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294 articles for “phytochemical study”
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Evaluation of Anthelmintic, Analgesic and Neuropharmacological Activity of Merremia hederacea
Abstract: The aim of the present study was to evaluate the phytochemical screening, anthelmintic activity, analgesic properties and neuropharmacological activity of the leaf extract of Merremia hederacea (Family: Convovulaceae). After preliminary phytochemical screening, the leaf extract of Merremia hederacea contain flavonoids, tannins, alkaloids and reducing sugars. Anthelmintic activity test was done by comparing the time of paralysis and the time of death of earthworms Pheretima posthuma compared with the standard drug, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 1, 2020 · pp. 28–33 Read article
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In Situ Investigation of Hemidesmus indicus Phytocompound Extracts as a Therapeutic Target for Acute Myeloid Leukemia
Abstract: Objective: Acute myeloid leukemia (AML) is an apoptotic condition in the hematopoietic system induced by the differentiation and maturation of stem cells into erythrocytes, and leukemic cell proliferation is suppressed as the PI3K-Akt-mTOR pathway is pharmacologically targeted with certain inhibitors. As a result, in silico molecular docking of compounds against AML receptors, CTMP, was used in computational research on Hemidesmus indicus to uncover therapeutic phytochemicals for AML. Thus, this study …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 38–53 Read article
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In vitro Evaluation of Kigelia pinnata Leaves for Its Antioxidative and Anticancer Activity
Abstract: Previous studies suggest that the Kigelia pinnata leaves have useful effects against diseases mediated through oxidative stress and cancers. In this study, leaves of Kigelia pinnata were studied for presence of different phytochemical constituents, anti-oxidant and anti-cancer activities.Crude methane extracts of Kigelia pinnata leaves showed cytotoxic activity in vitro against non-small cell lung cancinoma (A-549) cells using the MTT assay. Phytochemical evaluation showed the existence of alkaloids, terpenoids, flavonoids, tannins …
Published in Research and Reviews: A Journal of Health Professions · Vol. 9, Issue 1, 2019 · pp. 26–30 Read article
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Zingiber officinale Rosc.: A Monographic Review
Abstract: ABSTRACTZingiber officinale Rosc. is native to Asia and is widely used as a culinary spice. It is well known in herbal medicine for stomachache, diarrhoea, nausea, etc. Modern interest in ginger is focused on its use in the prevention of nausea and vomiting, particularly motion sickness, as a digestive aid, and as an adjunctive treatment for inflammatory conditions, such as osteoarthritis and rheumatoid arthritis. So, the present paper is a …
Published in Research & Reviews : Journal of Botany · Vol. 1, Issue 3, 2012 · pp. 21–26 Read article
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Potential Application of Retama sphaerocarpa Plant in Pharmaceuticals
Abstract: The aim of this study was to evaluate the phytochemical and biological activity (antibacterial and antifungal) of Retama sphaerocarpa plant and the possibility to use it in pharmaceutical formulations. This plant is traditionally used only as healing remedies because of their antiseptic, antipyretic and antidiarrheal properties. Phytochemical screening of leaves and stems revealed the presence of flavonoids, alkaloids, tannins and steroids. The antimicrobial activity was determined on bacterial strains such …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 3, 2019 · pp. 22–28 Read article
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Targeting Homogentisate Dioxygenase Dysfunction in Alkaptonuria: Investigating Curcuma longa’s Therapeutic Potential
Abstract: Objectives: Alkaptonuria is known to have a faulty gene HGO in the metabolic process. In the present research work, the focus is towards investigating the therapeutic capabilities of the Curcuma longa upon the faulty Homogentisate dioxygenase gene using ligand-protein binding, which would assist in the corrective tyrosine metabolism. Methods: This study is based on the computational approach using different phytochemicals for evaluation of the potency against the abnormal Homogentisate dioxygenase …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 1–11 Read article
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Pharmacognostic and Phytochemical Investigation of Pods of Albizia lebbeck (L.) Benth.
Abstract: Albizialebbeck (L.) Benth. is well known as the medicinal plant in the Ayuerveda, Siddha and Unani system of medicines. The drug isolated from different parts of this plant is used in different sciences of medicines like Unani, Ayuerveda, allopathic, Sidda, naturopathic and homeopathic. The present investigation deals with pharmacognostical and primary phytochemical screening of the pod of Albbizzialebbeck (L.) Benth. The pharmacognostical studies include fluorescence, organoleptic evaluation and physicochemical analysis. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 6, Issue 1, 2019 · pp. 10–15 Read article
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Conservation of Some Wild Edible Plants Used by the Tribes of Bhiwapur Tahsil of Nagpur District, Maharashtra, India
Abstract: Plants are the integral part of Indian custom and social life. The disappearance of several plant species is affecting the quality of the day-to-day life of man in different ways. Hence, conservation of biodiversity and its sustainable utilization is of global importance for the development of the nation. The present study aimed to investigate the wild edible plants used by the tribes of Bhiwapur tehsil, belonging to different families, from …
Published in Research & Reviews : Journal of Herbal Science · Vol. 5, Issue 2, 2016 · pp. 14–19 Read article
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Antibacterial, Cytotoxicity Studies of Azukia mungo (L.) Masam and Correlation with in silico Docking Studies
Abstract: Introduction and Background: Azukia genus plants rich in proteinaceous anti-nutrients like tannins (especially condensed tannins) has been shown to have anti-bacterial activity against Staphylococcus aureus and antineoplastic activity against lung and liver cancer cells. Five types of procyanidins (condensed tannins) have already been isolated from Azukia mungo and structurally elucidated. But its activity against the Methicillin resistant Staphylococcus aureus (MRSA) has not yet been shown. Hence we focus our work …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 2, 2017 · pp. 21–31 Read article
