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152 articles for “cancer”
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QSAR Modeling of a Novel Series of Methoxylated Chalcones as Antioxidant Agents Against Gram-Positive Bacteria Staphylococcus aureus
Abstract: Background: Chalcones are aromatic ketones belonging to the flavonoid family. They are plant-based compounds and are widely found in nature. For centuries, these bioactive molecules have been utilized in various traditional medicines for the treatment of several ailments. Chalcones have antibacterial, antiviral, antimalarial, antifungal, antioxidant, and antileishmanial properties. They are also used to treat inflammation and cancer. Chalcones act as angiogenesis inhibitors, an important factor in cancer progression and metastasis. …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 28–34 Read article
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Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
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Impact of Training Program on Recent Innovations in Oncology Among Nursing Professionals
Abstract: Introduction: In recent years, there have been significant advancements and trends in the field of oncology treatment in India. This study aimed to evaluate impact of training program on knowledge regarding recent innovations in oncology among nursing professionals. After ethical approval, a pre-experimental, one group pretest- post-test design was used to conduct this research at anursing college of Punjab. Methods: The sample was selected using the total enumerative sampling technique. …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 9–14 Read article
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Beyond Generalized Treatment: The Future is Personalized Medicine
Abstract: Personalized medicine, which is also called as precision medicine, is reestablishing the view of new healthcare by replacing the traditional "one-size-fits-all" approach with individual therapies made according to a patients unique genomic organization, environment, and lifestyle. This article talks about the scientific foundation, important applications, ethical challenges, and the significant potential of personalized medicine in enhancing the clinical outcomes. From oncogenic and genetic disorders to chronic diseases, the addition of …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 Read article
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CRISPR-Cas9: Revolutionizing the Genetic Frontier
Abstract: The rapid development of CRISPR/CRISPR-associated enzyme (Cas) technology has enabled truly customised treatment of human genetic disorders, paving the way for recent developments in the field of gene therapy. Because CRISPR/Cas can accurately target and edit individual genes within a genome, it has established itself as a formidable tool for genetic manipulation. CRISPR/Cas9 technology allows for precise editing of specific DNA sequences in an organism's genome. This method uses three …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Azepines, Chemistry, Synthesis and Reactions
Abstract: Azepines, which consist of a seven-membered cyclic compound featuring six carbon atoms, an additional nitrogen atom, and no double bonds between carbons, form a diverse group within organic chemistry. The fully hydrated form of this compound is called azepam (C6H13N). Compounds and their variants play crucial roles in pharmaceutical research due to their biologic attributes like cancer-fighting, bacteria-killing, fungus-busting, virus-suppressing, and inflammation-reducing capabilities. Various organic molecules found within nature draw …
Published in International Journal of Minerals · Vol. 2, Issue 2, 2025 · pp. 35–45 Read article
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Anticancer Potential and Other Therapeutic Activities of Curcumin & Its Derivatives
Abstract: Curcumin, a compound isolated from turmeric, is used in the management of various diseases due to its extensive medicinal properties. Curcumin, the principal polyphenol isolated from Curcuma longa (turmeric), has garnered immense scientific interest for its extensive medicinal properties, including potent anti-inflammatory, antioxidant, and anticancer activities demonstrated in preclinical models. An expanding body of research indicates broad therapeutic promise in managing diverse pathologies, from various cancers to chronic inflammatory, metabolic, …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 19–28 Read article
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Cell Membranes as Therapeutic Targets: Implications in Infectious and Metabolic Disorders
Abstract: This is a review of the crucial role played by cell membranes in health and disease with respect to their contribution to infectious and metabolic diseases. Dysfunction of membranes, such as membrane transporter changes and changes in lipid content, has been associated with a variety of diseases, including diabetes, cardiovascular disease, and cancer. The present therapeutic approaches are focused on attacking membrane constituents by disrupting the entry of pathogens or …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 47–53 Read article
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GenChrome-ML: A Machine Learning Framework for Early Detection of Chromosomal Disorders Using Genomic Data
Abstract: The increasing burden of chronic disease and cancer demands innovative, more rapid and effective diagnostic tools in the field of healthcare. The majority of current diagnostic tools are dependent upon clinical symptomology and manual evaluation, leading to delays in early detection and treatment. The development of artificial intelligence (AI) and machine learning (ML), in recent years, has offered opportunities for the enhancement of disease prediction, diagnosis and personalization of treatment …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 Read article
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In Silico Prediction of Multitarget Mechanism of Quinoline and Its Analogs on Phosphoinositide-3-Kinase Pathway Proteins
Abstract: Objective: Phosphoinositide 3-kinases (PI3Ks), the target of rapamycin (PI3K/Akt/mTOR, PAM), are a family of enzymes that play a role in the growth, proliferation, differentiation, motility, survival, and intracellular trafficking of cells, all of which are essential for healthy cellular function and are also connected to cancer. In this study, quinoline and its derivatives were employed to analyze its inhibition activity on the phosphoinositide-3-kinase pathway. Methods: In this work, eight phytocompounds …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 57–76 Read article
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Assessment of Knowledge and Estimated Burden of Life Style Diseases in a Rural Community
