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1368 articles for “Calculations”
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Theoretical Study of UV Surface Waves in AlAs and AlN
Abstract: Surface waves excited at the interface between polar semiconductor surface and a dielectric when electromagnetic waves of appropriate frequency are incident on it. When the incident electromagnetic energy in the form of photons is absorbed, these surface excitations generate. They are of different kinds such as plasmon, phonon, exciton etc. Plasmon is the quanta of valence electron oscillation; phonon is the quanta of lattice vibration and exciton is the quanta …
Published in Research & Reviews : Journal of Physics · Vol. 12, Issue 1, 2023 · pp. 7–13 Read article
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2D-QSAR (Quantitative Structure Activity Relationship) Study of Probable Inhibitors for Oral and Cervical Cancers, Generation of Model for Pharmacophore Prediction
Abstract: Twenty-four analogs, conjugates and congeners of curcumin reported as inhibitors against HPV 16 E6 and E7 protein targets have been selected for generating QSAR model. The 46 descriptors were calculated using Schrodinger program version quikprop 9.2. Two alternative methods have been used to generate QSAR models. The first model generation was built on 5 descriptors namely glob, QPlogS, CIQPlogS, IP (eV), human oral absorption which were subjected to multiple linear …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 1–13 Read article
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Study of Price Variation of Anti-infective Eye Preparations
Abstract: To analyze the percentage cost variations among different brands of commonly prescribed ophthalmic drugs. The cost of different brands of commonly used ophthalmic drugs was sorted out by referring the latest Current Index of Medical Specialities, Indian Drug Review and Retail drug store. The cost of five dosage forms in INR of each brand, cost ratio and percentage cost variation ware calculated. Our study findings showed a very high fluctuation …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 2, 2018 · pp. 10–12 Read article
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The study of Density Functional Theory for dispersion relation in Carbon nanotube with dielectric medium in a coupling mode
Abstract: The author shall study the excitation of Surface Plasmon and Phonon on cylindrical polar semiconducting material. The possibility of their interaction has been discussed with the help of dispersion relation for the dual mode of CNT by using inherent properties of the dielectric interface in dual mode. The phonon dispersion relation of the CNT is calculated by large supercells containing an isolated nanotube, Density functional Theory, and plane wave basis …
Published in Research & Reviews : Journal of Physics · Vol. 12, Issue 3, 2023 Read article
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Exploring Molecular Structural Requirement of Acetylcholinesterase Inhibitors Using Molecular Docking Study
Abstract: To explore the molecular structure requirement of acetyl-cholinesterase inhibitors, we used some flavonoid derivatives and calculated its binding interaction with acetylcholinesterase enzyme using 1EVE PDB. Flavonoids are one of the largest class and plant secondary metabolites known to have variety of biological activity for human wellbeing. Also reported its acetylcholinesterase inhibitory potency by various researchers. To know the properties and selection of flavonoids, we were used databases through Google Scholar, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 3, 2018 · pp. 20–34 Read article
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Formulation Evaluation and Optimization of Orodispersible Tablets of Pantoprazole Sodium by the using of Different Superdisintigrants
Abstract: The objective of this study was to formulate and optimize an orodispersible formulation of pantoprazole sodium using a 32 factorial design for optimized the superdisintigrant concentration. Various concentration (2%,4%,6%) of superdisintegrants (SSG, CP) were added in formulation, all processing steps are carried out at temperature below 250C and relative humidity less than 35%. Procedure to manufacture orodispersible tablets by direct compression was established. The results show that the presence of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 3, 2017 · pp. 11–20 Read article
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Aloe vera (Aloe barbadensis): A Scientometrics Perspective (1989-2018)
Abstract: The study is primarily concerned to analyse the publication trend of literature pertinent to Aloe vera/Aloe barbadensis. To evaluate the research trends of Aloe vera Web of Science database is used to extract the data. It is evident that among the most prolific nations, India (594; 20.42%) leads the other nations in the publication count, followed by USA (446; 15.33%) and then by Iran (214; 7.36%). The literature available by …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 1, 2020 · pp. 18–23 Read article
