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686 articles for “Validation”
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Molecular Docking Analysis of Phytocompounds from Ficus hispida Aagainst Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 Read article
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Molecular Docking Analysis of Phytocompounds from Ficus hispida Against Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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Predicting Dielectric Constants of Polymers Using Molecular Structural Descriptors and Explainable Machine Learning: A Data-Driven Approach
Abstract: Accurate prediction of dielectric constants in polymeric materials is fundamental to the rational design of advanced electronic components, energy storage capacitors, flexible substrates, and high-frequency communication circuits. Conventional approaches to identifying suitable polymer dielectrics rely on extensive experimental synthesis and characterisation, which are both time-consuming and resource-intensive. In this work, an explainable machine learning framework is developed to predict the dielectric constant of polymers directly from molecular structural descriptors derived …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 297–304 Read article
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Artificial Intelligence-Assisted Multi-Objective Optimization of Agricultural Biomass-Reinforced Polymer Composites
Abstract: Agricultural biomass can reduce the environmental burden of polymer composites, yet its heterogeneous structure creates competing effects on strength, moisture resistance, density, and process ability. This study developed an artificial intelligence-assisted framework for balanced composite formulation. Experimental data of agricultural biomass reinforced polymer composites were gathered, harmonized and validated using leakage controlled validation. The mechanical and physical properties were predicted by artificial neural networks and conventional regression models. Explainable analysis …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Neuro-Symbolic Agentic AI for Autonomous Scientific Discovery: Integrating Deep Reinforcement Learning, Quantum Simulation, and XAI-Audited LLM Hypothesis Generation in Drug Target Identification
Abstract: The exponential growth of multi-omics data and the increasing complexity of disease-associated protein interactomes have rendered conventional drug target identification pipelines computationally and epistemologically inadequate. This paper presents the Neuro-Symbolic Agentic AI for Scientific Discovery (NS-AASD) framework, a unified architecture that cohesively integrates deep reinforcement learning (DRL) exploration strategies, variational quantum simulation (VQS) of protein conformational dynamics, and XAI-audited large language model (LLM) hypothesis generation within an autonomous scientific discovery …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 2, 2026 Read article
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Orthostride: An Internet of Medical Things-Enabled Smart Rehabilitation Footwear System for Real-Time Monitor
Abstract: The orthopedic rehabilitation goal of controlled weight bearing, a stable gait progression, and early recognition of hazardous situations for safe mobility is traditionally met through time, scheduled in-clinic observation and clinician induction, and patient report. In this work, Orthostride, a smart rehabilitation footwear prototype intended to augment postoperative and injury-related lower extremity restoration through continuous sensing, embedded decision logic, local feedback, and remote telemetry, is proposed. This system incorporates force …
Published in International Journal of Electronics Automation · Vol. 4, Issue 2, 2026 Read article
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Advanced Quantitative Analysis of Dynamic Recovery during Warm Working of FCC Alloys
Abstract: Metal working processes of warm working require an advanced quantitative analysis of dynamic and static recovery of dislocations to control microstructures and crucial shape forming properties. Feasibility of dynamic recovery by thermal glide and static recovery by climb of constricted jogs, applicable to ausforming, nano bulk forming by SPD and normalizing has been addressed to design new steels, used for hulls, and tribologically superior bearings. Predictive dislocation recovery analysis shows …
Published in Journal of Materials & Metallurgical Engineering Read article
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An Efficient Method of Fault Analysis using Artificial Neural Network
Abstract: In the power system, there are many techniques to identify and classify the faults. So, it is utmost important to choose the suitable technique. In this paper, a novel technique based on ANN have been proposed. When abnormal conditions occur in the system, the purposed method identifies and classify the fault to protect the system from the faults and stop from the big hazards. Simulation of purposed Simulink model have …
Published in Current Trends in Signal Processing Read article
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Power Estimation Approach for Artix 7 FPGA using Machine Learning Technique
Abstract: This paper presents the power estimation approach using a suitable machine learning technique. Artix7 FPGA has been chosen as the target FPGA (Field Programmable Gate Arrays) platform for understanding the methodology of power estimation. There are various approaches of power estimation for FPGAs that have been given in the literature viz. probabilistic, statistical, and LUT- based, etc. In the past few years, the demand for hand-handled devices like smartphones, tabs, …
Published in Research & Reviews: A Journal of Embedded System & Applications Read article
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Design and Simulation of Forging Die Towards Improving Life of Closed Die
Abstract: Forging is the metal forming process which is used for forming complex shaped component with geometrical accuracy. More than fifty percent of the forgings are processed through this way. Forged components required in many engineering sectors, most of them in the automotive sector. The majority of the safety critical component and load bearing structural components are process through it. By using forging process production of complex component is faster with …
Published in Journal of VLSI Design Tools and Technology Read article
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Detection of Stator and Rotor Winding Faults in Induction Motor using Park’s Vector Approach
