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142 articles for “Inhibitory”
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Antibacterial Activity of Seed Extracts of Okra (Abelmoschus esculentus) against Selected Pathogens
Abstract: The aim of the study was to determine the antibacterial potency of aqueous and ethanoic extracts of Abelmoschus esculentus seeds. Antibacterial activity of aqueous and ethanoic extracts of A. esculentus seeds were evaluated against selected foodborne pathogens; Listeria monocytogenes, Bacillus cereus, Salmonella enterica, Staphylococcus aureus and Escherichia coli) using agar well diffusion method by measuring the clear zone of inhibition diameter in (mm). It was observed that the aqueous and …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 6, Issue 1, 2017 · pp. 1–5 Read article
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Antibacterial Property of Crocus Sativus L.
Abstract: ABSTRACTCrocus sativus commonly called saffron has been used widely in Middle East and South East Asia as a drug to promote health and to fight diseases. Saffron though cultivated in different parts of the world, is mainly cultivated in Iran. It has wide range of medical uses such as antitumor, antifungal and antiinflammatory activities. Characteristic components of saffron are crocetin, picrocrocin and safranal that are responsible for color, bitter taste, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 1, Issue 1, 2012 · pp. 17–23 Read article
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Allelopathy Effect of Phytochemicals in Laticiferous Species Sarcostemma brunonianum Wight & Arn and Ficus tsjakela Burm. f on Vegetative Growth of Sorghum bicolor (L.) Moench
Abstract: The present experimental work was focused out to determine phytochemicals of two medicinal laticifers Sarcostemma brunonianum and Ficus tsjakela and to check the allelopathy potential on Sorghum bicolor under in vitro conditions. Allelochemicals are phytocompounds excreted during the process of secondary metabolism. Chemical components may occur in leaves, stem, root, latex, rhizomes, flowers, fruits, seeds and even in pollen grains. Plant latex supports defense in milk yielding plant species. The …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 43–50 Read article
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Comparative Study on the Antibacterial Activity of Pomegranate Rind Extract
Abstract: AbstractPomegranate (Punica granatum), is a fruit-bearing deciduous shrub grown easily all over the world. In India, these fruits are used in the Ayurveda for treatment of many diseases. The present study emphasized on the antibacterial activity of the peel extract (rind) of two Punica granatum varieties (Kesar and Ganesh) on Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Bacillus sps. and Pseudomonas aeruginosa. Methanol extract was found to be effective in Kesar …
Published in Research & Reviews : Journal of Herbal Science · Vol. 2, Issue 1, 2013 · pp. 1–6 Read article
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Isolation, Characterization and Molecular Identification of Potential Probiotic Bacterium, Bacillus amyloliquefaciens CS4 from gut of Snakehead Fish, Channa striata (Bloch, 1793)
Abstract: The present study was to isolate and characterize the potential probiotic bacterium from the gutof healthy fish, Channa striata. Totally, 37 bacteria were isolated from the gut region, in whichonly 25 isolates that showed catalase negative were selected. Among the selected isolates, CS4exhibited maximum inhibitory activity against fish (Aeromonas hydrophila, Vibrio harveyi,Vibrio parahaemolyticus) and human (Serratia marcescens) pathogenic bacteria. Theisolate CS4 exhibited potential tolerance to 0.5% bile salts at 24 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 2, 2019 · pp. 1–10 Read article
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Antibacterial Activity of Plant Extracts and Its Phytochemical Analysis
Abstract: Emergence of multi-drug resistance in human and animal pathogenic bacteria as well as undesirable side effects of certain antibiotics has triggered immense interest in the search for antimicrobial drug of plant origin since there is no resistance developed to the drugs that are of plant origin. The antibiotic resistance was observed by testing with commonly used antibiotics against test microorganisms and then diameter of zone of inhibition was compared to …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 1–11 Read article
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Antibiotic Resistance Studies in Streptococcus mutans Isolated from Dental Plaque Samples
Abstract: Dental plaque is an archetypical biofilm composed of a complex microbial community. It is the etiological agent for major dental diseases such as dental caries and periodontal disease. Streptococcus mutans has been heavily implicated in dental plaque formation. The control of plaque can be achieved by mechanical oral hygiene procedures. However, in many cases, that is not enough to completely get rid of the biofilm. The addition of antiplaque or …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 64–72 Read article
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Antimicrobial Peptide (AMP): Effective Antiacne Agents with Broad Application in the Treatment of Acne
Abstract: Antimicrobial peptides are a group of peptides that can cause a tremendous effect on the treatment of various diseases caused by bacteria, fungi, viruses, and parasites. Antimicrobial peptides are biological molecules that show their presence in mammals, plants, and microbial species. Antimicrobial peptides contain a unique sequence of amino acids that forms structural motifs, making them unique. The presence of this unique structural molecule makes them able to cause a …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 13, Issue 1, 2023 · pp. 39–46 Read article
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Green synthesis of zinc oxide and copper oxide nanoparticles and their effect against wilt fungus, Fusarium udum.
