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354 articles for “therapeutics methods”
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Phyto-Entrapped Carbon Dots as Emerging Nanomaterials for Anti-Cancer Activity
Abstract: Phytoconstituent-loaded carbon dots (C-dots) represent an innovative approach in targeted cancer therapy, combining the therapeutic power of plant-derived compounds with the advanced capabilities of nanotechnology. These ultra-small, biocompatible nanostructures offer excellent fluorescence, tunable surface chemistry, and low toxicity, making them ideal for drug delivery, bioimaging, and theranostic applications. Traditional phytochemicals often face challenges like poor solubility, low bioavailability, and high first-pass metabolism barriers that C-dots help overcome. C-dots synthesized through …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 51–63 Read article
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Next-Generation mRNA Therapeutics: Self-Amplifying, Thermostable and Personalized mRNA Vaccines in the Era of Precision Medicine
Abstract: Messenger RNA (mRNA) technology has brought a major change in modern medicine, especially after its successful use in COVID-19 vaccines. However, early mRNA vaccines faced several problems such as low stability, strict cold storage requirements, and lack of personalized treatment. To overcome these challenges, next-generation mRNA technologies have been developed, including self-amplifying mRNA (saRNA), thermostable mRNA vaccines, and personalized mRNA vaccines. This article discusses the development of mRNA therapeutics, the …
Published in International Journal of Vaccines · Vol. 3, Issue 1, 2026 · pp. 38–54 Read article
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Application of Nanotechnology in Rasaushadhi Preparations for Nanoparticle Synthesis—A Comparative Review
Abstract: Nanotechnology—a constantly evolving branch of science and technology—reveals great potential for the early diagnosis, care and mitigation of numerous illnesses. In the field of Ayurvedic medicine, a variety of herbal, herbo-mineral and herbo-metallic compositions are used in formulations namely Bhasma, Kupipakwa Rasayana, Kharaliya Rasayana since a long era. To minimize the particle size of the substance (nanoparticles), procedures such as Shodhana, Nirvapa, Mardana, Bhavana, Marana, and others are carried out. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2024 · pp. 1–8 Read article
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Exploring The Therapeutical Potential Of Pongamia Pinnata For Herpes Simplex Virus Type 1 (HSV-1)
Abstract: Objective: Pongamia pinnata (L.), commonly known as Indian beech or pongam tree, is a tropical plant renowned for its medicinal properties in traditional medicine systems. Extracts derived from various parts of Pongamia pinnata have demonstrated antimicrobial, anti-inflammatory, and immunomodulatory activities. Such attributes make it a compelling candidate for exploring its therapeutic potential against HSV infections. Thymidine kinase is the target protein mostly used in the treatment of HSV1 infections. In …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 1–9 Read article
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A Review about Scope of Traditional Medicinal Plants in a New Drug Discovery
Abstract: ‘AYUSH’ is the most important traditional system of medicine, which has been practised since thousands of long years by our ancestors. AYUSH has a very good healing power for so many problems by using both traditional and natural medicine. The new drug discovery is taking long time to produce its products and thus there is a reduction in number of new drug approvals due to different issues like legal problems …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 7, Issue 2, 2017 · pp. 1–3 Read article
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Formulation and Development of Ibuprofen Floating Tablet
Abstract: The investigation focused on optimizing a gastric floating drug delivery system (GFDDS) for Ibuprofen tablets. It employed polymers like HPMC K4M and Carbopol 940 to improve Ibuprofen's bioavailability and therapeutic effectiveness. GFDDS, with lower bulk density than gastric fluids, remains buoyant in the stomach, extending gastric residence time. Compatibility assessments, via DSC analysis, indicated harmony between the polymers used, with no observed interaction between the polymer and the drug. The …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 24–29 Read article
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Immunoassay and its Biotechnological Relevance
Abstract: Immunoassays are bioanalytical methods to quantify of the analyte (antigen) depending on its reaction with an antibody. These methods are based on a competitive binding reaction between a fixed amount of labeled analyte and a variable amount of unlabelled sample analyte for a limited amount of binding sites on a highly specific anti-analyte antibody. Applications of immunoassays are diagnosis of diseases, therapeutic drug monitoring, clinical pharmacokinetic and bioequivalence studies in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 7, Issue 1, 2017 · pp. 17–28 Read article
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Psoriasis: Causes, Symptoms, Treatment, Effect on Quality of Life and Future Therapeutic Prospects: A Detailed Review
Abstract: Objective: This review’s objective is to provide an outline of how psoriasis is caused, what are its symptoms, what are the conventional methods being employed for treatment, and how future prospects can take over the conventional methods. We also aim to put light on how psoriasis is having a huge impact on people’s life quality in various fields of life and how this effect can be measured using instruments or …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 31–49 Read article
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Brief Review on Novel Technology in Breast Cancer Chemotherapy
Abstract: Breast cancer is cancer that develops from breast tissue. Breast cells contain receptors for the two types of hormones estrogen and progesterone. They also contain receptors for a protein called HER2, which induce normal cell growth. Around two out of three women with breast cancer have cells that bear receptors for estrogen and progesterone, and just about 20–30% of breast cancers have too many HER2 receptors. Exploitation chemotherapy to treat …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 2, 2018 · pp. 22–26 Read article
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Therapeutic Potential of Terminalia arjuna Bark in the Management of Hemorrhoids: A Comprehensive Review
