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1930 articles for “3-acetyl-7-bromo-2H-chromen-2-one” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Emerging Therapeutic Discovery Against Escherichia coli Infection by Rational Inhibition of Fatty Acid Responsive Transcription Factor: Theoretical Molecular Investigations of Some Metabolites as Inhibitors of Fatty Acid Metabolism Protein
Abstract: For the discovery of effective agent for overcoming resistance against Escherichia coli (E. coli) bacteria by modulating Fatty Acid Metabolism Protein (FadR)—a Fatty Acid Responsive Transcription Factor. The present study involved discovery of some metabolites of furan, furan-2-yl, macrolactin, and chromene scaffold via in silico structure-based drug design (SBDD) technique by utilizing the Maestro 9.1 software. The study will provide clues, motivate, and throw light on imperative aspects for the …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 3, 2018 · pp. 1–7 Read article
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Ramus Condyle Unit Reconstruction Using L-Shaped Ramus Osteotomy in Temporomandibular Joint Ankylosis
Abstract: Aim and Purpose: To evaluate the feasibility of the L-shaped osteotomy in reconstructing the Ramus Condyle Unit (RCU) after gap arthroplasty in patients with temporomandibular joint (TMJ) ankylosis. Objectives: To evaluate the efficacy of the above procedure by evaluating the increase in mouth opening, by assessing the resorption of the newly reconstructed RCU, by assessing any occlusal disturbances, deviation upon mouth opening and obstructive sleep apnoea, caused by decrease in …
Published in Research and Reviews: A Journal of Dentistry · Vol. 9, Issue 1, 2018 · pp. 1–10 Read article
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Histopathological Findings of Endometrium and its clinico-pathological co-relation
Abstract: Background: Endometrial diseases are ranked among the most common gynecological disorders that affect women globally. These diseases cut across all age groups and contribute significantly to increased morbidity and mortality. Aim: To establish a database with respect to histopathological patterns and frequencies of endometrial diseases in women of various age groups. Materials and Methods: This prospective study was conducted in a Tertiary care Hospital in Sangli (Maharashtra) for a period …
Published in Research and Reviews: A Journal of Health Professions · Vol. 7, Issue 3, 2017 · pp. 33–38 Read article
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Parental Response Towards Substance Using Children: Pilot Study
Abstract: The study was conducted to explore parental responses towards their children, who were recognized Substance Users in a treatment programme. A structured questionnaire was provided to the involved parents, who self-administered it during a single session each, after due discussion and explanation by the researcher. Appropriate consent was taken from the participants. A sample size of 35 patients at Kripa Foundation centre was selected through ‘Snowball Sampling’, from different areas …
Published in Research and Reviews: A Journal of Health Professions · Vol. 7, Issue 2, 2017 · pp. 47–63 Read article
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Assessment of Knowledge, Attitude, Practice and Associated Factors of Emergency Contraceptive Pills among Female Youths in Mekelle City, Tigray Region, North Ethiopia
Abstract: For girls and young women aged 15–19, pregnancy and childbirth is the number one killer. It’s the cause of 50,000 deaths of teenage girls every year. Ensuring that adolescent girls are able to use suitable contraception to delay the age at which they first become pregnant is a key part of the family planning challenge. Around 16 million girls between the ages of 15 and 19 give birth each year. …
Published in Research and Reviews: A Journal of Health Professions · Vol. 5, Issue 1, 2015 · pp. 7–21 Read article
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Clinical Spectrum and Prognosis of Patients with Septic Shock
Abstract: Septic shock is the leading cause of mortality in hospital patients. Closer observation and early treatment can influence the outcome. The present study is undertaken to study the pattern of sepsis and the factors affecting morbidity and mortality in adult patients with septic shock in the ICU. Adult patients admitted in ICU, Mamata General Hospital, Khammam, with diagnosis of sepsis during one-year period from August 2012 to September 2013 were …
Published in Research and Reviews: A Journal of Health Professions · Vol. 4, Issue 1, 2014 · pp. 1–4 Read article
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Prevalence of Musculoskeletal Disorders in Cricketer
Abstract: The study's goal was to determine the prevalence of musculoskeletal diseases in joints and the joints in human body that are most commonly involved in recreational cricket players. Methodology: With the help of a modified Nordic Musculoskeletal Questionnaire the musculoskeletal disorders in 100 recreational cricket players, encompassing both men and women in the 18–26 age range, was conducted. Result. Prevalence of Musculoskeletal Disorders in recreational cricket players during last 12 …
