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217 articles for “pathogenic infection”
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Pathogenesis, Immune Response and Vaccine Development in Amoebiasis
Abstract: Worldwide, approximately fifty million cases of invasive E histolytica disease occur each year and resulting in more than 100,000 deaths. It is the second leading cause of mortality due to a protozoan parasitic infection after malaria. Entamoeba histolytica infection is associated with considerable morbidity and mortality in the form of intestinal and extra-intestinal amoebiasis especially in developing countries. Recent molecular studies have conclusively proved that there are morphologically similar species …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 3, 2015 · pp. 30–35 Read article
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Prolonged Antibiotic Use and Reproductive Challenges in Dairy Cows: Implications for Ovarian, Uterine, and Overall Reproductive Health
Abstract: The widespread use of antibiotics in dairy farming has raised concerns regarding its potential impact on reproductive performance. Prolonged antibiotic administration can disrupt endocrine regulation, alter ovarian function, impair uterine health, and compromise overall fertility in dairy cows. This review explores the multifaceted consequences of antibiotic exposure on reproductive physiology, highlighting its effects on hormonal balance, follicular dynamics, uterine microbiota, and embryo viability. Antibiotics may induce hormonal imbalances that interfere …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 22–40 Read article
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Biological Membranes: Structure, Function, and Their Roles in Disease Pathophysiology
Abstract: Biological membranes are important structures that control cellular work, signal transmission, transport, and communication. Dysfunction of membranes has been considered in the development of many diseases, such as cancer, neurodegenerative diseases, and infections, with the distortion of lipid composition, protein activity, and cellular connections involved in the pathogenesis of the disease. The damage on membrane can be caused by oxidative stress, genetic mutation, and environmental influence to disrupt cellular homeostasis. …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 38–46 Read article
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Lysogenic Phage Cocktails with Embedded Fluorophores for Field Wound Diagnostics.
Abstract: Rapid and accurate detection of wound infections in field settings remains a critical challenge in emergency and military medicine. Conventional microbiological diagnostics are time- consuming and laboratory-dependent. Bacteriophages, particularly lysogenic phages, offer high specificity toward bacterial hosts and can be engineered as diagnostic tools. A translational framework was developed for lysogenic bacteriophage cocktails embedded with fluorophore reporters for rapid, point-of-care wound diagnostics. Mechanisms of phage infection, lysogenic integration, and fluorophore …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 Read article
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Candida auris—Behaviour and Prognosis
Abstract: The genus Candida contains around two hundred different species. For over a decade, health authorities and institutions around the world have been on edge due to the unprecedented rise of Candida auris as a multidrug-resistant fungal pathogen, which poses a serious global threat due to its potential to cause nosocomial outbreaks and deep-seated infections with staggering transmissibility and mortality. The Centers for Disease Control and Prevention and other international organisations …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 1, 2023 · pp. 1–6 Read article
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Chicken Feather Degradation Using Thermus aquaticus YT-1 and Application of Keratinolytic Protease Produced
Abstract: ABSTRACTAim of the study undertaken was to develop a process to manage chicken feather waste, without use of potential infectious microorganism. Biodegradation of chicken feather mediated by production of keratinolytic protease involving use of non- pathogenic thermophile Thermus aquaticus was investigated. The structural complexity of native chicken feather acts as inducer to increase protease production as compared to feather meal. The keratinolytic protease produced demonstrated more than 50 % stability …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 1, Issue 1, 2012 · pp. 1–11 Read article
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In vitro Combination Studies of Antibiotics against Bacterial Pathogens
Abstract: Antibiotic-resistant microorganisms are emerging worldwide and causing serious complications. As these microorganisms are resistant to most of the contemporary antibiotics, their control is becoming as a global health concern. Therefore, there is a need for new alternative compounds or strategies that are effective against these microbial infections and in preventing or delaying their resistance. This study was carried out to test Rifampicin as an adjuvant therapeutic agent in the treatment …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 2, Issue 1, 2012 · pp. 27–38 Read article
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Infective Endocarditis, Result of Chronic Periodontal Disease: A Real and Present Danger
Abstract: Introduction: Endocarditis is an inflammation of the endocardium, the inner lining of the heart and heart valves. It is usually caused by bacteria and is associated with high mortality and morbidity. It can result from transient bacteremia from the oral cavity. Streptococci are the primary colonizers of tooth surface and are instrumental in development of the complex oral biofilm, dental plaque. Streptococcus sanguinis is one of the abundant oral commensals …
Published in Research and Reviews: A Journal of Dentistry · Vol. 14, Issue 4, 2023 · pp. 6–10 Read article
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Infective Endocarditis, Result of Chronic Periodontal Disease: A Real And Present Danger
Abstract: Introduction: Endocarditis is an inflammation of the endocardium, the inner lining of the heart and heart valves. It is usually caused by bacteria and is associated with high mortality and morbidity. It can result from transient bacteremia from the oral cavity. Streptococci are the primary colonizers of tooth surface and are instrumental in development of the complex oral biofilm, dental plaque. Streptococcus sanguinis is one of the abundant oral commensals …
Published in Research and Reviews: A Journal of Dentistry · Vol. 13, Issue 1, 2022 · pp. 6–10 Read article
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Safe Practices: Sterilization and Disinfection in Orthodontics– A Review
Abstract: Sterilization is a process by which an article, surface or medium is freed of all microorganisms either in vegetative or spore state. Disinfection is the process of destroying or inhibiting most pathogenic microorganisms and inactivating some viruses, hence reducing microbial contamination to safety levels. To prevent the cross infection which spreads through the different types of instruments used during orthodontic management is of outmost importance as a preventive measure. The …
Published in Research and Reviews: A Journal of Dentistry · Vol. 6, Issue 2, 2015 · pp. 32–38 Read article