Abstract: Although rapid human evolution has brought about advancement, it has also caused several lifestyle ailments. People’s daily routines have drastically changed as a result of emerging technologies, and it paved the way for numerous life style disorders. According to reports, lifestyle diseases are a major cause of increased mortality globally. Our study highlights the prevalence of life style diseases in the rural community and the need for early identification and …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 33–38 Read article
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Implementation of Anticipating Rainfall Using Machine Learning
Abstract: Rainfall forecasting is crucial for many aspects of our national economy and should help prevent major seasonal droughts. Since agriculture is a beloved profession in many states, some Asian countries are economically hooked to decline. Previous precipitation info is beneficial. Farmers are cancerous in managing their crops, resulting in economic progress for the country. downfall prediction is hard for earth science scientists because of unordering time and unordered quantity of …
Published in International Journal of Satellite Remote Sensing · Vol. 1, Issue 1, 2023 · pp. 1–8 Read article
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To Assessment of the Effectiveness of a Structured Educational Program on Women's Knowledge of Sexually Transmitted Diseases in Rural Areas of Ludhiana, Punjab: A Quasi-experimental Study
Abstract: Background: Maintaining good health is of immeasurable value, as it empowers individuals to lead socially and economically fruitful lives. However, various disorders have the potential to disrupt one's health. Among these, sexually transmitted diseases (STDs) are the most prevalent disorders affecting the reproductive system and other bodily systems, resulting in significant consequences for both families and society. Sexually transmitted diseases (STDs) can be triggered by various microorganisms, including bacteria (like …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 19–26 Read article
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Evaluating Epidemiological and Physical Risk Factors in the Development of Chemotherapy-induced Peripheral Neuropathy (CIPN): An In-depth Systematic Review and Meta-analysis
Abstract: Background of study: Chemotherapy-induced peripheral neuropathy (CIPN) encompasses a range of adverse effects caused by various cytotoxic medications and stands as a primary source of pain among individuals who have survived cancer. In instances of pronounced and sudden CIPN, it might become necessary to diminish chemotherapy dosages or discontinue their application. Currently, no efficacious strategy exists for proactively preventing CIPN, managing established chronic CIPN is constrained, and the risk factors …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 10–21 Read article
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Nutraceuticals: Bridging Nutrition and Medicine for Future Wellness
Abstract: Nutraceuticals are items that can be classified as food or a component of food and provide medical or health benefits. This paper discusses the concept of nutraceuticals, their classification, and their role in promoting health and wellness. As of 2023, the worldwide nutraceuticals market is expected to be valued at approximately USD 317.22 billion, indicating a high rate of increase. Growth is projected to reach USD 626.02 billion by 2029 …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 26–36 Read article
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A Cross-sectional Study to Analyze the Knowledge, Attitude, and Practice of Nurses with Different Levels of Experience Towards End-of-Life Care in an Oncology Hospital
Abstract: Background: To render comprehensive nursing care for patients in end-of-life care, nurses’ knowledge, attitude, and practice are paramount. Aim: A cross-sectional study to analyze knowledge, attitude, and practice of nurses with different levels of experience towards end-of-life care in an oncology hospital. Design: Descriptive cross-sectional survey approach. Method: Nonprobability convenience sample of 147 nurses at oncology hospital in Apollo Hospitals (Apollo Proton Cancer Centre, Apollo Specialty Hospitals). Results: The main …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 1–11 Read article
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Comprehensive Overview of Carbohydrate Polymers
Abstract: Targeting drug delivery specifically to the colon has become increasingly crucial for treating various colonic diseases like colorectal cancer, amebiasis, ulcerative colitis, and Crohn’s disease. Numerous strategies have been developed for this purpose, including using enzymatically degradable polymers, employing prodrug-based approaches, coating drugs with polymers sensitive to time or pH changes, utilizing osmotically and pressure-controlled delivery systems. Polysaccharides activated by the colon's physiological environment show significant potential as they offer …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 8–21 Read article
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Effectiveness of Temporins for the Treatment of HPV Infections
Abstract: Objectives: Human papillomavirus (HPV), especially high-risk variants like type-16 have been linked to the formation of malignant tumors. HPV-16 has been implicated in most cases of cervical cancer in women. This study aims to assess the effectiveness of three types of temporin molecules, i.e., antiviral peptides secreted by certain frog species, for the inhibition of the viral L1 protein. Methods: In the present study, various computational tools were used to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 41–53 Read article
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Introduction to Biological Networks and their Contributions to Systems Biology
Abstract: Biological networks provide a conceptual framework to represent and analyze the intricate interconnections among the numerous components that make up living systems. This review paper elucidates the foundational principles of networks and their diverse applications in systems biology, highlighting their crucial role in understanding the inherent complexity of biological processes. Utilizing graph theory, these networks represent entities like genes, proteins, and metabolites as nodes, with their interactions depicted as edges. …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 53–70 Read article
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Physico-Chemical and Antioxidative Properties of Whey Protein Beverages
Abstract: Whey, the liquid left after milk casein precipitation, was utilized, and its physicochemical properties were assessed. The aim of the research was to analyze the availability of nutrients in whey by preparing a modified whey protein beverage. Natural and artificial whey protein beverages were prepared. We studied the shelf life of these beverages over a period of 0 to 11 days and compared them based on their acidity, viscosity, pH, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 1–6 Read article