Published in Research and Reviews: A Journal of Health Professions · Vol. 13, Issue 2, 2023 · pp. 20–26 Read article
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Evaluate the effectiveness of nurse led interventions on knowledge and practice regarding nursing care of chest tube drainage among nursing personnel’s working at medical and surgical wards of PGIMS Rohtak Haryana
Abstract: Introduction: The present study was conducted to determine the nursing personnel’s level of knowledge and practice the care of chest tube drainage to improve the quality of nursing care. A chest tube insertion is surgical procedure in which a hollow, flexible drainage tube is inserted through the side of the chest into the plural space in order to drain the plural cavity air, blood, pus or lymph. The water seal …
Published in Research and Reviews: A Journal of Health Professions · Vol. 13, Issue 3, 2023 · pp. 84–90 Read article
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Assessment of Adherence to Antiretroviral Therapy Among Art Users in Jimma University Specialized Hospital, Jimma Zone, Oromia Region, South West Ethiopia
Abstract: Background: HIV-associated morbidity and mortality gets substantially reduced with antiretroviral therapy (ART). Antiretroviral treatment efficacy exhibits significant inhibition of viral replication as well as viral load resulting in significant decrease in viral particles to a level where it becomes undetectable in the blood of HIV infected individuals. But, antiretroviral therapy (ART) requires high-level (>95%) adherence and adherence to antiretroviral therapy has been correlated strongly with HIV viral suppression, reduced rates …
Published in Research and Reviews : A Journal of Immunology · Vol. 8, Issue 1, 2018 · pp. 14–21 Read article
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Prevalence of HIV Associated Neuro-cognitive Deficit among HIV Positive People in Ethiopia: A Cross Sectional Study at Hawassa University Comprehensive Specialized Hospital
Abstract: Background: HIV/AIDS is a common infection in sub-Saharan Africa which is also associated with neurocognitive impairment and psychological. Even if HAART reduces HIV-associated neurocognitive disorders (HAND) by approximately 60 percentage, over 8 million HIV-infected adults in sub-Saharan Africa will be cognitively impaired at some level. This study aimed to assess prevalence and factors associated with neurocognitive impairment among adults living with HIV/AIDS at Hawassa University comprehensive specialized hospital, Ethiopia. Methods: …
Published in Research and Reviews : A Journal of Immunology · Vol. 8, Issue 3, 2018 · pp. 13–18 Read article
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Characterization of a Broadly Specific LPS-Neutralizing Single Domain Antibody
Abstract: Gram negative endotoxaemia or sepsis remains a lethal challenge to humans and animals, globally. Single domain antibodies (dAbs) have emerged as therapeutic biologics for challenging antigens such as lipopolysachharide (LPS). The present study characterized a broadly specific LPS-neutralising dAb produced from phage display library from LPS-immunized Indian desert camel, for its sequence validation with mass spectrometry. Also, the dAb clone 26 was subjected to co-crystallisation with LPS, extracted from E. …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 1, 2017 · pp. 1–7 Read article
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Mothers Practice and Associated Factors on Kangaroo Mother Care, in Mekelle City Hospitals Tigray, North Ethiopia: A Cross-Sectional Survey
Abstract: Kangaroo mother care (KMC) is a special way of holding low birth weight, preterm and hypothermic babies with skin-to-skin contact between the mother and the newborn in a position like a kangaroo. Most neonatal units in the world do not has appropriate space and material to offer a comfort to mothers providing a continuous KMC. In Ethiopia, KMC has not expanded as broadly as we hoped. To assess the practice …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 1, 2016 · pp. 21–31 Read article
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A Study on Demographic Patterns of Drowning Cases in the Medicolegal Autopsies
Abstract: Drowning is a leading global killer. It is a serious and neglected public health threat claiming the lives of 372000 people a year worldwide. In Barpeta district of Assam, drowning cases were relatively more because water resources are in abundance. The objective of study is to find out the demographic pattern and to identify the causative factors. In the study, drowning cases brought for autopsy in the FAAMCH, Barpeta, during …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 3, 2016 · pp. 10–12 Read article
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A Study of Hanging Cases in Barpeta District
