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401 articles for “profiling”
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Antibacterial Activities of Medicinal Plant Leaves Extract Against Isolated Escherichia coli Bacteria from Different Water Sources
Abstract: Objective: Escherichia coli are the most common pathogenic bacteria to accountable for food and waterborne illness. Therefore, in this way the study was conducted to resolve the occurrence of E. coli bacteria from different water sources in around Tamil Nadu along with to determine their antibiotic resistance profiles. Methods: Water samples were analysed for the presence of E. coli bacteria using specific agar media Eosin Methylene Blue and McConkeys. Colony …
Published in Research and Reviews: A Journal of Microbiology and Virology Read article
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Tiryaq-E-Arba (A Poly Herbal Unani Formulation) in Fighting Against COVID-19 Like Conditions–Unani Perspective
Abstract: Coronavirus disease 2019 (COVID-19) is a pandemic disease of modern time with unique and rapid transmission rate and affected almost all the nations without respecting any border. World Health Organization stated it is an infective disease and pandemic. The coronavirus disease 2019 (COVID- 19) which created in Wuhan, China, has now spread to 192 countries and organizational regions infecting nearly 800,000 persons of all ages as of 31 March 2020. …
Published in Research & Reviews : Journal of Herbal Science Read article
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A Structure-based Design Approach to Catharanthus roseus Phytoconstituents as Potential Inhibitors of B-Cell Lymphoma 6 Protein
Abstract: Objectives: Lymphoma is a cancerous disease. It develops into millions of people worldwide. Identify the naturally active compounds from Catharanthus roseus, they have multiple values in the medicinal field of Siddha, and Indian Ayurveda are used as a disease-preventing agent. Drug illness prediction, toxicity prediction, statistical information, molecular docking, as well as absorption, distribution, metabolism, and excretion (ADME) analysis are used to predict the fit ligand as a drug. Methods: …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 14–34 Read article
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A Study to Assess the Impact of Infertility on Marital and Sexual Satisfaction among Infertile Women Visiting Selected Infertility Clinics of City Ludhiana, Punjab
Abstract: Infertility has been described as a stressor and a life crisis for infertile women, which results in a lower marital and sexual satisfaction. More dissatisfaction is felt by infertile women, and both direct and indirect negative effects on the marriage are brought on by stress connected to infertility and its treatment. Having social support from family, a partner, and friends can help infertile women cope with a variety of stressors …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 7–12 Read article
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Quality of Sleep Among Patients with Chronic Renal Failure
Abstract: Renal failure is the partial or complete impairment of kidney function. Inability to eliminate metabolic waste products and water, along with functional disruptions in all bodily systems, result in the condition known as renal failure. Renal failure can be categorized as either acute or chronic. Chronic renal failure refers to the gradual and irreversible deterioration of the nephrons in both kidneys. It is characterized by either kidney damage or a …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 22–28 Read article
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In Silico Analysis and Docking Study of the Active Phyto Compounds of Ginkgo Biloba Against Alzheimer's Amyloid-Beta Protein
Abstract: Objective: Alzheimer's disease, an age-related progressive neurological condition, arises due to the accumulation of amyloid-beta protein within the brain. In this study, an attempt was made to explore the potential of natural compounds derived from Ginkgo, known for their diverse medicinal properties, in the prevention of the disorder by employing molecular docking techniques, conducting drug-likeness prediction assessments, and performing ADME analysis. Methods: Amyloid beta protein was retrieved from the PDB …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 Read article
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TiO2 Refined Flux Provides Significant Impact on Saw Bead Shape, Particle Size, and Hardness
Abstract: This experiment is very interested in how adding titanium dioxide powder to submerged arc welding on low alloy steel plates affects the bead geometry, grain size, and hardness. The commercial fluxes were combined with powdered titanium dioxide at varying concentrations (2.5%, 5%, 7.5%, 10%, and 12.5%). No changes were made to the welding process parameters despite the variety of welding situations. It has been shown that the inclusion of titanium …
Published in Journal of Polymer & Composites · Vol. 11, Issue 4, 2023 · pp. 70–80 Read article
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A Molecular Docking Study: Targetting HIV-1 Integrase Protein Against Selected Phytocompounds from Calophyllum Lanigerum
Abstract: Objectives: The most common form of HIV that causes AIDS is HIV-1. The World Health Organization has estimated roughly 75 million plus HIV-1 infections till date and roughly 40 million deaths (as of 2021). Thus, this study was done to identify natural compounds from Calophyllum lanigerum, a medicinal plant largely endemic to South-East Asia, to inhibit the spread of this disease. It did so by using molecular docking methods, Lipinski …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 43–55 Read article
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Dimensionality Reduction Techniques and their Applications in Cancer Classification: A Comprehensive Review
Abstract: Dimensionality reduction techniques have become a vital tool in the investigation of high-dimensional data like gene expression profiles in cancer research. Here is a review, we deliver a comprehensive overview of dimensionality reduction techniques and their applications in cancer classification. Firstly, we introduce the concepts and approaches of dimensionality reduction, and after that, we explore several methods for decreasing dimensionality. These techniques include Linear Discriminant Analysis (LDA), Principal Component Analysis …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 35–45 Read article
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Revealing the Effect of Swift Carbon Ion Beam on Radiation Sensitivity of Radio-frequency Magnetron Sputtered Grown Alumina Thin Films