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In silico Bioprospection and Identification of Propitious Herbal Mitigators Against Highly Virulent Pathogenic Strains of Bacteria Like Vancomycin Resistant Enterococci
Abstract: Vancomycin resistance genes have been isolated from various strains of Enterococci, owing to the high rate of recombination and vast potential of disseminating resistant genes between Enterococcal strains. Various virulent factors contribute towards the dissemination of infections caused by such Multi-Drug Resistant (MDR) strains, ultimately leading to a devastating state of environmental contamination and cross infection. Minimizing the prevalence of these strains by multiple control efforts therefore is of paramount …
Published in Research & Reviews : Journal of Herbal Science · Vol. 4, Issue 1, 2015 · pp. 1–14 Read article
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Vaccines Through Time: Conventional Foundations and Next-Gen Innovations–Part 1
Abstract: Vaccination serves as a critical pillar of global public health, markedly decreasing infection rates and associated mortality. Traditional vaccine platforms such as live attenuated, inactivated, toxoid, and subunit vaccines have demonstrated effectiveness against pathogens like Mycobacterium tuberculosis and Plasmodium spp., yet they are constrained by antigenic variability, limited immune persistence, and complex production processes. Breakthroughs in synthetic biology, structural antigen design, and computational vaccinology have driven the development of advanced …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 · pp. 53–70 Read article
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The Parasitic Fingerprint: Tracing Infection to Host Illness
Abstract: Parasitic infections remain a major global health burden, causing significant morbidity and mortality, particularly in tropical and subtropical regions. A critical aspect of disease pathogenesis is the unique molecular and cellular imprint left by parasites in their hosts, termed the “parasitic fingerprint.” These fingerprints encompass parasite-derived proteins, nucleic acids, metabolites, extracellular vesicles, and host responses, including gene expression changes, cytokine profiles, and metabolic adaptations. Advances in multi-omics technologies, which integrate …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 29–50 Read article
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Cronobacter sakazakii and Its Significance in Dairy Industry
Abstract: Cronobacter sakazakii is an emerging opportunistic human pathogen of immense importance to food industry. The organism is found to be responsible for life-threatening bacterial infections such as necrotizing enterocolitis, bacteremia, and meningitis in neonates and infants with a high mortality rate. It has the ability to form biofilms and can survive in desiccated environments such as milk powder, powdered infant formulae for long period of time. It possesses antibiotic resistance …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 6, Issue 3, 2017 · pp. 1–7 Read article
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Antimicrobial Resistance in Veterinary Medicine
Abstract: Antimicrobial resistance is a worldwide public health issue that impacts both human and animal populations. The use of antibiotics in veterinary medicine plays a significant role in the development and spread of antimicrobial resistance, contributing to resistant pathogens that impact both animals and humans. Antibiotics are widely utilized in animal husbandry, not only for treating diseases but also for preventing illness and enhancing growth in livestock. While this practice supports …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 11–15 Read article
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Identification of Diabetic Foot Ulcer by Using Filter and Pixel Classification Methods
Abstract: Ulceration of the foot in diabetes is common and disabling and frequently leads to amputation of the leg. Mortality is high and healed ulcers often recur. The pathogenesis of foot ulceration is complex, clinical presentation variable, and management requires early expert assessment. Interventions should be directed at infection, peripheral ischaemia, and abnormal pressure-loading caused by peripheral neuropathy and limited joint mobility. Despite treatment, ulcers readily become chronic wounds. Diabetic foot …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 2, Issue 1, 2015 · pp. 22–31 Read article
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Respiratory Tract Infection: A Focus on Upper Respiratory Tract Infection
Abstract: Respiratory tract infection (RTI) is considered as one of the most important public health problems in developing countries. Respiratory infections that occur in upper respiratory tract are seen with great frequency in both children and adults. RTIs are common cold, sore throat, sinusitis, laryngitis, pharyngitis, earache, and otitis media. Upper respiratory tract infections (URTIs) are general illnesses that are often treated with antibiotics even though bacteria cause only 25% of …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 1, 2014 · pp. 30–35 Read article
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Incidence of Community acquired MRSA in the nasal swabs of general population of Gulbarga region
Abstract: Background: Methicillin resistant S. aureus (MRSA) has emerged as a major pathogen in both community and hospital settings. Nasal carriage of S. aureus represents a major risk factor for the development of infection with this bacterium. Objective: The aim was to study community acquired MRSA incidence among nasal swabs of general population of Gulbarga. Methods: Nasal swabs from anterior nares were collected for the isolation of S. aureus from 224 …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 3, 2017 · pp. 8–13 Read article
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Necrotizing Enterocolitis (NEC): A Devastating Neonatal Gastrointestinal Disorder
Abstract: Necrotizing enterocolitis (NEC) represents a formidable challenge in neonatal medicine, particularly afflicting premature infants with its characteristic features of severe intestinal inflammation and necrosis. Despite advancements in neonatal care, NEC continues to exact a heavy toll, standing as a prominent cause of morbidity and mortality in this vulnerable population. Its multifaceted etiology, encompassing prematurity, enteral feeding practices, alterations in microbial colonization, and episodes of intestinal ischemia, underscores the complexity of …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 78–83 Read article
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Development of vaccine against Helicobacter pylori using Bioinformatics approaches
Abstract: Helicobacter pylori (H. pylori) are a widespread kind of bacteria which flourish in the digestive tract and have a propensity to damage the stomach lining. The microbe infects around 60% of the adults globally. H. pylori infections are responsible for most of stomach and small intestine ulcers. Using Bioinformatics approaches, we have identified certain proteins that possess the resistance, essentiality and virulence factors for this pathogen. Computational tools and servers …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 3, 2019 · pp. 34–68 Read article