare workers and nursing students frequently face accidental occupational exposures while caring for patients, with needle stick injuries being the most common form of exposure in healthcare settings. These injuries pose a significant risk of infections. This study aimed to evaluate the awareness and practices related to the prevention of needle stick injuries among second-year B.Sc. Nursing students, assess the effectiveness of a nurse-led intervention in enhancing their knowledge and …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 28–66 Read article
-
Immunological Biomarkers and Epidemiological Evaluation of Lymphatic Filariasis Elimination Efforts in Osun State, Nigeria
Abstract: Lymphatic filariasis (LF) remains a neglected tropical disease affecting millions globally, despite extensive elimination efforts. While the interruption of transmission is a key goal, the long-term immunological effects on individuals with existing complications like elephantiasis remain poorly understood. This study assessed the current transmission status of LF and the haematological profiles of infected individuals across selected Local Government Areas (LGAs) in Osun State, Nigeria. A total of 7,388 individuals from …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 22–30 Read article
-
Uncovering the Comparative Efficacy of Antiviral Drugs and Caricapapaya Phytocompound as VP2H inhibitors in Ebola virus: An Insilico Molecular Docking Analysis
Abstract: The Ebola virus is a fatal disease that transmits from wild animals to humans. Infected individuals' body fluids such as spit, blood, perspiration, faeces, blood, saliva, breast milk, sperm, or fomites can transmit Ebola. Adhesion to cell membranes and penetration into the host organism are essential aspects in viral growth. The presence of VP24, as well as nucleoproteins and structural proteins, is necessary for nucleocapsid formation and integration. The inhibition …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 62–78 Read article
-
Progression in multi-omics and immunological research on host-parasite interactions: Transcriptomics, proteomics, genomics, metabolomics, and immune responses
Abstract: The interaction occuring between hosts and parasites is a quick and multi step-complex biological process that tries to influence disease outcomes. In recent years, multi-omics approaches, such as transcriptomics, proteomics, genomics, metabolomics, and immunological studies, have gathered substantial eye in dissecting these interactions at a microscopic level. These techniques enable a vast understanding of the molecular structures involved in parasitic infections and host defense mechanisms. This article reviews the advancements …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
-
The Effectiveness of Honey Application for Oral Mucositis in Cancer Patients: A Review of Randomized Controlled Trials
Abstract: Background: Oral mucositis (OM) is a prevalent and distressing adverse outcome of cancer therapies, including chemotherapy and radiation therapy. It is an inflammatory ailment that impacts the mucous membrane inside the mouth, tongue, gums, and throat. OM can cause pain, discomfort, difficulty swallowing, and in severe cases, it can lead to infection and delayed cancer treatment. Although there are various treatments available, such as painkillers, anti-inflammatory drugs, and topical anesthetics, …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 32–39 Read article
-
Emerging Digital Trends in Virology Software: Optimizing Viral Discovery, Surveillance,and Patient Management.
Abstract: Virology and antiviral therapeutics are being reshaped by rapid advances in computational tools, automation platforms, and virus-focused digital health applications. Software systems now span the entire virology value chain, from in silico viral target identification and antigen design, to AI-supported clinical trial management for vaccines and antivirals, to post-marketing pharmacovigilance and patient-facing mobile tools. This review examines current and emerging software trends relevant to virus studies, emphasizing applications in viral …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 29–38 Read article
-
Climate Change and Economic Vulnerability in Pakistan: An Analysis of Future Risks
Abstract: This paper discussed effects of climate change on economic vulnerability in Pakistan. The findings show that the nation's economy is negatively impacted by climate change. Poverty, unemployment, crime, forest fire, diseases, migration, internal displacement, urban slum, flood etc. will be increase in future due to climate change. Biodiversity and economic balance will be disturbed. Food production, electricity supply, basic infrastructure will be badly affected. Development activities in water resources, as …
Published in International Journal of Climate Conditions · Vol. 1, Issue 2, 2024 · pp. 39–46 Read article
-
Nutrition Induced Gut Microbiota Modulation in Food Animals: Implications for Viral Susceptibility, Shedding and Transmission Dynamics for Sustainable Development
Abstract: The gut microbiota has emerged as a central mediator linking host nutrition, immune competence, and vulnerability to viral pathogens in food animals. Diet is a primary driver of microbial community structure and function, influencing metabolite production, intestinal barrier integrity, and systemic antiviral immunity. Accumulating evidence indicates that nutrition induced modulation of the gut microbiota can substantially alter viral susceptibility, replication, and shedding patterns, with downstream effects on transmission dynamics within …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 46–56 Read article
-
Revolutionizing Anti-Allergy Medications: A Comprehensive Review of Target Discovery and Medicinal Chemistry
Abstract: Above the past few decades, the prevalence of allergy illnesses has been steadily rising, impacting 20–30% of the world's population. Multiple targets are involved in allergic reactions to infections of the skin, digestive tract, and respiratory system. Developing medications with a good curative efficacy and minimal side effects while utilizing novel multi-targets and processes in accordance with the clinical features of various allergic populations and allergens is the primary challenge …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 1, 2023 · pp. 49–54 Read article