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1846 articles for “experience”
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Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
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Neurodegeneration and Cognitive Decline: Causes, Consequences, and Treatment Approaches
Abstract: Neurodegenerative diseases gradually destroy nerve cells, often leading to fatal outcomes. The phrase includes a wide range of clinical problems, such as a variety of Neurological conditions include movement disorders, like Parkinson’s disease (PD) and progressive cognitive impairments, with Alzheimer’s disease (AD) being the most common among them. A loss of neurones and synaptic connections, typically in later life, is a prevalent feature of Usually, the onset and development of …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 47–59 Read article
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Comparative Investigation of Solar Still by Varying Basin Water Depth and Integrating Energy Storage Material and Steel Wool Fibre
Abstract: The main obstacle to human life in the modern age was the unequal distribution of drinking water on Earth. The demand for drinking water is increasing due to population growth and industrial exploitation, while supply levels are essentially unchanged. Because of its simplicity in construction, techno-economic advantages, and environmental friendliness, solar energy is still regarded as one of the best methods for turning saline into potable water. The main disadvantage …
Published in Trends in Machine design · Vol. 12, Issue 1, 2025 · pp. 1–11 Read article
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Optimizing Data Processing Efficiency in Big Data: Advanced MapReduce Algorithm Innovations
Abstract: The exponential growth of big data in recent years has created an urgent need for innovative and efficient processing frameworks capable of managing and analyzing massive and complex datasets. Among these, MapReduce has gained prominence as a powerful tool for distributed data processing due to its simplicity and scalability. However, traditional MapReduce frameworks often encounter significant limitations in terms of efficiency, scalability, and resource optimization, particularly when handling large-scale and …
Published in International Journal of Data Structure Studies · Vol. 3, Issue 1, 2025 · pp. 1–7 Read article
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Care Sched: Doctor and Patient Appointment Management
Abstract: The medical appointment system is a web application that uses PHP, JavaScript, and CSS to improve the efficiency of booking medical appointments. It features two interfaces: an admin side where patients and doctors manage their appointments and a user side where they may handle an appointment and to view records, and manage their medicines. The web platform that the system makes available provides a convenient online experience from any internet-enabled …
Published in International Journal of Computer Science Languages · Vol. 3, Issue 1, 2025 · pp. 1–12 Read article
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Multi-Screen Interface Applications in Graphical User Interface for Ornamental Efficiency in Computer Programming
Abstract: Use of multi-screen interfaces for graphical user interfaces (GUIs) has transformed the way we do computer programming by improving the speed, efficiency and usability. Also, these interfaces help programmers multitask easily by decoupling the different functionalities, code debugging, and data visualization in real-time through multiple terminals which cuts down context switching, thus maintaining workflow organization. Multi-screen GUI applications enable developers to organize their workspace and work efficiently, with customized or …
Published in International Journal of Computer Science Languages · Vol. 3, Issue 1, 2025 · pp. 27–31 Read article
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Zika Virus: Long-term Effects and Vaccine Development Efforts
Abstract: Zika virus (ZIKV) is a mosquito-borne flavivirus that gained international concern following the 2015-2016 outbreak in the Americas. Although most ZIKV infections are asymptomatic or mild, the virus presents significant public health risks due to its ability to cause severe neurological complications, especially in pregnant women and their offspring.Congenital Zika Syndrome (CZS) encompasses a range of fetal abnormalities, including microcephaly, vision impairment, hearing loss, and developmental delays. Infants exposed to …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 25–28 Read article
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Au@Sio2@PVP-DCMD Membranes: A Breakthrough in Heavy Metal Removal and Antibacterial Defense
Abstract: This study investigates the development and characterization of multifunctional gold-doped silica (Au@SiO₂) membranes for water distillation and antibacterial applications. The manufacturing process integrated gold nanoparticles into silica matrices using sol-gel techniques. Structural analysis was conducted using SEM (showing uniform pore distribution with an average pore size of 40-50 nm), FTIR (confirming Si-O-Si and Si-Au-Si bonding peaks at 525 cm⁻¹ and 1310 cm⁻¹ respectively), EDX (revealing gold nanoparticle content of 1.5 …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 13–27 Read article
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Material Characterization Analysis of Fiber Reinforced Composites
Abstract: The study investigates the physical characteristics of PAN carbon fabric/epoxy composite which is a material commonly utilized in aerospace, defense, and automotive sectors. The material has exceptional mechanical properties like high specific strength and hardness. The materials utilized in this experiment are T-300 PAN carbon fabric, LY556 Epoxy resin, and HY5200 hardener to create pre-preg materials. Then the laminate was pre- pregged in a die mold of identical shape matched, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 230–243 Read article
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IoT Grass Cutting Robot
Abstract: The demand for efficient and sustainable lawn care solutions has escalated with the increasing urbanization and the need for environmentally friendly practices. In response to this, our group embarked on the development of an innovative IoT-enabled grass cutting robot. This project aims to address the limitations of traditional lawn mowing methods by integrating modern technology to automate and optimize the maintenance process. The proposed grass cutting robot leverages Internet of …
Published in Journal of Mechatronics and Automation · Vol. 12, Issue 1, 2025 · pp. 41–52 Read article
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Literature Review On Nanotechnology In Dentistry
