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227 articles for “Genetics of the Disease”
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Wiskott-Aldrich Syndrome: A Comprehensive Guide
Abstract: Wiskott-Aldrich Syndrome (WAS) is an uncommon genetic disorder inherited through the X chromosome, marked by a combination of immune system deficiencies, eczema, and low platelet counts. This syndrome primarily affects males, leading to significant morbidity and mortality due to recurrent infections, bleeding complications, and autoimmune diseases. Mutations in the WAS gene disrupt the production of the Wiskott-Aldrich Syndrome protein (WASp), crucial for the functioning of immune cells and platelet formation. …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 39–46 Read article
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Chronic Obstructive Pulmonary Disease (COPD) in Younger Adults: Challenges and Considerations – A Review
Abstract: Chronic Obstructive Pulmonary Disease (COPD) phenomenon rapidly converting into chronic significant health issues for many young adults. A disease calculated for older age gives way to early-onset COPD, which creates new issues for diagnosing and treating the illness and even interacts with the quality of life. The article reviews the epidemiology, risk factors, pathophysiology, clinical presentation, and treatment considerations related to this set of conditions. From those risk factors, early-onset …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 08–19 Read article
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Virulence Factors in pathogens :mechanisms of infection & disease progression
Abstract: Pathogens, like bacteria, viruses, fungi, and parasites, have evolved specialized tools – known as virulence factors – that help them infect hosts, escape the immune system, and cause disease. These factors play a key role in determining how severe an infection becomes, how quickly it spreads, and how the body responds. Some pathogens use adhesins to stick to host cells, while others produce toxins that damage tissues or disrupt normal …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 6–11 Read article
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Diet-Driven Enhancement of Immune Resilience, Disease Resistance, and Performance: Mechanistic Insights, Nutritional Interventions, and Implications for Sustainable Dairy Development
Abstract: This review synthesizes current knowledge on how dietary strategies can strengthen immune resilience, improve disease resistance, and enhance productive performance in dairy systems while advancing sustainable development. Immune function in dairy cattle is profoundly influenced by nutrition, with energy, protein, essential amino acids, fatty acids, vitamins, minerals, and bioactive compounds playing critical roles in shaping both innate and adaptive immune responses. Suboptimal nutrition impairs immune competence, increases susceptibility to infectious …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 15–24 Read article
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The Role of Artificial Intelligence in Mental Health: Applications in Neurodegenerative Disorders
Abstract: Artificial intelligence (AI) has significantly changed many aspects of medical care, particularly the early evaluation, therapy, and management of neurodegenerative illnesses like Alzheimer's, disease, Parkinson's diseases, and Huntington's diseases. The current research explores the application of AI in mental health with respect to neurological disorders, especially advancements in cognitive examination, neuroimaging analysis, predictive modeling, and customized therapy modalities. Artificial intelligence (AI) systems have shown enormous potential in detecting minute biomarkers …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 3, 2025 · pp. 34–40 Read article
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Gut Feelings: Unravelling the Secrets of the Microbial Universe Within
Abstract: The human digestive system hosts a varied and dynamic community of microorganisms, commonly known as the gut microbiota. This complex community, which includes various organisms such as bacteria, archaea, viruses, and fungi, is essential and important for numerous bodily functions such as metabolism, immune response, and cognitive development. The composition and vast diversity of the gut microbiome are shaped by diet, lifestyle, and genetic factors. Disruptions in this balance, known …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 21–33 Read article
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Non-Small Cell Lung Cancer: Types, Pathogenesis, Diagnosis, and Novel Therapeutic Strategies
Abstract: Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer, accounting for over 85% of all cases globally. It remains one of the primary causes of cancer-related death due to its rapid progression, few early symptoms, and late detection. The three main forms of non-small cell lung cancer (NSCLC) are adenocarcinoma, squamous cell carcinoma, and giant cell carcinoma; each has a unique histology, prognosis, and response to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 07–22 Read article
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Review of Breeding for Ascochyta Blight [Phoma exigua var. diversispora (Bubak) Boerema] Resistance in Common Bean
Abstract: AbstractBean ascochyta blight, caused by Phoma exigua var. diversispora, is an important disease of the common bean (Phaseolus vulgaris L.) throughout Rwanda. It is known to cause total crop losses, especially under humid conditions and low soil fertility. This review focuses on the taxonomy and agronomy of the common bean. It discusses the origin and diversity of beans, and highlights the production constraints. The review dwells on studies on genetic …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 6, Issue 2, 2017 · pp. 38–53 Read article
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COVID and Computational Biology: A Review
Abstract: The (COVID-19) Corona Virus 19 Disease is infecting millions of people and made several billions to stay at home under Lockdown. The disease has caused global pandemic. The nano-sized virus is threatening the entire human race. It is posing mere burden to the Public, Government, and the health care sectors. The COVID-19 virus is a novel virus, after deep sequencing from samples done by several researchers, and scientist form the …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 1, 2021 · pp. 3–5 Read article
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How Scientists Look for New Pathogens Before They Spread
Abstract: Emerging infectious illnesses are a persistent danger to global health. They often come from unexpected places, such wildlife reservoirs, changes in the climate, or human activities. Finding new diseases before they create epidemics is one of the biggest problems in modern epidemiology. This article talks about how scientists use genetic monitoring, field sampling, and real-time data processing to find, track, and describe new infectious organisms in a way that works …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 11–17 Read article