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Wound Healing Effect of Methanolic Extract of Barringtonia acutangula Fruits in Streptozotocin Induced Diabetic Rats
Abstract: The present study is undertaken to evaluate wound healing effect of methanolic extract of Barringtonia acutangula fruits (MEBA) in streptozotocin induced diabetic rats. Diabetes is induced by administration of streptozotocin 45 mg/kg i.p. Both excision and incision models were used in rats. In the excision wound model, the wound area of each animal was measured on days 0, 2, 4, 6, 8, 10, 12 and 14 after inflicting the wound. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 3, Issue 1, 2016 · pp. 24–29 Read article
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In Silico Assessment of Drug like Properties of Some Thiadiazole and Oxadiazole Derivatives as HDAC Inhibitors
Abstract: Purpose: To investigate in silico the drug-like properties of some thiadiazole and oxadiazole derivatives as HDAC inhibitors. Methods: We used Chemdraw Ultra 11.0 to redraw all chemical structures. Furthermore, some applications, such as Bio-Loom for Windows - version 1.5, Molinspiration Property Calculator, and ACD/I-LAB, were used to forecast the drug-like properties of thiadiazole and oxadiazole derivatives, including relative molecular mass (MW), partition coefficient log P (cLog P), number of hydrogen …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 2, 2022 · pp. 1–13 Read article
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Drug-likeness and 3D-QSAR Analysis of 1,2,3-triazoles as Novel Potent HIV-1 Vif Inhibitors: An approach in the development of Leads in the Treatment of HIV Infection
Abstract: AbstractThe human immunodeficiency virus type 1 (HIV-1) Vif protein is one of various primate lentiviral accessory proteins that act as a virulence factor to advance viral duplication and persistence. 3D quantitative structure-activity relationship (QSAR) modeling of thirty-six (36) newly discovered 1,2,3-triazole analogs as potent novel inhibitors of HIV-1 Vif to predict their biological activity (pIC50), to try to improve/optimize it using some numerical data of HIV-1 Vif inhibitors based on …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 3, 2022 · pp. 23–37 Read article
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Simple, Direct and Stability-Indicating UV Spectrophotometric Assay of Pioglitazone Hydrochloride in Pharmaceuticals
Abstract: Pioglitazone hydrochloride (PGH) is an antihyperglycemic agent used in the treatment of type-2 diabetes mellitus. A simple and straight forward UV-spectrophotometric method is presented for the determination of PGH in bulk drug and tablets by measuring the absorbance of drug solution in 0.1M H2SO4 at 269 nm. A plot of absorbance versus concentration obeyed Beer’s law over 2–36 µg ml-1 concentration range (r = 0.9981) with a molar absorptivity of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 3, 2017 · pp. 7–16 Read article
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Ligand Efficiency in Relation to 3D Physicochemical Characters of Novel HIV-1 Vif Antagonist: An Approach in The Optimization of HIV Drugs
Abstract: AbstractLigand efficiency is a design framework commonly used in drug discovery. Thirty-six (36) newly discovered 1,2,3-triazole analogues as potent new inhibitors of HIV-1 Vif were subjected to quantitative structure-property relationship (QSPR) modeling to predict their ligand efficiencies (LE) in an attempt to improve/optimize it by using some numerical data of HIV-1 Vif inhibitors based on their physical and chemical properties (descriptors). Various 3D physicochemical properties or descriptors were calculated from …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 50–59 Read article
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Trikadu for De-worming, Associated Health Problems and use of Efficacy Screening for Quality Control
Abstract: Trikadu choornam/tablet is a Sastric Siddha Medicine with three herbs black pepper (kali mirch), ginger (adhrakh) and long pepper (pippali). It is known to have multiple therapeutic benefits. But trikadu also contain anti-helminthic activity. In the current article, the deworming ability of Trikadu was evaluated. The evaluation was done on two different worms i.e., Pheretima posthuma (PP) and Tubifex tubifex (TT). The time and concentration required for the paralysis of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 12, Issue 1, 2022 · pp. 1–4 Read article
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Determination of Gastric Irritation Inducing Effect of Iron-Containing Unani Compound Formulations In Animals
