Candida auris—Behaviour and Prognosis

Abhijeet Sande; Vinit Patil; Prasad Karande; Ashwinirani S.R

Abstract

The genus Candida contains around two hundred different species. For over a decade, health authorities and institutions around the world have been on edge due to the unprecedented rise of Candida auris as a multidrug-resistant fungal pathogen, which poses a serious global threat due to its potential to cause nosocomial outbreaks and deep-seated infections with staggering transmissibility and mortality. The Centers for Disease Control and Prevention and other international organisations have classed it as an urgent concern due to its unique traits not discovered in other yeasts. Epidemiological warnings have also been issued because of the C. healthcare-associated A. auris epidemics in the context of the current COVID-19 pandemic. In this overview of the relevant literature, we compile the most recent findings about C. auris, from virulence to treatment and outbreak control, with a focus on identifying knowledge gaps and potential research areas since its initial description. Candida auris, virulence, pathogenesis, epidemiology, candidaemia, antifungal drugs, outbreak, and diagnosis are the focus of the present study.

Abstract

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