Abstract: Nanotechnology is a relatively new field in dentistry that utilizes nanomaterials, nanorobots, and nanotechnology for diagnosing, treating, and preventing dental diseases. Nanotechnology has revolutionized various fields of dentistry, offering innovative solutions that enhance patient care, improve treatment outcomes, and contribute to the overall advancement of dental science. This cutting-edge technology has found applications in several areas, including restorative dentistry, dental implants, early cancer diagnosis, dental hypersensitivity, and pain management, among …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 2, 2025 · pp. 19–23 Read article
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Next-generation Operating Systems: AI-driven Autonomy, Quantum Integration, and Edge Computing
Abstract: The rapid evolution of computing paradigms is driving the need for next-generation operating systems that seamlessly integrate artificial intelligence, quantum computing, and edge processing. Traditional operating systems, while efficient for classical computation, lack the necessary capabilities to handle real-time AI-driven decision-making, quantum processing, and decentralized edge networks. This study explores how future operating systems will incorporate AI-driven autonomy to enhance resource management, quantum integration to leverage superior computational power, and …
Published in Journal of Operating Systems Development & Trends · Vol. 12, Issue 1, 2025 · pp. 25–36 Read article
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Introducing New Operating Systems for Computer
Abstract: This study introduces new operating systems (OS) designed to meet the evolving demands of modern computing environments. As technology progresses, the limitations of traditional operating systems in terms of efficiency, security, and scalability have become evident. The proposed new OS models aim to address these challenges by incorporating advanced features such as optimized resource management, enhanced security protocols, and improved user interfaces. Additionally, these systems leverage emerging technologies like artificial …
Published in Journal of Operating Systems Development & Trends · Vol. 12, Issue 1, 2025 · pp. 37–47 Read article
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Impact of Adaptive Learning, LMS, and Personalized Skill Development on Industry Recruitment Alignment
Abstract: This paper discusses the impact of adaptive learning on the development of skill and self-learning, and it portrays a methodology framework to design an adaptive learning system that works with industry recruitment objectives. The paper distinguishes different approaches to learning, namely teacher-centric and student-centric, rigid and adaptive, competitive and collaborative, and explains that each learner has their own learning style, preference, and level of knowledge and skill acquisition. The paper …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 12, Issue 1, 2025 Read article
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Exploring Phytomedicine: Innovations, Efficacy and Future Directions
Abstract: The use of plant-derived substances for therapeutic purposes has long been a cornerstone of traditional medicine systems worldwide. With increasing interest in natural remedies, the field of phytomedicine is experiencing a revival, marked by innovations in research, formulation, and application. This review article explores recent advancements in phytomedicine, highlighting novel extraction technologies, and the efficacy of plant-based treatments in clinical settings. The review also addresses the challenges faced in phytomedicine …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 2, 2025 · pp. 32–50 Read article
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An Evaluation of the Effectiveness of a Self-Instructional Module on First Aid and Safety Measures for School Children (Aged 11–14 years) at PDR VVP Vidyalaya, Loni
Abstract: Background: School children are active youngsters. India is home to nearly 500 million young individuals, with approximately 370 million being children under 15 years old, highlighting their crucial role as the future of the country. Young children often exhibit naughty, defiant, and impulsive behavior. According to the World Health Organization’s Global report, in the South-East Asia Region, road traffic accidents, drowning, burns, and other injuries are leading causes of child …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 1, 2025 · pp. 17–22 Read article
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Hormonal Shifts and Vision Changes: Addressing the Needs of Women During and After Pregnancy
Abstract: Pregnancy and the postpartum period are marked by significant hormonal fluctuations that can profoundly affect a woman’s vision health. This review explores the relationship between hormonal shifts during pregnancy and the onset of common vision changes, including but not limited to dry eyes, blurred vision, and retinal changes. These changes are often temporary but can indicate underlying complications such as gestational diabetes, preeclampsia, and other pregnancy-related conditions that may threaten …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 19–24 Read article
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A Comprehensive Review of Literature on Endometriosis: Pathophysiology, Diagnosis, and Management
Abstract: The endometrium, a tissue that resembles the lining of the uterus, develops outside the uterus in endometriosis, a chronic and frequently painful illness. Other parts of the body may also be affected, however the ovaries, fallopian tubes, and the tissue lining the pelvis are the most frequently affected. Infertility, heavy menstrual flow, and pelvic pain are the main signs of endometriosis, though each person may experience these symptoms to varying …
Published in International Journal of Midwifery Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 1–5 Read article
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A Review of Drug Design Techniques Assisted by Computers to Combat Diabetes
Abstract: Diabetes mellitus is a global health concern characterized by chronic hyperglycemia and associated complications. The creation of innovative medicines with enhanced efficacy and safety profiles continues to be a top focus, notwithstanding improvements in treatment. A useful method in drug development, computer-aided drug design (CADD) makes it easier to identify possible therapeutic candidates and optimise lead molecules. An extensive synopsis of CADD tactics used in the fight against diabetes is …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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Numerical Simulation of Crack Growth in Dynamic Loading Conditions
Abstract: Because it is crucial for forecasting structural failures in engineering applications, crack formation in materials under dynamic loading circumstances has become a crucial study topic. In this work, finite element methods (FEM) are used to numerically simulate fracture propagation in dynamic stress situations. The impact of loading rates, material characteristics, and crack geometries on crack growth patterns are assessed in a thorough parametric research. The work uses sophisticated computational methods …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 2, Issue 2, 2024 · pp. 30–34 Read article