Abstract: AbstractBackground: Iron is the most commonly used metal for human welfare on earth and also a vital element for sustenance of life.Iron deficiency is a common affliction of human beings all over the globe and presents as iron deficiency anaemia. Most effective and preferred treatment of iron deficiency is replenishment of iron by oral administration. Successful completion of treatment depends on tolerance of the prescribed drug by a patient. Oral …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 9, Issue 3, 2022 · pp. 27–30 Read article
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Assessment of Self-Medication Practice and Drug Storage on Private Pharmacy Clients in Jimma Town, Oromia, South West Ethiopia
Abstract: A number of individuals in developing countries do not attend physicians for their illnesses, instead they commonly use self-medication. Self-medication could be using drugs existing in home like over the counter (OCT) drugs, traditional medicine, prescription only drug. Self-medication is not always bad; hence for the over the counter drugs, it is beneficial. Most of the time drugs stored on unsafe place may result in decrease in drug's efficacy. The …
Published in Trends in Drug Delivery · Vol. 1, Issue 3, 2014 · pp. 17–29 Read article
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Prescriber’s Adherence to the Basic Principles of Standard Prescription Order Writing in Dessie Referal Hospital, South Wolli Zone, Northern Ethiopia
Abstract: Objective of the paper is to assess prescriber’s adherence to the basic principles of prescription order writing in Dessie Referal Hospital, for which a retrospective study was conducted using a sample of 384 prescriptions. A prescription was selected using simple random sampling technique. Data was collected using check list and analyzed using hand tallying and scientific calculator. Study shows good adherence for some variables and poor adherence for other variables. …
Published in Trends in Drug Delivery · Vol. 1, Issue 3, 2014 · pp. 37–46 Read article
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A Research Study on Impact of Pharmacovigilance Implications over OTC Drug Safety Surveilliance in Optimization of Rational Drug Usage
Abstract: The Presentresearch study involves in application of Pharmacovigilance implications over OTC drug safety surveillance in optimization of rational drug usageand was conducted in bhuvaneswari medicals and tripuraswari medicals, R.T. Nagar, Bangalore, Karnataka, India over a minimum period 4 months from 16th April 2020 to 16th august 2021with an estimated sample size was 250–300 for the present study.The data was collected by using different scales and methods were implemented to monitor …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 1–12 Read article
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Analytical Techniques Used In Metabolomic Analysis
Abstract: Comprehensive studies regarding metabolomics provides us ample of information about the structural properties and various other parameters pertaining to the molecule under study. Metabolomics is employed for managing long-term illness such as cancer, diabetes. It’s applications also stretch to treating diseases such as tachycardia along with various cardiovascular diseases. It is used to treat inborn errors of metabolism which are found out in infants. These molecules along with processes of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 14, Issue 3, 2023 · pp. 52–68 Read article
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Use of Machine Learning Algorithms in Power System Load Forecasting: A review
Abstract: The electrical load forecasting has become one of the most important fields of research for secured, efficient, accurate, reliable power dispatch and management. The main aim of load demand forecasting is to predict the load demand for accurate generation scheduling, system security and economic dispatch of load at any time. Many Authors have done research on the evaluation of load forecasting methods, to improve the accuracy of prediction. In load …
Published in International Journal of Microwave Engineering and Technology Read article
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Characterization of CeO2-NiO Thin Film Produced by Jet Nebuliser Technique
Abstract: CeO2 –NiO composite solution was sprayed as thin films by using JET nebulizer technique at the substrate temperature of 250°C. The film was characterized by X-ray diffractometer and crystallite size, lattice constant, crystallinities, phase transformations were measured. The UV-Vis spectrometer analysis was used to calculate the band gap, absorbance and percentage of transmission of the thin films was reported. The emission and excitation spectra of the sample were reported. The …
Published in International Journal of Nanobiotechnology Read article