Abstract: Regarding targeted treatment, hadron therapy is beneficial than conventional radiotherapy based on X rays/gamma rays due to characteristic energy loss profile of energetic charged particle during ion matter interaction. In this regard, dose monitoring and its precise measurement with spatial accuracy are very crucial. Thermoluminescence (TL) based thin film radiation dosimeter has the potential to serve this purpose. In hadron therapy, use of swift carbon ion beam is found to …
Published in Journal of Polymer & Composites · Vol. 11, Issue 7, 2023 · pp. 23–29 Read article
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Effect of Fillet Radius on Bending Stress in Helical Gear using FEA
Abstract: A well-optimized change in root fillet radius could greatly benefit helical gear operation by providing a smoother transmission with less impact and noise. The fillet area of the gear root is an area of extensive bending stress concentration. An increase in fillet radius for helical gears is considered to minimise the bending stress at the gear tooth's base. This paper develops appropriate models of various gear tooth profiles of the …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 129–136 Read article
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Designing a Novel Insider Threat Model for Enhanced Cybersecurity
Abstract: Designing a novel insider threat model is a critical imperative in the realm of cybersecurity. As organizations face an ever-expanding threat landscape, insider threats, whether deliberate or inadvertent, present a formidable challenge to the safeguarding of sensitive data and critical assets. This abstract encapsulates the significance, challenges, and innovations inherent in crafting an effective insider threat model for enhanced cybersecurity. The necessity for novel insider threat models arises from the …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 2, 2023 · pp. 24–27 Read article
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Zero Trust Security Governance by Utilizing Identity and Access Management
Abstract: The Zero Trust Paradigm, a more stringent approach to network security, operates on the fundamental concept of “Never Assume, Always Authenticate.” It is currently being implemented in different countries to align with their national cybersecurity and access management governance policies. The differentiation of these Zero Trust systems is contingent upon factors such as awareness, infrastructure, expenses, and security demand. Additionally, the identity-based access management models within the Zero Trust system …
Published in International Journal of Mobile Computing Technology · Vol. 1, Issue 2, 2023 · pp. 6–17 Read article
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Recent Update on Advanced Drug Delivery System
Abstract: Over the past decade, there has been a growing interest in the use of artificial intelligence (AI) technology for analysing and interpreting biological or genetic data, accelerating drug discovery, and identifying selective small-molecule modulators or rare molecules in addition to predicting their behaviour. The use of artificial neural networks (ANNs) for the rapid analysis of massive amounts of data, the development of novel hypotheses and treatment plans, the prediction of …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 1, 2023 · pp. 22–30 Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
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Multifactorial Diseases Becoming the Epigenetic Factor for the Genz
Abstract: This comprehensive paper investigates the complex interplay between multifactorial diseases, particularly obesity and cardiovascular disease (CVD), and their relationship with epigenetic mechanisms, highlighting the transgenerational implications of these interactions. The multifaceted nature of obesity and CVD, involving genetic predisposition, environmental influences, and epigenetic modifications, underscores the intricate pathways contributing to disease susceptibility and progression. Drawing upon a synthesis of diverse research findings, the paper elucidates the critical role of genetic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 16–22 Read article
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Deciphering Th-Related Gene Interactions in Chronic Spontaneous Urticaria: Bioinformatics Insights and Drug Affinity Exploration
Abstract: Objective: There has been a great deal of interest in how inflammatory dermatosis and The cell interact, but the etiopathogenesis of chronic spontaneous urticaria (CSU) is still inadequately comprehended. Through bioinformatics techniques, the purpose of this work is to elucdate the molecular mechanism underlying Th-related genes in CSU and seeks to find the highest affinity drug. Methods: The CSU RNA expression profiling dataset provided the basis for the investigation. The …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 1–15 Read article
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Millet Bran: Unveiling Its Potential Health Benefits
Abstract: Millet bran, derived from various millet grains, has emerged as a potent nutritional source, rich in fiber, vitamins, minerals, antioxidants, and omega-3 and omega-6 fatty acids. Its rising popularity is driven by its gluten-free nature, nutrient density, and sustainability. This review aims to explore the potential health benefits of millet bran, focusing on its digestive health, blood sugar control, heart health, antioxidant properties, and fatty acid composition. The Millet brand …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 11–19 Read article
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Advances in Solubility Enhancement Strategies for Poorly Water-soluble Drugs: A Comprehensive Review
Abstract: Solubility enhancement holds significant importance in the field of pharmaceutical research as it aims to augment the solubility and bioavailability of drugs that possess low solubility. Poorly soluble drugs pose a considerable challenge in drug development due to their tendency to display inadequate absorption, bioavailability, and therapeutic efficacy. The advancement of solubility enhancement techniques encompasses a wide range of approaches, including physical and chemical methods, as well as innovative technologies …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 01–09 Read article
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Geological and Geophysical Studies of the Ninety East Ridge: A Brief Review
Abstract: The Indian Ocean serves as a unique laboratory for studying the impact of both global and regional stressors on environmental changes over various geological epochs. Its distinct hydrological conditions and geographical location make it an ideal focal point for research into these phenomena. Of particular interest within the Indian Ocean is the Ninety East Ridge (NER), which holds significance as the world's longest linear rise. Researchers have long hypothesized that …
Published in International Journal of Marine Life · Vol. 1, Issue 1, 2024 · pp. 8–19 Read article