Abstract: Background: Hemorrhoids appear frequently among anorectal disorders since they create vascular swelling together with pain symptoms, while leading to bleeding and mucosal tissue tending to slide out. Though effective therapy exists, traditional treatments produce various adverse effects and lead to recurrence and inconsistent patient following of medical recommendations over the long term. Plantbased therapeutic medicines have gained rising demand, which leads experts to investigate medicinal plants with established pharmacological effects. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 22–32 Read article
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Progression in multi-omics and immunological research on host-parasite interactions: Transcriptomics, proteomics, genomics, metabolomics, and immune responses
Abstract: The interaction occuring between hosts and parasites is a quick and multi step-complex biological process that tries to influence disease outcomes. In recent years, multi-omics approaches, such as transcriptomics, proteomics, genomics, metabolomics, and immunological studies, have gathered substantial eye in dissecting these interactions at a microscopic level. These techniques enable a vast understanding of the molecular structures involved in parasitic infections and host defense mechanisms. This article reviews the advancements …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 1–6 Read article
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A Comprehensive Analysis of Aloe Vera Gel Processing and Its Antidiabetic Properties: A 3D Computational Biology Perspective"
Abstract: This expansive review paper delves into the intricate realm of Aloe vera gel processing and its potential antidiabetic properties, augmented through the lens of 3D computational biology. The review amalgamates insights from various references to elucidate the handling, harvesting, and juice extraction of Aloe vera gel. Additionally, it explores diverse products derived from Aloe vera, such as Aloe juice, Aloe health drink, and Aloe dessert, providing an extensive understanding of …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 10, Issue 2, 2023 · pp. 18–21 Read article
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In Situ Investigation of Hemidesmus indicus Phytocompound Extracts as a Therapeutic Target for Acute Myeloid Leukemia
Abstract: Objective: Acute myeloid leukemia (AML) is an apoptotic condition in the hematopoietic system induced by the differentiation and maturation of stem cells into erythrocytes, and leukemic cell proliferation is suppressed as the PI3K-Akt-mTOR pathway is pharmacologically targeted with certain inhibitors. As a result, in silico molecular docking of compounds against AML receptors, CTMP, was used in computational research on Hemidesmus indicus to uncover therapeutic phytochemicals for AML. Thus, this study …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 38–53 Read article
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A Review of Drug Design Techniques Assisted by Computers to Combat Diabetes
Abstract: Diabetes mellitus is a global health concern characterized by chronic hyperglycemia and associated complications. The creation of innovative medicines with enhanced efficacy and safety profiles continues to be a top focus, notwithstanding improvements in treatment. A useful method in drug development, computer-aided drug design (CADD) makes it easier to identify possible therapeutic candidates and optimise lead molecules. An extensive synopsis of CADD tactics used in the fight against diabetes is …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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Homeopathy: Beyond the Art of Micro-dosage
Abstract: Homeopathy has, ever since its inception, evolved as a refined method of remedy diagnosis and prescription, offering a wide variety of medicinal substances for use in therapeutic practice and preventative medicine in micro-dosages. It does not follow conformist medical thinking. Hence, it has been continually attacked by the orthodox, or conventional medical establishments for all the wrong reasons and also without taking into account its unique, individualised patient-centric nature of …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 7, Issue 1, 2018 · pp. 5–13 Read article
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Periodontal Regeneration: Histological Perspective
Abstract: Periodontitis involves an inflammatory process of bacterial origin, affecting the periodontal tissues and provoking the destruction of the supporting tissues to the teeth. The ultimate goal of periodontal treatment seeks to preserve the teeth in relatively functional and comfortable good health, and at the same time maintaining the aesthetic expectations of the patient. The rationale for most of the therapeutic procedures is “regeneration of periodontium”. Periodontal regeneration can be assessed …
Published in Research and Reviews: A Journal of Dentistry · Vol. 12, Issue 3, 2021 · pp. 26–45 Read article
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Scope of Single cell Genomics: Bioinformatics Review
Abstract: To study the Expression profile of genes and its regulations in single cell resolutions is one of the major factor to improvise the current therapeutic options. Bulk RNA sequencing has been discussed by many groups before, better understanding over analysis methods with standard best practice guidelines were demonstrated extensively in past 2 decades. The single cell resolution of RNA expression data analysis has many varieties of software in open source …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 9, Issue 1, 2022 · pp. 43–51 Read article
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Virtual Reality Graded Exposure Therapy For Phobia And Ptsd
Abstract: By combining virtual reality technology with graded exposure therapy, Virtual Reality Graded Exposure Therapy (VRGET) transforms the treatment of anxiety disorders. VRGET uses controlled exposure to anxiety-inducing stimuli using immersive virtual environments, addressing the global problem of anxiety disorders. By simulating real-world scenarios, VRGET provides a structured and immersive approach that allows individuals to gradually confront their fears in a controlled, supervised, and safe environment. Technology offers adaptable scenarios tailored …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 2, 2025 Read article
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A Review on Environmental Pollution Mitigation by Fungal Proteases
Abstract: Proteases comprise a vital group of proteolytic enzymes with variety of functions. These enzymes possess the enormous commercial potential and have been used in several industrial processes, including food industry, leather processing, detergent industry and therapeutic applications. As well as they are used as an environmental pollution cleaning agent. Proteases are the replacement of conventional method of silver recovery from the X-ray films. Among the microbial enzymes only proteases constitute …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 3, 2017 · pp. 32–37 Read article
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Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article