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Clinical Study of Role of Rasayana as a Pre adjuvant and Post Treatment of Chemotherapy in the Management of Carcinoma
Abstract: Integrative oncology is a novel form of medical theory which views cancer not merely as an accumulation of genetically transformed immature cells, but sum total of feelings, images, actions evoked by cancer. Not only by those afflicted with the disease, but also by their loved ones. This has been very well understood by Ayurveda. The important tool to manage the adverse reaction is Rasayana. Rasayana through their nutrient value improves …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 1, 2022 · pp. 5–13 Read article
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It is Not an Aberration, It is Fragment of our Correlated Viral Age
Abstract: Corona viruses are a cluster of allied contamination of germs that is originated in creatures and birds. In humanoid, corona viruses are rooted through respiratory, wheezing zone which infects the body and fluctuates from lightest to life threatening stage. The incurable classification of diseases are Severe acute respiratory syndrome-related corona virus (SARS), Middle East respiratory syndrome-related corona virus (MERS) and COVID-19. Till now, this contaminated germ disease does not have …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 8, Issue 2, 2021 · pp. 43–49 Read article
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Vaccination in the Era of Precision Medicine: Tailoring Immunization Strategies for Individual Risk Profiles
Abstract: The introduction of precision medicine has caused a paradigm change in the vaccine landscape. Conventionally, vaccination programmes have been homogeneous, targeting immunity at the population level without taking into consideration the individual differences in immune response and vulnerability to diseases that can be prevented by vaccination. However, a more individualised approach to immunisation has been made possible by current developments in genetics, immunology, and data analytics. Within the context of …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 32–47 Read article
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A Review on The effect of Polycystic Ovary Syndrome on some Hormonal and Metabolic Disturbances in Women
Abstract: Polycystic ovary syndrome (PCOS) is a common hormonal condition that affects women of reproductive age. It usually begins to appear during adolescence. The ovaries produce an abnormal amount of "androgens", which are male sex hormones that are usually found in women in small quantities. Ovarian syndrome causes hormonal imbalances, irregular menstrual cycles, increased cysts in the ovaries, in addition to hair growth all over the body, acne, and pain in …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 21–28 Read article
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Systemic Lupus Erythematosus Revisited: A Milestones in Classification, Mechanistic Insights on Pathogenesis, Diagnosis, and Evolving Treatment Paradigms
Abstract: Systemic lupus erythematosus (SLE) is a prototypic, multi-systemic chronic inflammatory autoimmune disorder characterized by extreme clinical heterogeneity and the potential to involve virtually any organ or tissue. The condition is driven by a fundamental breakdown in immune tolerance, resulting in the overproduction of pathogenic autoantibodies and the formation of immune complexes that precipitate widespread inflammation and organ damage. This review aims to provide an exhaustive synthesis of recent developments in …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 3, 2026 Read article
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Smart Innovations for Biodiversity Conservation
Abstract: Biodiversity, or the vast diversity of life on Earth, is rapidly vanishing. In the last few decades, there has been a massive loss. Several animal and plant species have declined in recent decades. At an alarming rate, hundreds of thousands of acres of forests have been devastated. Several blue whales, polar bears, pandas, and other well-known animals starved to death. Many yet-to-be-discovered species are also in jeopardy. In recent years, …
Published in Journal of Remote Sensing & GIS · Vol. 12, Issue 3, 2021 · pp. 26–29 Read article
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Assessment of Diseases on Wheat Rusts Trap Nursery in Southern Ethiopia
Abstract: The rusts diseases caused by Puccinia, species are the major biotic constraints in many wheat producing areas of Ethiopia. The present study was conducted in 2015 and 2016 main growing season to observe commercial varieties and differential lines of bread and durum wheat for their resistance to the existing race composition. About 200 wheat varieties and lines were included in trap nursery for evaluation of triple rust was investigated under …
Published in Research & Reviews : Journal of Botany · Vol. 11, Issue 3, 2022 · pp. 27–37 Read article
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Early and Premature Menopause
Abstract: For the sake of communal welfare and gender equality, women's health must be improved. The end of reproductive life is marked by menopause, which usually happens between the ages of 45 and 55 and is impacted by lifestyle, environmental, and genetic variables. Social injustices, poor diet, and reproductive stressors are associated with early menopause (before 45), which raises the risk of osteoporosis, cardiovascular disease, cancer, and cognitive decline. Decreases in …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 3, 2026 Read article
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The Future is Bioengineered: Consequences, Directions, and Regulation
Abstract: Biotechnology is changing how people interact with health, life, and the environment very quickly. This article talks about how new tools in genetic engineering, synthetic biology, and bioinformatics are making it possible for scientists to build and change biological things with more accuracy than ever before. Biotechnology is changing several fields, from making personalised medical treatments and disease-resistant crops to making biofuels and materials that break down naturally. The talk …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 40–49 Read article
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Pathways of Periodontal Disease and Alveolar Bone Loss in Type II Diabetes
Abstract: or poorly-controlled type II diabetes often exhibits a high morbidity of periodontal pathology. Food impaction in defective restorations or open proximal contacts often leads to infection, carious lesions, periodontitis, alveolar bone loss and often tooth loss. An iatrogenic injury occurs when restorations are defective, fractures, or have open proximal contacts and are not planned to be repaired or replaced. In addition to having poor therapeutic outcomes, defective restorations or open …
Published in Research and Reviews: A Journal of Dentistry · Vol. 4, Issue 3, 2013 · pp. 28–35 Read article