Abstract: The Induction Motors in every rotating machine’s heart and it’s a very important component in a much. Almost 90 percent of the Induction Motor use in industry as a prime mover. So Induction Motor is necessary to Condition Monitoring for Economic Running Cost. Condition Based Monitoring of Induction Motor has become an important and difficult task for Engineers and Researchers mainly in Industrial applications. Several Condition Monitoring Methods (Technique) including …
Published in Journal of Control & Instrumentation Read article
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Design of Secure Biometric-based Access Mechanism for Cloud Services
Abstract: In our data-driven society, the demand for remote information storage and computation services is increasing exponentially, as is the need for secure access to such information and services. during this project, we have a tendency to style a replacement biometric-based authentication protocol to produce secure access to an overseas (cloud) server. Within the planned approach, we have a tendency to think about biometric information of a user as a secret …
Published in Journal of Experimental & Applied Mechanics Read article
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Mapping of Dangerous Glacial Lakes by Using Systematic Extraction Approach in Different Catchments of Upper Indus Basin (UIB) Pakistan
Abstract: The glaciers are nature's most valuable fresh water resource for irrigation, industry, and hydroelectric growth, as well as for the present and future needs of millions of people who live downstream. Numerous of the waterways in the HKH region receive a significant percentage of ice melt water from this solid reservoir. Many of the glaciers which consist of massive amount of permanent snow and ice are found to generate several …
Published in Research & Reviews : Journal of Space Science & Technology Read article
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Failure Analyses of 16 mm Thick SA 516 GR 70 Auto Clave
Abstract: With the acceleration of global industrialization, there is a demand for high-or low-pressure storage of liquids or gases. Because of the complicated operating conditions that will inevitably encounter a possible hazard, pressure vessel design is a critical responsibility. Previous failure studies have revealed that the presence of local loads and discontinuities increases pressure vessel fracture. As a result, a detailed examination of pressure vessel steel from the standpoint of fracture …
Published in Trends in Mechanical Engineering & Technology Read article
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Thermo-mechanical Analysis of Orthotropic plate under Sinusoidally Distributed Thermal load by using Trigonometric shear Deformation Theory (TSDT)
Abstract: For the thermal analysis of simply supported square and rectangular plates applied to sinusoidal distributed linear thermal load throughout the plate thickness and in combination with sinusoidal distributed transverse mechanical loading, a trigonometric shear deformation theory is proposed. In this work, a sinusoidal function in terms of thickness coordinates is being used in the displacement field in conjunction with the transverse shear deformation effect. The normal and shear stress can …
Published in Journal of Experimental & Applied Mechanics Read article
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Research Paper on Thermal Comfort Analysis of Tractor Considering Multi-Parameters
Abstract: The main functions of a vehicle cabin are to provide a comfortable and relaxing environment for its operator and to protect them from vibrations, noise, and other adverse influences. Modern agricultural tractor cabins are complicated, high-efficiency systems, and the goal of their development is to reduce their negative influence on the environment. Main factors for thermal comfort are the dry-bulb temperature, relative humidity, surrounding surface temperature, and air motion. A …
Published in Journal of Mechatronics and Automation Read article
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FEA Simulation for Optimization of Laminated Composite Plate with Cutout in Free Vibrations
Abstract: Laminated composites have a large application in engineering. The work done in this study is to see the free vibration response of graphite epoxy composite square plate subjected to different boundary conditions. Finite element analysis has been done on the software ANSYS. The results obtained by the simulation have been compared with those obtained from a published data obtained by semianalytical solution. It is observed that the solutions through ANSYS …
Published in Journal of Experimental & Applied Mechanics Read article
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Effect of Initial Temperature and Diameter of Ethanol Droplet on Evaporation Dynamics in Convective Air Medium
Abstract: Ethanol is a suitable biofuel as it has fewer toxic emissions and higher-octane numbers. For spray combustion applications, the gas phase motion must be considered while numerically investigating the fundamental aspects of droplet evaporation and combustion processes. Hence, we have numerically simulated the evaporation dynamics of an isolated spherically shaped ethanol droplet under a forced convective air environment in the absence of gravity. The momentum transfer between two phases is …
Published in Journal of Polymer & Composites Read article
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Fingerprint Liveliness Detection in Biometric Authentication: A Survey
Abstract: In the world of cyberspace, presentation attacks (PA) on biometric systems have grown to be a major worry. The review of the literature suggests that these systems are more susceptible to spoofing or presentation attacks (PAs), which frequently cause the authentication or identification system to completely fail. To combat against presentation attacks (PAs), the presentation attack detection (PAD) or anti spoofing methods have been developed to validate the liveness of …
Published in Journal Of Network security Read article
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Determination of fire Resistivity of Door and Window Materials at Portharcourt Markets in Nigeria
Abstract: The persistence of fire outbreaks in markets is a problem in Nigeria and the repetition of this problem is very frequent at Port Harcourt in Rivers State. To curtail this problem, research was made on the three major markets in Port Harcourt with the aim of determining the fire resistivity of their door and window materials, in order to generate guidelines for designing doors and windows of market buildings in …
Published in International Journal of Architectural Design and Planning · Vol. 1, Issue 1, 2023 Read article