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Phytochemical Evaluation of Vitex agnus-castus L Seeds Collected from Different Geographical Regions of the World
Abstract: AbstractVitex agnus-castus L (VAC) is an important medicinal plant. Seeds are used as a popular treatment for the management of female reproductive system disorders. Other uses include the treatment of hangovers, flatulence, fevers, benign prostatic hyperplasia, nervousness, dementia, rheumatic conditions, cold, dyspepsia, spleen disorders, constipation and promoting urination. VAC today is an important herb of commerce cultivated around the world. VAC seeds were collected from different geographical location—USA, EU and …
Published in Research & Reviews : Journal of Botany · Vol. 5, Issue 3, 2016 · pp. 21–28 Read article
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“Progen†Herbo-Mineral Formulation Modulates Spermatogenesis in Experimentally Induced Infertile Rats
Abstract: The present study was designed to evaluate the fertility potential of Ayurvedic proprietary medicine ‘progen’—a herbo-mineral formulation—in experimental rats. A total of 24 male wistar rats were rendered infertile by administration of tetracycline (22.5 mg/kg p.o) and restraining stress (2 h a day) for 7 weeks. At the end of 7th week, six animals were sacrificed. Blood serum was analysed for triglyceride (TG), total cholesterol (T-CHO), follicle stimulating hormone (FSH), …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 3, 2016 · pp. 11–23 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Medicinal Properties of Oxytenanthera abyssinica: A Narrative Review
Abstract: Oxytenanthera abyssinica, a plant local to the African landmass, has gotten a parcel of intrigued in later a long time for its conceivable restorative benefits; it has been utilized in conventional medication for decades since of its assumed mending capabilities. In spite of its long history, careful logical examination into its restorative potential is being attempted. This review paper explore into the multidimensional part of O. Abyssinica is in progressed …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 2, 2026 · pp. 21–42 Read article
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Ethnobotanical Study of Wild Edible Plants used by Tribes of Sawali Khurd
Abstract: The present study was designed to evaluate the phytochemical composition of the endangered medicinal plant of Moringa oleifera ‘Mungna’ belonging to family Moringaceace collected from Sawali Khurd of Wardha district, India. Moringa oleifera commonly called the horseradish tree, drumstick tree, ben oil tree, miracle tree, and Mother’s Best Friend, known for its multipurpose attributes, wide adaptability, and ease of establishment. Its leaves, pods and flowers packed with nutrients important to …
Published in Research & Reviews : Journal of Ecology · Vol. 7, Issue 2, 2018 · pp. 7–11 Read article
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Exploring Potential Phytochemicals for Myasthenia Gravis Treatment: A Molecular Docking and ADME Analysis Approach
Abstract: Objective: Muscle feebleness and exhaustion derived from a disruption in neuromuscular transference are hallmarks of the crippling autoimmune disease myasthenia gravis (MG). The drawbacks of the current MG therapy options are frequently partial efficacy and adverse effects. To investigate the potential of phytochemicals in MG control, in this work we integrated molecular docking with ADME (absorption, distribution, metabolism, and excretion) analysis using a computer method. We identified molecules exhibiting favorable …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 1–13 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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Phytochemical profiling and LC/MS analysis of Selaginella bryopteris (L.) Baker
Abstract: Selaginella bryopteris (L.) Baker, an endemic pteridophyte is found restricted to the Indian subcontinent mostly because of its environmental requirements of cool temperatures and optimum water availability. It is a drought-resistant species and shows curling in limited water supply reviving when water conditions are restored. This property makes this species a suitable plant for exploration of medicinal properties, although its restricted occurrence has limited this evaluation. The current study explores …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 1, 2025 · pp. 46–51 Read article
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In vitro Anthelmintic and Antibacterial Potentialities of Methanol Extract from the Leaf and Bark of Lawsonia inermis Linn. (Family: Lythraceae)
Abstract: Due to the availability of the genus Lawsonia in Bangladesh, the present study was aim to investigate the phytochemical screening, anthelmintic and antimicrobial potentialities of methanol extract from the leaf and bark of Lawsonia inermis L. The phytochemical screening was performed by chemical group tests for both the extract which indicate the presence of several chemical groups including steroids, alkaloids, flavanoids, tannins and saponins. The anthelmintic activity was performed by …
Published in Research & Reviews : Journal of Botany · Vol. 4, Issue 2, 2015 · pp. 1–5 Read article
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Phytochemical Evaluation in Various Leaf Extracts of Wild Bhendi
Abstract: The vast diversity of natural products have been used for combating human diseases for thousands of years, since they exhibit a wide range of biological properties that can be exploited for medical application. The present study was carried out to analyse the preliminary phytochemical constituents in various solvent extract of wild Bhendi. The results revealed the presence of medicinally active compounds such as alkaloids, tannin, phenol, saponin, flavonoids and glycosides …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 11, Issue 3, 2021 · pp. 23–28 Read article
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Pharmacological evaluation of Hepatoprotective activity of Indian medicinal plants Cordia Myxa and Canscora diffusa on wistar albino rats
Abstract: Two plants (Cordia myxa and Canscora diffusa), which were claimed to possess hepatoprotective activity, were selected. The Selected plants were authenticated by an expert botanist. In the current study, herbal extraction involving solvents of decreasing polarity (petroleum ether, ethyl acetate, and hydroalcoholic) was used to extract bioactive compounds from the plants of Cordia Myxa and Canscora diffusa in polyherbal preparations. A phytochemical evaluation was performed, including an acute toxicity study …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 31–44 Read article