Abstract: Hanging is a violent form of asphyxial death. It is widely accepted as a method of suicide due to its relative painless and rapid death. The rate of suicidal hanging cases is increasing day by day. The objective of study is to find out its demographic pattern, ligature material commonly used by the victims, post-mortem findings and to identify the causative factors. In this study of hanging cases brought for …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 3, 2016 · pp. 13–16 Read article
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Neonatal Sepsis: A Study on Isolated Pathogens and Their Susceptibility Pattern at Tertiary Care Hospital in Rural Setting
Abstract: Neonatal sepsis is one of the most important causes of infant mortality and morbidity. In spite of availability of broad spectrum antibiotics, treating sepsis has become a challenge due to emergence of resistant strains from time to time. The present study is aimed at to isolate the organisms causing sepsis in neonates and their antibiotic susceptibility patterns. From April 2013 to June 2014, 167 blood samples were collected from clinically …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 2, 2015 · pp. 11–15 Read article
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History of Low Back Pain during Previous Pregnancy Had an Effect on Development of Low Back Pain in Current Pregnancy Attending Antenatal Care Clinic of University of Gondar Hospital, Northwest Ethiopia
Abstract: Low back pain (LBP) is one of the most common disorders associated with pregnancy. It often causes considerable physical dysfunction, poor work performance and absenteeism. Despite this problem, evidence found in attempting magnitude and associated factors are scarce in Ethiopia. Objective of this study is to assess the associated factors and prevalence of low back pain among pregnant women’s who are attending antennal clinic. A total of 300 pregnant women …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 3, Issue 3, 2014 · pp. 37–44 Read article
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Evaluation of the Effect of Zinc Supplementation on Glycemic Control and Lipid Profile in Normoglycemic and Streptozotocin-induced Type-2 Diabetic Rats
Abstract: Diabetes mellitus is a chronic, progressive disease, which is accompanied by multiple complications. Hyperglycemia and dyslipidemia are common complications of diabetes mellitus. The current approaches for treatment of diabetes are mostly dependent on insulin and other oral standard drugs, which have their own put falls. Thus, micronutrients supplementation is gaining momentum as the quest for management of diabetes continues. Certain micronutrients increase insulin synthesis secretion and insulin sensitivity thereby improve …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 2, 2016 · pp. 41–51 Read article
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Commonest Mode of Suicide in Jorhat District—One Year Retrospective Study
Abstract: One who succeeds in completing the act of suicide, has nothing to bother about and it is only the survivors who are the bear the consequence. Society must identify the potential cases of suicide prone and help and treat them in time irrespective of the method they apply to commit it. The modes of suicidal deaths in an area reflect the socio-economic status and mental health status of the population …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 6, Issue 2, 2017 · pp. 1–4 Read article
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Knowledge, Attitude and Practices of Infant and Young Child Feeding among Mothers/Caregivers Tigray, Ethiopia
Abstract: Background: Foetal life and early childhood years are the phases when growth and development are maximum, coinciding with a period of great vulnerability to sub-optimal environment. Nutrition during the entire life cycle is a key driver of growth and development. Children <2 years are the most vulnerable segment of the community. Appropriate evidence-based feeding practices are essential for attaining and maintaining proper nutrition and health. Objective: The aim of the …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 6, Issue 2, 2017 · pp. 29–40 Read article
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Coronary Risk Reduction Discharge Training Programme (CRR-DTP) on Selfcare Behaviour Among Patients with Percutaneous Coronary Intervention (PCI): A Randomized Controlled Trial
Abstract: AbstractObjective: The study was conducted with an objective to assess the effectiveness of coronary risk reduction discharge training programme (CRR-DTP) on self-care behaviour among patients with percutaneous coronary intervention (PCI). Methods: A randomized control trial was conducted in Jan 2017 in HDHI, Ludhiana. 60 patients were selected on the basis of convenience sampling technique and randomly allocated to experimental (30) and control group (30). Coronary risk reduction discharge training programme …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 2, 2020 · pp. 41–49 Read article