Abstract: Nowadays nanoparticles (NPs) come out as powerful tools to enhance crop production and protection. Biosynthesis of NPs has a vital role and an alternate to chemical and physical methods because it is simple, easy, eco-friendly, and free from chemical hazards. Zinc oxide (ZnO) and copper oxide (CuO) NPs were synthesized from leaves extract of Lantana camara (L.) and Nerium oleander (L.) and characterized by using several techniques such as transmission …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 13, Issue 3, 2023 · pp. 1–5 Read article
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Comparative Study of Extraction and Characterization of Chitosan by Chemical and Biological Method from the Crab Shell Waste and Analyzing its Anticancer Activity
Abstract: Crab shell waste causes environmental pollution, So it is in need to process the waste into useful chitosan The crab shell waste act as an alternative for chitosan production The chitosan molecule appears to be a suitable polymeric complex for many biomedical applications. Chitosan is an amino polysaccharide and a versatile, natural polysaccharide. The specific objective of this study is to compare chitosan from the exoskeleton of freshwater crab obtained …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 8, Issue 1, 2019 · pp. 22–32 Read article
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In Silico Induced-Fit Molecular Docking and Pharmacokinetic Investigations of Pentacyclic Compounds as Promising Inhibitors of Cyclooxygenase-2 (COX-2) and Lipoxygenase (LOX)
Abstract: The current search involves the discovery of cyclooxygenase-2 (COX-2) (PDB ID: 3LN1) and lipoxygenase (LOX) (PDB ID: 1N8Q) inhibitory potentials of some pentacyclic macromolecules by employing the Maestro 9.1 software where Glide module was utilized for the induced-fit docking (IFD). In addition to it, the critical pharmacokinetic aspects such as QPPMDCK, QPlogPo/w, % human oral absorption, QPPCaco, and QPlogS were estimated. The study fruitfully opened the therapeutic pharmacodynamic perspectives and …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 2, 2018 · pp. 13–17 Read article
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Screening of Some Triterpenoids Isolated from Terminalia arjuna as Inhibitors of Angiotensin Converting Enzyme to Prevent Cardiovascular Diseases
Abstract: Natural products have been shown to present interesting biological and pharmacological activities and are used as chemotherapeutic agents. Plants have historically been used in treating cardiovascular diseases (CVD) and are recognized for their ability to produce secondary metabolites. Secondary metabolites obtained from different plants have been the starting material for designing different drugs. Many useful phytoconstituents have been isolated from Terminalia arjuna. Tannins and flavonoids are responsible for its anticancer …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 3, 2014 · pp. 12–19 Read article
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Killer of the Killer—Myeloperoxidase Inhibitor from Siddha System of Medicine
Abstract: Two proprietary siddha medicines such as NiKu plus and S.I.V.A. herbal drops were evaluated for myeloperoxidase (MPO) inhibition by in vitro enzyme assay. The MPO plays an important role in the predisposition of various complications both in diabetes mellitus (DM) and in psoriasis. Both NiKu plus and S.I.V.A. herbal drops showed high inhibitory activity of MPO. The findings suggest that regular use of NiKu and S.I.V.A. is must for patients …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 3, 2018 · pp. 31–34 Read article
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Herbal Medication for Diabetes Mellitus
Abstract: Diabetes is a metabolic disorder in which blood sugar is high. Symptoms linked with high blood sugar include frequent urination, increased thirst and hunger. Complication in diabetes can be acute or severe. Acute complications include diabetic ketoacidosis, hyperosmolar, hyperglycemic or death; while serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, and damage to the eyes. Medications used to treat diabetes do so by lowering blood sugar …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 5, Issue 3, 2018 · pp. 8–10 Read article
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Antimicrobial Potential of Methanolic Extract of Barringtonia acutangula (L.) Gaertn Fruits
Abstract: Barringtonia acutangula is a middle-sized plant which is distributed in Meghalaya, Assam, West Bengal, Madhya Pradesh, Bihar and Odisha, used in treatment of various ailments. The present work has investigated the antimicrobial activity of methanol extract of Barringtonia acutangula fruit against six resistance bacterial strains such as Enterococcus faecalis, Staphylococcus aureus, Acinetobacter bumannii (Gram positive) and Citrobacter freundii, Enterobacter aerogenes, Escherichia coli (Gram negative). The antibacterial activity was evaluated by …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 3, Issue 3, 2016 · pp. 13–18 Read article
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Antifungal, Antioxidant Activity and Phytochemical Analysis of Extracts from Vitex rivularis (Lamiaceae)
Abstract: The present study was designed to investigate the biological properties of methanolic extracts of leaves and seeds from Vitexrivularis. Leaves and seeds extracts were prepared by maceration in methanol. Phytochemicals analysis was performed by colorimetric method, chemical reaction method and high-performance liquid chromatography (HPLC). The broth microdilution method was used to evaluate the in vitro activity against three strains of Candida albicans and 17 isolates of two yeast species (Candida …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 1, 2020 · pp. 23–48 Read article
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Advanced Local Drug Delivery Approaches for Periodontitis: A Strategic Intervention
Abstract: Periodontal disease, one of the most prevalent oral diseases is caused by the gram negative bacterial infection of periodontal pocket identified by inflammation of subgingival plaque and degeneration of alveolar bones, teeth, dental cementum and periodontal ligaments. 80% of American adult and more than 50% of Indian community suffers from this chronic inflammatory disease depicting the severity of the disease. The objectives of the available therapies are to minimize the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 9, Issue 1, 2018 · pp. 4–11 Read article
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Studies on Extraction and Purification of Total Phenolic Content from Methanolic Extract of Syzygium Cumini Seeds
Abstract: Syzygium cumini is commonly known as Jamun fruit and belongs to Myrtaceae family. It contains various nutritional values like sugars, vitamins, lipids, carbohydrate content, organic acids, minerals. Mainly this seed contains various phytochemicals like phenolic compounds (gallic, ferulic, caffeic), flavonoids (quercetin, rutin, kaempferol), carotenoids (β-carotene, γ-carotene, lycopene) and other compounds are present. This seed also shows pharmacological properties like antioxidant, antimicrobial, anti-inflammatory, antimutagenic, enzyme inhibitory and tonic effects etc. In …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 12, Issue 2, 2022 · pp. 8–12 Read article
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Design Approach based Formulation of Deformable Liposomes and their In vitro Skin Permeation
Abstract: Leukemia is the common cause of disease and its worldwide incidence is increasing. Cytarabine pyrimidine nucleoside analogs most widely used for the treatment of leukemia, but the major obstacles to existing treatments are adverse effect and poor patient’s compliances. To provide sustained drug release with minimum side effects and to develop more patients affable formulation, the authors investigated the transdermal delivery of cytarabine through deformable liposomes. The present work demonstrated …
Published in Trends in Drug Delivery · Vol. 4, Issue 3, 2017 · pp. 14–25 Read article
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Onepot Multi-component Synthesis, Characterization and Biological Applications of Dicationic Ionic Liquids
Abstract: A series of dicationic ionic liquids have been prepared and confirmed with FT-IR, 1H NMR,13C NMR,31P NMR as well as High resolution mass spectroscopy impact technique. The present methodology possesses more advantages such as high yields, simple procedure, short reaction times and mild conditions. All the synthesized compounds were evaluated for their antimicrobial activity based on zone of inhibition. The ionic liquid, 4-butane diaminium NI,NI,NI,N4,N4,N4 hexapropyl dibromide was exhibited remarkable …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 2, 2020 · pp. 16–39 Read article